In the conditions of the Republic of Belarus there was created an adhesive antigen on the basis of bacterial suspension of Escherichia which were separated from culture media by means of purification and concentration on membranes UMP-300 and UMP-5 that made it possible to obtain a cleaned-up preparation the specific activity of which was in 2-4 higher that of the unpurified one. In course of the study there was developed a method of purification and concentration of adhesive Escherichia antigens with the help of membrane technology. There were obtained biologically active adhesive antigens E.coli K88, K99, F41, 987P; there were selected the ultrafiltration membranes providing the optimal selectivity and productivity of the process; there were studied the influence of some factors on the process of adhesins concentration by means of ultrafiltration method. During the experiments there was analysed the agglutinating activity of antigents prepared by different methods.

In the conditions of the Republic of Belarus there was studied the application of sodium chloride obtained by electrolysis method on Akvamed installation in a complex of activities for the preventive measures of animal helminthoses. Electrochemical activation of aqueous solution of sodium chloride proved to be a progressive and rational technology which made it possible to substantially reduce the material costs and power consumption for the development of highly efficient and ecologically safe disinvasion solution. Application of sodium chloride solution with the minimal content of available chlorine of 3,0 g/l provided the death of 94-95% of Taeniidae eggs in course of 30 minutes after applicated of the preparation on the treated surface. The proposed method can be recommended as the most efficient and economically effective for the disinvasion of external environment.

In the conditions of the Republic of Belarus there was analyzed fauna of parasites of gastro-intestinal tract and natural resistance of horses in the conditions of Polesye State Radiation Ecological Reserve. There were worked the most efficient antihelminthic compounds. Analysis of helminthological state showed that extensiveness helminthic and gastrophilosis invasion of horses was at a high level. In this regard the nematodosis and gastrophilosis (Gastrophilus intestinalis) invasions prevailed. In mature and growing horses there was marked the dominance of nematode worms of Strongylidae / Trichonematidae families (78,9-83,8%) and Gasterophilidae (95,8%). Next, at growing horses there were stated nematodes Strongyloides westeri and cestoid worms of Anoplocephalidae family, at mature horses – of Gasterophilidae, Parascaris equorum and Oxyuris equi families. The following antihelminthic compounds ans preparations showed the best efficiency: Univerm; Avermektin paste 1%; Fenbendazoli, Rivertin 1%.

In the conditions of the Republic of Belarus there was analyzed the influence of inclusion into broiler chickens diets of probiotoc preparation Bifidoflorin zhidkij (liquid) and prediotic veterinary drug Biofon AIL on the natural resistance, hematopoiesis, growth, metabolic function, development and viability of broiler chickens. In course of the study there was analyzed the dynamics of total haemoglobin, total protein of blood serum, albumins and globulins of broiler chickens which were fed with veterinary drugs probiotoc Bifidoflorin zhidkij and prediotic Biofon AIL. Indexes of chicken viability and life weight gain were marked. Research results showed that application of the presented veterinary preparations rendered the growth promoting action, lowering of disease incidence, increasing of chicken viability, increasing of live weight gain and stimulation of metabolic processes in the most intense period of poultry growing. All these factors were expressed in highest degree after the combined application of the probiotic and prebiotic veterinary drugs.

In the conditions of the Republic of Belarus there was determined the therapeutic efficacy of combined application of a complex antibacterial veterinary drug (containing lincomycin and spectinomycin) and Trivitim for the treatment of calves with respiratory diseases. In course of the study of 12 1-1,5 month old calves with respiratory diseases there were analyzed the hematological blood indexes, white blood cell differential and content of total protein in blood serum before the beginning of treatment and on the seventh and fourteenth days after beginning treatment. Research results showed that application the antibacterial veterinary drug in complex therapy with Trivitim in treatment of calves proved to be efficient. Their administration shortened the terms of recovery and prevented animal death as well as promoted the normalization of hematological and biochemical blood indexes.

In the conditions of the Republic of Belarus there was studied the influence of methods and means of spot heating and localization of warmth on indexes of microclimate in piglet breeding houses and resting area of piglets and their growth parameters. In course of the study there taken into consideration the indexes of an average temperature on piglet resting area housings; atmosphere relative humidity, air velocity, content of carbon dioxide, content of hydrogen nitride in the housing and resting areas of piglets. Research results of microclimate of swine breeding areas and resting areas of piglets under different means and methods of heating and warmth localization showed that the it was the most efficient to add for the local heating in the first three weeks of suckling period the glow-discharge tubes or in suckling period or weanling periods - the heated floors; and in suckling period - brooders in the form of tops with shields.

In the conditions of the Republic of Belarus there was studied the morphology and growth dynamics of vomeronasal cartilage of swine at postnatal period. The vomeronasal cartilage covers the vomeronasal body outside. Lateral and medial bases of vomeronasal cartilage formed an antrum in which there was an organon vomeronasal. The most intensive growth of a cartilage of pigs occurred in the first two months of animal life. Arrangement of cartilage was dissymmetric - at the right it was sited more caudad than at the left; this fact caused the differences in its dimensions at the transverse sections.

In the conditions of the Republic of Belarus there was analyzed the efficiency of application of organic form of selenium Sel-plex in feeding of producer bulls. In course of the study there was showed the dynamics of live weight and average daily weight gain of producer bulls; blood indexes of analimals by the end of the experiment; sperm quality of experimental bulls. As a result of research it was established, that application of organic form of selenium Sel-plex in feeding of breeding bulls during the summer and winter periods in a dose of 0,4 mg/kg of dry matter of a ration promoted the increasing of daily average live weight gain on 6,4-8,1%, improvement of morphological and biochemical blood structure, increasing of indices of natural resistance on 0,5-6,1% and sperm production quality - on 7,3-28,0%.

In the conditions of the Republic of Belarus there was analyzed the influence of the following paratypical factors on cow productive longevity: age of the first calving; milk yield at the first lactation; and a birth season. At the experimental animals there studied the indices of dairy efficiency: a lifelong milk yield (kg); a lifelong yield of dairy fat (kg); the total duration of the lactation period (days); duration of practical use (lactations). There was noted a tendency of increasing of a term of productive use and lifelong productive efficiency at the animals the practical economic use of which was begun in later terms. The insemination of these animals was approximately realized at the age older than 21 months. Also it was stated that in accordance with all investigated indices (except for a milk yield per one day of lactation) the highest indexes were typical for cows which had the least milk yield at the first lactation.

In the conditions of the Republic of Belarus it was determined that application of monocalcium phosphate in a dose of 10 gram per 1 kilogram of mixed fodder and specified doses of trace elements (cuprum; zink; cobalt; manganese; iodine) in diets of growing pedigree bull calves made it possible to increase indices of body weight of young cattle stock of the third experimental group in comparison with animals of the first and the second groups on 18,3 and 11 kg or respectively on 3,9 and 2,3%; as well as to increase the intensity of their growth. The highest daily average live weight gain was noted at animals of the third experimental group – 1062 grams. It was higher than at bull calves of the first and the second groups respectively on 31,3 and 12,8 grams, or on 3 and 1,2%. Application of monocalcium phosphate in a dose of 10 gram per 1 kilogram of mixed fodder favorably affected the formation of desirable type of sexual behavior and indices of semen production quality. Thus, in the third experimental group in comparison with animals of the first and the second groups the volume of ejaculate was on 0,2 and 0,1 ml higher (or on 5,8 and 2,9%); quantity of sperm in ejaculate - on 0,7 and 0,3 billion, or on 35 and 15%.