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Treatment of selected canine dermatological conditions in Portugal – a research survey
2018
Oliveira, Ana | Devesa, Joana S.P. | Hill, Peter B. | Silva, Vanessa | Poeta, Patrícia
Introduction: Staphylococcus pseudintermedius and Malassezia pachydermatis often cause skin diseases in dogs. Material and Methods: An online survey was e-mailed to veterinary practices nationwide covering demographics, diagnosis methods, and oral and topical treatment options. Of the 740 surveys sent, 100 complete replies were obtained. Results: The majority of clinicians were unaware of the existence of the International Society for Companion Animal Infectious Diseases guidelines or did not follow them (53%). Oral antibiotics were used universally for superficial bacterial folliculitis treatment, particularly amoxicillin-clavulanic acid (100%), cephalexin (94%), enrofloxacin (67%), or marbofloxacin (60%). For fold dermatitis (FD) and otitis externa (OE), oral antibiotics were also given as treatment in 88% and 82% of cases, respectively. Oral antifungals were often prescribed for generalised Malassezia dermatitis (85%), FD (70%), and OE (59%). S. pseudintermedius and M. pachydermatis were frequently treated topically, particularly with antibacterials or antifungals only, or a combination of antibacterials, antifungals, and glucocorticoids. Alternative options such as honey-based products were not frequently used. Conclusion: Our survey suggests that oral antibiotics are overused by Portuguese clinicians despite the spread of antibiotic resistant S. pseudintermedius. Oral antibiotics and antifungals are commonly prescribed for skin conditions manageable with topical treatments.
Show more [+] Less [-]Effects of short-term anti-inflammatory glucocorticoid treatment on clinicopathologic, echocardiographic, and hemodynamic variables in systemically healthy dogs
2018
Masters, Allison K. | Berger, Darren J. | Ware, Wendy A. | Langenfeld, Natalie R. | Coetzee, Johann F. | Mochel, Jonathan P. M. | Ward, Jessica L.
OBJECTIVE To investigate mechanisms by which anti-inflammatory doses of orally administered intermediate-acting glucocorticoids (prednisone) could predispose dogs to progression of heart disease or congestive heart failure. ANIMALS 11 client-owned dogs with allergic dermatitis and 11 matched healthy control dogs. PROCEDURES Clinicopathologic, echocardiographic, and hemodynamic variables were measured. Dogs with allergic dermatitis then received prednisone (1 mg/kg, PO) once daily for 14 consecutive days beginning on day 0 (baseline), followed by a tapering and washout period; control dogs received no treatment. Measurements were repeated on days 7, 14, and 35. Linear mixed modeling was used to compare changes in variables across measurement points and between dog groups. RESULTS Prednisone administration caused no significant changes in serum sodium or potassium concentration, blood glucose concentration, or target echocardiographic variables. The change from baseline in systolic arterial blood pressure at day 7 was significantly greater in prednisone-treated dogs than in control dogs. Expected changes in hematologic and serum biochemical values with prednisone administration (neutrophilia, eosinopenia, isosthenuria, and high serum alkaline phosphatase and alanine aminotransferase activities) also occurred in the prednisone-treated dogs. CONCLUSIONS AND CLINICAL RELEVANCE Findings suggested that anti-inflammatory doses of orally administered glucocorticoids have the potential to adversely impact cardiac function in dogs by causing an increase in blood pressure and thus increased cardiac afterload.
Show more [+] Less [-]Malassezia spp. Overgrowth in a Chinchilla Cat
2018
Comak, Cansu | Ceylan, Ebubekir
Malassezia spp. is a commensal yeast organism that is a normal resident of the skin, mucosa, and ear canals. A castrated male, 4-year-old Chinchilla cat, was brought with hair loss and skin lesions on ears, face and arms. Skin scrapings were collected from the lesions. Terbinafine HCl (30 mg/kg, PO), Omega 3 and Omega 6 essansial fatty acid supplement (Megaderm®, Virbac) were administered to the patient.
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