A two-year old lioness (Panthero leo) was referred to our clinic with nasal and oral bleeding, vomiting and anemia. As being informed by the owner; we learned that the lion had a history of anorexia, nasal discharge, fatigue, dehydration and apathy just one month prior to admitting the clinic. At the laboratory examination Urea, Creatinine and RBC (red blood cell) were higher than normal. Coronavirus, Feline Leukemia Virus, Feline Immunodeficiency Virus (Rapid FIV/Ab FeLV Ag Test Kit, Bionote®) agents were checked with commercial immunochromatographic rapid test kit and found as negative. Heamobartonella sp was found by blood smear. Enrofloxacin (Baytril-K % 5, Bayer®) 10 mg/kg dose for 10 days once a day and vitamin K and supportive fluid were given for treatment. All clinical signs and abnormal blood values returned to normal levels after 17 days. This report indicated that Heamobartonella sp is important agent also for wild cats and all cats should be controlled for this to infection even if suffered from renal failure.