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Efficacy of Ciprofloxacin for the Control of Streptococcal Infection in Cultured Fish, Flounder(Paralichthys olivaceus) and Eel(Anguilla japonica)
Park, S.C.(Seoul National University, Seoul, Republic of Korea) | Heo, G.J.(Chungbuk National University, Cheongju, Republic of Korea)E-mail:gjheo@cbu.ac.kr
Efficacy of ciprofloxacin was evaluated in laboratory and field studies for control of streptococcal infection in flounder and eel. In disc diffussion test, all streptococcal strains showed high sensitivity to the ciprofloxacin. Minimum inhibitory concentrations of ciprofloxacin against all streptococcal strains used in this study were less than 0.195 μg/ml. In laboratory studies where fishes were challanged with Streptococcus iniae, significant reductions in mortality were observed among fish receiving ciprofloxacin (in feed) at 100 mg/kg/body weight or more daily for 3 d when compared with mortality of non-medicated controls.
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