BACKGROUND: Abomasal hypomotility plays an important role in pathogenesis of some abomasal disorders such as abomasal bloat which has the same serious side effects associated with using synthetic drugs for its treatment, such as diarrhea and antibiotic resistance. To decreasing these side effects, administration of herbal medicine is a good way. OBJECTIVES: To determine the effect of oral administration of turmeric aqueous extract on rate of abomasal emptying rate in neonatal lambs. METHODS: This study was conducted on twelve five-day-old Sangsari-female-lambs (average weight 3 kg). All lambs received five oral treatments, including saline (30 ml), erythromycin (400 mg), turmeric 200 mg/kg, turmeric 250 mg/kg, and turmeric 300 mg/kg, respectively. At 0, 30, 60, 90, 120, 150, 180, and 240 minutes after each treatment, plasma samples of lambs were taken. The rate of abomasal emptying was determined with acetaminophen absorption test. RESULTS: Treatment with erythromycin and three different doses of aqueous extract of turmeric (200, 250, 300 mg/kg) increased the rate of abomasal emptying in comparison to the negative control treatment, significantly (P<0.05). The stimulatory effect of erythromycin on abomasal emptying was higher than aquatic extract of turmeric, significantly (P<0.05). No clinical side effects were observed following the administration of erythromycin and turmeric in lambs. CONCLUSIONS: This study showed that aqueous extract of turmeric has a stimulatory effect on lamb's abomasal emptying but more studies are needed on the effect of this plant’s components on abomasal emptying.

This study was designed to find out the effect of oral inoculation of aqueous extract of Curcuma Longa at two doses (1 and 5) mg/ kg body weight daily for 4 weeks on the immune response of Balb/c mice by estimating of serum concentration of interleukin-2 (IL-2) , interleukin-4 (IL-4), interleukin-10 (IL-10) and interferon gamma (INF-γ) using ELISA test. The present results revealed that significant increase (p

The aim of the current study was to evaluate the effect of different levels of Curcuma longa on some physiological and biochemical parameters, as well as some egg productive and quality characters and the intestinal microflora of local quail. 240 one-day-old quail were distributed randomly into 4 groups (60 birds/group) with 3 replicates. The groups were as follows: 1st group (control) birds were reared on standard ration, the 2nd, 3rd and 4th groups birds were reared on standard ration supplemented with 3, 6 and 9 gm turmeric/kg ration respectively. The results revealed that the turmeric improve blood picture as represented by the significant increase of RBCs, Hb and PCV% specially in 3rd and 4th treatments. Also, the turmeric reduced significantly triglycerides and cholesterol compared with the control. Curcuma longa treatment improved the intestinal microflora represented by the significant decrease in the number of pathogenic flora (Salmonella and E. coli), and significant increase in the benefit flora (Lactobacillus). On the other hands treatments reduced significantly the age of 1st egg production and enhance the age of 50% egg production. In conclusion, Curcuma longa treatment induced ameliorative effects on some of physiological and productive performance of quail.

Objective: This study aimed to investigate the impact of thioacetamide (TAA) on the structure and function of the testes and assess the therapeutic effects of Curcuma longa (Cl) against TAA-induced toxicity in rats. Materials and Methods: Thirty-two male albino rats weighing 180–200 gm and aged 11–12 weeks were randomly separated into four groups. The control group was given normal saline, the Cl group was orally administered Cl (500 mg/kg/day), the TAA group received intraperitoneal TAA (200 mg/kg body weight, three times/week), and the Cl with TAA group received Cl orally two hours before TAA administration. After 8 weeks, all rats were anesthetized, and body and testis weights were recorded. Morphological and histological assessments as well as biochemical analyses were conducted. Results: The study revealed a significant decrease in both body and testis weights in the TAA group, accompanied by a substantial increase in luteinizing hormone (LH), follicle-stimulating hor¬mone (FSH), and malondialdehyde (MDA) levels. Testosterone (T) and glutathione (GSH) were significantly decreased in the TAA-treated group compared to the control. Conversely, the Cl-treated group exhibited a substantial decrease in LH, FSH, and MDA levels while showing a significant increase in T and GSH. Conclusion: Cl has been found to have a potential therapeutic role in mitigating TAA-induced testicular damage by acting as an antioxidant. This is supported by a significant decrease in oxi¬dative stress markers and supporting hormonal levels. Further research is needed to understand the underlying mechanisms and explore the clinical applicability of Cl in preventing and treating testicular toxicity. [J Adv Vet Anim Res 2024; 11(3.000): 762-771]