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Determination of macrophage chemotaxis to atherosclerotic plaque extract in domestic turkeys with hypertension
1990
Johnson, P.D. | Klesius, P.H. | Krista, L.M.
The chemotactic activity of turkey peritoneal macrophages in response to an atherosclerotic plaque extract from a hypertensive strain of turkeys was determined. Atherosclerotic plaque extract stimulated macrophage chemotaxis, whereas normal aortic extract did not stimulate macrophage chemotaxis. However, differences were not revealed by sodium dodecyl sulfate-polyacrylamide gel electrophoretic analysis of extracts of atherosclerotic plaque and normal aorta. Chemotactic activity was diminished with pronase treatment, suggesting the chemoattractant is a protein. Seemingly, atherosclerotic plaque of turkeys contains a macrophage chemotaxin.
Show more [+] Less [-]Studies on the laboratory animal modelling of atheroosclerosis and the preventive mechanisms of dietary fiber against atheroosclerosis
1993
Kim, H.W. | Lee, Y.S. | Lee, H.S. | Shin, K.S. | Lim, C.H. (Seoul National University, Suwon (Korea Republic). College of Veterinary Medicine)
