Data on studying of efficiency of application of immunobiological preparations on efficiency and other clinical and biochemical indicators for chickens-broilers are cited. It is established, that their application to chickens-broilers promotes increase of biological value of fowl as foodstuff and is economically expedient. Application of a preparation the Biococktail-NK in an optimum dose 0,1 - 0,2 ml/goal (10,0-20,0 million microbic bodies) has allowed to increase intensity of growth of chickens-broilers by 3,5%, to lower forage expenses for production of a gain of body weight of 1 kg on 4,95%, to raise safety of young growth of birds on 3,4 % and to lower a case of birds to 1,6% (technological norm of 5%). The carried out calculations have shown, that introduction of the Biococktail-NK in a ration of broilers is economically justified, as safety of young growth in 4th trial group has raised on 3,4%, in the third - on 2,5%, in the second - on 1,3%. On the basis of the spent research fowl of the delivered samples in which ration it was entered the probiotic Biococktail-NK from calculation 0,1 - 0,2 ml/goal (10,0-20,0 million microbic bodies) since daily age within the first 5 days into 4 cycles with an interval of 7 days till the end of the cultivation period is established, that on organoleptic, physical and chemical, bacteriological indicators, and also biological value and harmlessness does not concede to meat of control group and is good-quality. In the literature there are data about influence of biologically active substances on growth and development of bird. Despite it, about influence of probiotical and immunostimulatory preparations as separately, and in a complex with probiotics, on an organism of chickens-broilers it is not enough data that induces carrying out of scientific research in the given direction. Simultaneous use of probiotics on the basis of an intestinal stick in rations of chickens-broilers is the perspective directions. Proceeding from it, working out of new effective ways of increase of chickens-broilers efficiency with a view of reception of ecologically pure and safe products of poultry farming is actual for poultry-farming economy of Belarus.

Improvement of the standards of energy and protein diets of young stock cattle of 1-6 month old and determination of its influence on animal productivity was realized in the conditions of the Republic of Belarus. The studied made it possible to determine that at the age of 1 month the calf diet should contain 1,02 kg of dry matter and 21,2 MJ of metabolic energy; at the age of 2 months - 1,26 kg and 23,5 MJ; at the age of 3 months - 2,2 kg and 25,6 MJ; at the age of 4 months - 2,9 kg and 31 MJ; at the age of 5 months - 3,28 kg and 34,2 MJ; at the age of 6 months - 3,76 kg and 37,6 MJ, respectively. Metabolic energy concentration per 1 kg of dry matter should not be lower than 20,7 MJ at the first month, 19 MJ - at the second month, after the third month it should lower up to 10 MJ. In course of 6 months the presented diet scheme made it possible get 832 g of average weight gain in the conditions of forage expenses of 3,52 forage units per 1 kg

There was studied the width of distribution and peculiarity of clinical manifestation of mineral exchange diseases at pregnant sows, and also perfection of preventive actions at pathology of mineral metabolism in the conditions of prophylactic medical examination. Results of research have shown, that diseases of mineral metabolism widespread (84,7%) among pregnant sows in the conditions of industrial production, are most extended scarce conditions on Zn (17,7%) and Fe (22,5%). Clinically this insufficiency was expressed by oppression, appetite distortion, occurrence on a skin of specifically red stains correct roundish the form: with the clarified sites in the centre, are registered as abortions at final stages of pregnancy. It is established, that the way of preventive maintenance of hypomicroelementosis of pregnant sows with use of chelated forms of microelements is more preferable than sows, as reduces percent of clinical display of Zn and Fe deficiency, stabilize level of hematological and biochemical indicators of blood more effectively, and also raise industrial indicators of pregnant sows. | Целью работы было изучение широты распространения и особенностей клинического проявления заболеваний минерального обмена у супоросных свиноматок, а также совершенствование профилактических мероприятий при патологии минерального обмена веществ в условиях диспансеризации. Результаты исследований показали, что болезни минерального обмена веществ широко распространены (84,7%) среди супоросных свино¬маток в условиях промышленного производства, наиболее распространены дефицитные состояния по Zn (17,7%) и Fe (22,5%). Клинически эта сочетанная недостаточность выражалась угнетением, залеживанием, понижением и извращением аппетита, появлением на коже специфически красных пятен правильной округлой форма: с просветленными участками в центре, зарегистрированы так же аборты на конечных стадиях супоросности. Установлено, что способ профилактики гипомикроэлементозов супоросных свиноматок с использованием хелатных форм микроэлементов предпочтительнее, поскольку сокращает процент клинического проявления дефицита цинка и железа, эффективнее стабилизируют уровень гематологических и биохимических показателей крови, а также повышают производственные показатели супоросных свиноматок.

In the conditions of biogeochemical zone of the Republic of Belarus the most important role in mineral metabolism is played by such major mineral elements as calcium, magnesium, phosphorus, potassium and trace elements - cobalt, cupper, iron, iodine, zinc, manganese, and selenium. Based on the above there was determined the interrelation between the content of these minerals in fodder and blood of milking and dry pregnant cows. As a result of realized study it was found out that the content of major mineral elements and trace elements in fodder did not always correspond to their level in blood. In the conditions of insufficient supply of Ca, F, Mg, K, Fe, Си and Co in cow diets, the level of potassium in blood was lower standard and the other analysed minerals were within the standard limits. There was stated the direct correlation relationship between the level of some biochemical indices and content of mineral substances in cow diets. Positive correlation was stated between the content of calcium and magnesium and cholesterin level in blood

Analysis of the efficiency of application of fermented milk supplementary feed DKM (Belarus) produced on the basis of bacteria strain Lactobacilus acidophilus 55/06 in calve diets was realized in the conditions of the Republic of Belarus. Influence of feeding with acidified with the trial milk additive on forage palatability, biochemical blood structure and calve productivity was studied; economic efficiency of DKM use for processing of whole milk and its use in rations of calves was defined. Experimental batches of DKM fermented milk supplementary feed were produced at Grodno Medical Preparations Plant (Belarus). It was issued in the sterile corked polyethylene 5, 10 and 20 liter bottles or canisters. The fermented milk supplementary feed DKM could be stored at the temperature from 0 deg С up to 15 deg С. Shelf-life – 3 months from the moment of production. The additive represents the homogeneous mass of viscous consistence of cream color of various shades with a sour-milk smell. The carried out economic calculations showed, that as a result of growing capacity increase it animals of a trial group and reception of an additional total live weight gain there was stated the 6,5% decrease of expenses for fodder unit production in the experimental group. However, due to a high cost of acidified milk the cost of fodder unit in trial group was on 6,8% higher. As a result, the cost price of 1 kg weight gain in trial group (despite high additional weight gains) was stated at the level of control group. Application of fermented milk supplementary feed DKM in calve diets made it possible to lower calf disease incidence and to increase calf productivity on 11,8% without increasing the cost price of production

Balanced complete feeding proved to be one of the major conditions of animal productivity increase and improvement of their reproductive qualities. Full value of feeding could be obtained at the expense of forage quality improvement and perfection of structure of the rations providing the increasing of metabolic energy use by breeding bull-calves. Analysis of the efficiency of metabolic energy use by the replacement bull calves under conditions of various sugar and protein ratio was realized in the Republic of Belarus. Research results showed that enrichment of replacement bull calves (with 325-405 kg of live weight) rations with easy digestible carbohydrates (sugar and starch) in ratio of 32% from a dry matter ration, including 15% of stable starch made it possible to increase the transformation of metabolic energy into energy of body weight gain on 21,73 - 23,96 MJ or on 10,3%, that as a result correspondingly increased the daily average weight gains on 7,9% and reduced the expenses for forage energy for 7,1% counting on an energy unit. According to the ejaculate volume indices the bull calves of the second experimental group surpassed analogues of a control group on 14,8%, and according to sperm concentration indices - on 12%. The average quantity of the frozen doses of sperm has made 65%

There was developed a method of increasing the efficiency of used feeds and poultry productivity by means of stimulations of natural resistance of an organism by biologically active substances (Vigozin preparation, containing carnitine). Application of preparation Vigozin with potable water twice in a dose of 1 ml on 1 l of water within first 3 days and for 13th day of cultivation allows to raise safety of chickens-broilers on 2,3% at the expense of normalization of metabolism at young growth and preservation of a functional condition of a liver. Results of the general clinical and the immunological analysis of blood at chickens-broilers of control and trial groups (M+/-m, n=10), biochemical indicators of blood at chickens-broilers of control and trial groups in age dynamics (M+/-m, n=10) are presented. | Целью работы являлось научное обоснование и разработка способа повышения эффективности использования кормов и продуктивности птицы путем стимуляции естественной резистентности организма биологически активными веществами (препарат Вигозин, содержащий карнитин). Применение препарата Вигозин с питьевой водой двукратно в дозе 1 мл на 1 л воды в течение первых 3-х суток и на 13-й день выращивания позволяет повысить сохранность цыплят-бройлеров на 2,3% за счет нормализации обмена веществ у молодняка и сохранения функционального состояния печени. Представлены результаты общего клинического и иммунологического анализа крови у цыплят-бройлеров контрольной и опытной групп (M+/-m, n=10), биохимические показатели крови у цыплят-бройлеров контрольной и опытной групп в возрастной динамике (M +/- m, n=10).

The research directed on perfection of a cattle protein food system, taking into account its fractional structure, and also establishment of objective indicators of an estimation of forage protein nutrient density, have great value. It is established, that for young growth of cattle of 4-6 months of age the optimum parity of decomposable and un-decomposable protein in rations corresponds to size 68:32, allowed to raise digestibility of nutrients on 3-4%, nitrogen adjournment in an organism of animals on 10% and daily average a gain on 4% in comparison with parity 80:20. The optimum parity of fractional structure of protein makes positive impact on oxidation-reduction processes in organism to what testifies morphological-biochemical structure of blood. Thus concentration of crude protein raises on 1,7%, urea quantity decreases on 23%. The least cost price of a gain has appeared in group with a parity of decomposable and un-decomposable protein in rations 68:32, or it is better on 4,4% than an indicator of group with a parity 80:20%