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Administration of ochratoxin A and T-2 toxin to growing swine.
1994
Harvey R.B. | Kubena L.F. | Elissalde M.H. | Rottinghaus G.E. | Corrier D.E.
Effects of dietary ochratoxin A (OA) and T-2 toxin, fed singly and in combination, were evaluated in growing crossbred pigs. Thirty-six barrows (3 replicates of 3 for each of 4 treatment groups, mean body weight, 18.0 kg) were fed: 0 mg of OA and 0 mg of T-2/kg of feed (control); 2.5 mg of OA/kg of feed; 8.0 mg of T-2/kg of feed; or 2.5 mg of OA plus 8.0 mg of T-2/kg of feed for 30 days. Production performance, serum biochemical, hematologic, immunologic, and pathologic evaluations were made. Body weight and body weight gain were decreased by all toxin treatments, but the combination toxin treatment reduced weight gain more than did either of the toxins administered singly and could be considered additive. Liver weight was decreased by combination treatment, whereas kidney weight was increased by OA treatment. Ochratoxin decreased serum cholesterol, inorganic phosphorus, and alkaline phosphatase values; reduced mean cell volume, hemoglobin concentration, and macrophage phagocytosis; and increased creatinine and total protein values. Consumption of T-2 toxin reduced hemoglobin and serum alkaline phosphatase values. The combination treatment decreased serum cholesterol, gamma-glutamyltransferase, alkaline phosphatase, mean cell volume, hematocrit, and hemoglobin values, as well as lymphoblastogenesis and phagocytosis, and increased serum nine concentration. We concluded that OA and T-2, singly or in combination, can affect clinical performance, serum biochemical, hematologic, and immunologic values, and organ weights of growing barrows. Although some analytes were affected more by the combination than by either toxin alone, the interactions could best be described as additive, not synergistic.
Show more [+] Less [-]Ultrastructure of ostrich (Struthio camelus) spermatozoa. II. Scanning electron microscopy
1994
Soley, J.T. (Pretoria Univ., Onderstepoort (South Africa). Dept. of Anatomy) | Roberts, D.C.
Trypanosomes of some sub-Saharan birds
1994
Bennett, G.F. | Squires-Parson, D. (Newfoundland Memorial Univ., St. John's (Canada). International Reference Centre for Avian Haematozoa and Dept. of Biology) | Earle, R.A.
Immunohistochemical observations of proliferating cells in distal epiphyseal tissue of chicken femurs
1994
Kwak, S.D. | Kim, C.S. | Kang, C.B. (Gyeongsang National University, Chinju (Korea Republic). College of Veterinary Medicine)
Morphological studies on the hemal node in the Korean native cattle
1994
Yoon, Y.S. (Kangwon National University, Chuncheon (Korea Republic). Department of Veterinary Medicine)
Anatomical studies on pattern of branches of bile and hepatic ducts in Korean native cattle
1994
Kim, C.S. (Gyeongsang National University, Chinju (Korea Republic). College of Veterinary Medicine)
