For the determination of efficiency of a new produced in the Republic of Belarus preparation Ehkvikar there was modeled a test with a diaphoresis of guinea pigs by means of their staying in a thermostat at a temperature of 45-50 deg C in course of 30 minutes. Before and after the test there was taken a blood test for its analysis. Results of the experiment showed that together with sudo the animals lost 1-2 % of their body. There was stated the increasing of all blood corpuscles as well as lowering in 1,3-1,47 times of such elements as chlorine, sodium, potassium, and also T lymphocytes and bursa-derived lymphocytes. Application Ehkvikar promoted the stabilization of biochemical and morphological parameters of blood, and also the immune status of laboratory animals. Thus, Ehkvikar preparation promoted the compensation of losses of electrolytes with sudor of guinea pigs and in future can be studied by an example of horses for completion of electrolytes losses in the conditions of increased physical exercises.

Division of selection area at rest and feeding areas and setting the straw bedding norms for heifers of 6-12 months of age as 2 kg per animal daily, 13-16 months of age – 3 kg and 17-25 months of age – 4 kg promotes increases of average daily live weight gains compared to traditional technological solutions and norms at 6,4%, hemoglobin content – at 3,7%, erythrocyte quantify – at 5,6%

Data on studying of efficiency of application of immunobiological preparations on efficiency and other clinical and biochemical indicators for chickens-broilers are cited. It is established, that their application to chickens-broilers promotes increase of biological value of fowl as foodstuff and is economically expedient. Application of a preparation the Biococktail-NK in an optimum dose 0,1 - 0,2 ml/goal (10,0-20,0 million microbic bodies) has allowed to increase intensity of growth of chickens-broilers by 3,5%, to lower forage expenses for production of a gain of body weight of 1 kg on 4,95%, to raise safety of young growth of birds on 3,4 % and to lower a case of birds to 1,6% (technological norm of 5%). The carried out calculations have shown, that introduction of the Biococktail-NK in a ration of broilers is economically justified, as safety of young growth in 4th trial group has raised on 3,4%, in the third - on 2,5%, in the second - on 1,3%. On the basis of the spent research fowl of the delivered samples in which ration it was entered the probiotic Biococktail-NK from calculation 0,1 - 0,2 ml/goal (10,0-20,0 million microbic bodies) since daily age within the first 5 days into 4 cycles with an interval of 7 days till the end of the cultivation period is established, that on organoleptic, physical and chemical, bacteriological indicators, and also biological value and harmlessness does not concede to meat of control group and is good-quality. In the literature there are data about influence of biologically active substances on growth and development of bird. Despite it, about influence of probiotical and immunostimulatory preparations as separately, and in a complex with probiotics, on an organism of chickens-broilers it is not enough data that induces carrying out of scientific research in the given direction. Simultaneous use of probiotics on the basis of an intestinal stick in rations of chickens-broilers is the perspective directions. Proceeding from it, working out of new effective ways of increase of chickens-broilers efficiency with a view of reception of ecologically pure and safe products of poultry farming is actual for poultry-farming economy of Belarus.

Comparative evaluation of the influence of cell-free probiotic preparation Laktimet and cellular probiotic Bifilak on productivity, livability, nonspecific response of suckling piglets in the early extrauterine life was realized in the conditions of the Republic of Belarus.Application of both probiotics increased the productivity of suckling pigs, stimulated the processes of metabolism and natural protection of organism in the early postnatal period in the conditions of specialized pig breeding complexes. Research results showed, that application of brand new cell-free probiotic Laktimet exercised higher influence on suckling pigs. Application of Laktimet made it possibler to increase piglets body weight gain on 7,8%; piglet livability - on 6,7%; and application cellular probiotic preparation Bifilak - on 5,4% and 3,3%, respectively. The same tendency was noted during the analysis of indexes of cellular factors of organism protection. Bactericidal activity of blood serum of experimental animals changed both in connection with age, and under influence of probiotic preparations. During all studied periods the bactericidal activity of blood serum was authentically (P less than 0,05) above in experimental groups in comparison with a control group. At 20-days old piglets there was stated the strengthening of bactericidal activity of blood serum. Throughout all period of experiment the superiority of trial animals over control on indicators of lysozyme activity of blood serum was observed

The effectiveness of stress prevention with use of sedative remedy Xyla in a complex with preparations Ascorbic acid with glucose, Aesel and Katosal, which improve adaptation, was researched. Application of a complex of neurotropic and adaptogenic preparations before and after dehorning promoted softening of stressful influence, that in turn has positively affected the general condition of animals and intensity of growth. Comparative test of four schemes of preventive maintenance of negative consequences of the stress caused calf dehorning, has shown their high efficiency. However more expressed stimulating influence on intensity of metabolism, antioxidant status, natural resistance, adaptation to action of stresses-factors and rates of a body weight gain were rendered by the scheme with use of preparations Aesel, Ascorbic acid with glucose and Ksila

The purpose of the research was establishment of hepatic diseases spread in cattle fattening. Trials were conducted with total number of hybrids IV-V generation of black-motley heifer with pedigree Hereford bulls. It has been established the wide spread (22,4%) of hepatic pathology. The leading place among all hepatic pathologies belongs to fatty hepatosis (13,4%) with weakly expressed symptoms, decrease of serum protein level, albumin, glucose and increase of bilirubin, globulins, hepatic enzymes and strong pathology-anatomical and histological manifestations. In the tabular form results of histologic research of liver, some biochemical indicators of blood of healthy and sick animals (M +/- m), the clinical symptoms revealed during the various periods are resulted | Целью исследований являлось изучение структуры и установление широты распространения болезней печени у крупного рогатого скота на откорме. Опыты проведены на широком поголовье помесей IV-V поколения тёлок чёрно-пёстрой породы с племенными быками герефордской породы. Установлено широкое (22,4%) распространение гепатопатий. Ведущее место среди различных форм поражения печени принадлежит жировому гепатозу - 13,4%, морфофункцинальный профиль которого определяется слабо выраженными клиническими симптомами, уменьшением уровня общего белка, альбуминов, глюкозы, повышением концентрации билирубина, активности гепатоспецифических ферментов, а также всех фракций глобулинов, яркой и характерной патологоанатомической и гистологической картиной. В табличной форме приведены результаты гистологического исследования печени, некоторые биохимические показатели крови здоровых и больных животных (M +/- m), клинические симптомы, выявленные в различные периоды

In the conditions of the Republic of Belarus there was realized the determination of efficiency of application of saline and chelate forms of copper and cobalt for treatment of anemic syndrome of cattle. It was found out that lack of copper and cobalt in cattle diets in the conditions of normal supply of iron could be a cause of cattle anemic syndrome. It took place because of the iron adsorption disorder in intestines and its inclusions in haem, as well as lowering of ehritropoztin synthesis. In the conditions of administration of copper and cobalt-containing preparations for animals there was noted the increasing of iron and haemoglobin content in blood. Administration of ethylene diamine tetraacetates of cobalt and copper made it possible to reduce considerably all evidences of clinical and laboratory symptoms of anemia and hypomicroelementosis in comparison with application of copper sulphate and cobalt.

In the conditions of the Republic of Belarus there was realized comparative evaluation of chemical composition and nutritive value of silages produced on the basis of millet (Panicum) and maize (Zea mays), their productive action and economic efficiency of ensilage fodders in diets of young stock of cattle. Data of chemical analysis showed the benefits of millet silage. The content of crude protein, crude fat, carotene, calcium and phosphorous was higher in millet silage. The analogous situation was in the analysis of biochemical indexes and energy value of dry matter. As a result of application of millet silage in diets of young stock of cattle made it possible to obtain 3,7 kg of body weight gain, while the expenses of forage per 1 kilogram of of weight gain lowered on 0,34 centner of fodder units, or 3,6%. Prime cost of 1 centner of fodder units in a diet in experimental group was on 57,3% lower than in a control one. Thus, use of millet silage in diets of heifers made it possible to lower the cost of fodders per 1 kilogram of weight gain on 63,2%, and prime cost of 1 kilogram of weight gain – on 19,8%.

Scientific and production examination of feed additive Semerik-Vita containing iodine and selenium was realized in the conditions of the Republic of Belarus by studying of its influence on production and economic indexes of laying hens and their products, as well as by studying of its influence on clinical state and biochemical blood indexes of poultry. Research results showed that application of feed additive Semerik-Vita made it possible to increase of egg producing ability intensity on 1,8 %, egg yield - on 2,4 % in the conditions of lowering of feeding expenses on 1,4 %. Application of the analyzed feed additive made it possible to obtain a new kind of eggs fortified with iodine, selenium, beta-carotene and vitamins (A, E, C, PP, B1, B2, pantothenic acid and folic acid). In eggs of poultry of experimental group the content of selenium increased in 2,1 times, iodone - in 1,5 times, vitamin E – in 3,9 times, beta-carotene – in 1,4 times, vitamin A – in 1,3 times, pantothenic acid – in 1,2 times, vitamin C – in 1,17 times, vitamin PP – in 1,4 times, vitamin B1 – in 1,5 times, vitamin V2 – in 1,4 times, folic acid - in 1,5 times in comparison with eggs of laying hens from the control group. Research results proved that application of Semerik-Vita did not render negative effect on the clinical indexes of laying hens. It made it possible to lower the content of urea acid in 1,7 times, as well as to increase the content of triglycerides in 2 times, cholesterol - in 2,4 times, magnesium - in 1,28 times

Research of immune activity of an experimental series of inactivated vaccine against swine pasteurellosis (Pasteurella) with application of adjuvants of Sepptic Montanida ISA 70 and Montanida ISA 206 was realized in the conditions of the Republic of Belarus. In the capacity of water phase there were used serovars A, B, and D Pasteurella multocida. Research results proved the possibility of application of adjuvants of Sepptic company for the development of vaccine against pasteurellosis. The vaccine with the presented adjuvants after its application did not cause after-trouble effects. In course of immunization there was noted the formation long-lived continuous immunity that was proved by high titres of specific anti-bodies in blood serum in all experimental groups of piglets. Single application of the proposed vaccine in doses 2 or 3 ml per animal proved to be effective. Also it was efficient to apply it twice in doses 1 and 2 ml per animal. For the vaccine production it was proposed to use adjuvant Montanida ISA 206 which did not have high reactogenicity