The spectrum of acaricides changes continuously and improves. At the same time, big attention is given to research of new, more effective preparations meeting modern requirements. Research on studying the efficiency of Akaribil preparation against swine sarcoptosis (Sarcoptidae) was realized in the conditions of swine breeding farm in the Republic of Belarus. The preparation possesses high insect-acaricidal activity. In the conditions of the preparation storage and repeated opening of a ware in the course of tests there were stated no changes in drug smell or color. The scheme of the preparation application is applied in industrial production technology. It possesses anti-inflammatory properties, antiseptic stimulating healing of skin damages, does not irritate integuments, renders weak irritating effect on mucous membranes of eyes. In recommended doses Akaribil does not cause any adverse effects and complicating disease. There were stated no contraindications to preparation application. High therapeutic efficiency against arachnoentomosis was proved. Application the preparation made it possible not only to reduce disease incidence and animal death, but also to facilitate the severity of scabietic diseases. As a result of realized research it was established that efficiency of Akaribil against swine sarcoptosis was 100%.

In the conditions of the Republic of Belarus there was realized a complex of studies of quality swine slaughter products against the background of combine applications of the albuminous-vitamin-mineral additive Immovit and an extract of hill-growing saltwort for the preventive maintenance and treatment of a toxic dystrophy of liver. Research results showed the analysed preparations did not render negative influence on quality and safety of produced meat products. Against the background of application of the albuminous-vitamin-mineral additive Immovit in combination with an extract of hill-growing saltwort there was stated the improvement of swine slaughter product quality. In products from the animals which were administrated with a complex of examined preparations there was stated an optimized moisture content, the increasing of a relative biological value of a product (101,3-103,8%), and according to the indexes of bacterial safety the experimental pork considerably surpassed the meat indexes from animals of control groups. At the same time, in slaughter animal products of control groups there were revealed coliform bacillus bacteria.

In the conditions of the Republic of Belarus there were studied the aetiology factors in development of dermatoses of productive cows taking into account the hygienic aspects. Structural defects of floors of cattle livestock buildings in animals of an experimental group promoted higher (on 35%) development of mattery dermhelminthiasis of distal areas of hindlegs in comparison with animals of a control group. Occurrence of skin dermhelminthiasis, especially in distal areas of hindlegs, was caused by various primary traumas of soft parts with the subsequent introduction into them of pathogenic microbial flora. The imperfect design of floors, an unsatisfactory microclimate in cow cattle houses, hypodynamia in the absence of constitutional walk made the preconditions for it. The reasons of purulent dermatosis of cows were two interconnected etiological factors: mechanical damages of tissues and development of a surgical infections in affected areas against the background of unsatisfactory microclimate that led to decrease in dairy efficiency on 4,51%. Therefore in a complex of the actions directed towards the preventive maintenance of surgical diseases, it is necessary to include the strict control over designing, building and operation of cattle-breeding premises, traumatism prevention, creation of an optimum microclimate and observance of zoohygienic norms of cattle maintenance.

In the conditions of the Republic of Belarus taking into consideration the hygienic aspects there were studied the aetiological factors in dermatosis development in productive cows. As a result of realized research it was established that aetiology of skin diseases in the area of a mammary gland were traumas, and following affects were more often marked: skin rhagades of mammillars; wound in the area of a mammary gland and mammillars; fistulas of milk tank vessels; and also sporadic damages of sphincter muscle of teat canal caused by machine milking. This in its turn gives made it possible to consider, that traumas of various character were a contributing factor for occurrence of udder garget - mastitis. In course of the realized analysis there was proved a high therapeutic efficiency of 1% aethonium gel for the treatment of various traumas of mammary gland and udder mammillars of cows. Clinical recovery of animals after administration 1% aethonium gel was stated on 3,2 days earlier, than after administration of Burenushka cream in the postoperative period. Healing and restoring action of 1% aethonium gel for udder tissues was proved by changes in number of somatic cells in milk. The quantity of somatic cells in 7 days after administration of 1% aethonium gel came back to the level which was typical healthy animals, while in the control group the quantity of somatic cells per 1 ml of milk did not decrease essentially.

In the conditions of the Republic of Belarus there were determined the parameters of acute and subacute toxicological characteristics of the developed in the Vitebsk State Academy of Veterinary Medicine anthelmintic preparations of durable action Febolvetum-О for control of sheep strongylatosis and Febolvetum for control of strongylatosis of cattle young stock. Data on determination of toxicological parameters of the prolonged action bolus were presented. Research results showed that the preparations did not render negative influence on laboratory animals (white mice). According to the parameters of acute oral toxicity the Febolvetum was qualify as the third hazard class. In accordance with the results of study of subacute toxicity parameters of the preparations, it was concluded, that in the conditions of free feeding of Febolvetum boluse in combination with forages in course of 30 days in doses of 200 mg/kg; 150 mg/kg; 100 mg/kg of body weight in animals there were found no signs of intoxication; there were not stated any is not fixed deviations in physiological state; and were stated no mice death.

In the conditions of the Republic of Belarus there was studied a comparative efficacy of methods of drug administration for diseased animals with respiratory diseases. It was stated that enteral (internal) administration of Tromexin in a complex therapy of calves with respiratory pathology possesses rendered low therapeutic efficacy and could have a lethal outcome. Parenteral (intramuscular) administration of Enrotil and Dexafort for a complex therapy of calves with respiratory pathology rendered a moderate therapeutic efficacy and could lead to animal's state improvement. Parenteral (intravenous) administration of hypertonic solutions of norsulfazol, calcium chloride, sodium chloride and glucose in complex therapy of calves diseased with a respiratory pathology proved to render a high therapeutic efficacy and may lead in a complete clinical recovery.

In the conditions of the Republic of Belarus there was studied the influence of various doses of dolomite on productivity, egg quality and a mineral metabolism of laying hens. The research was realized by an example of laying hens of Highsex Brown. The experimental hens at the age of 250 days old were divided into 4 groups on 60 heads in each by means of analog method. Laying hens of the first (control) group were fed with a basic diet including 5% of a soya cake (cockle-shell), and hens of the second, third and fourth (experimental) groups instead of a soya cake were fed with a mixed fodder with addition of a mineral additive of dolomite. Hens of the second group were fed with the additive at a rate of 2%, the third group - 3%, and the fourth group - at a rate of 5% of weight of dry matter of forage. During the experiments there were maintained optimum parameters of microclimate, recommended temperature and light regimes and a sufficient ultra-violet irradiation. As a result of the realized research it was established, that use of the mineral dolomite additive in feeding of laying hens proved to be possible as a substitute of an expensive import cockleshell. Use of various doses of dolomite promoted improvement of mineral metabolism, increasing of productivity and improvement of egg quality of laying hens.

In the conditions of the Republic of Belarus there was analyzed the efficiency of application of organic form of selenium Sel-plex in feeding of producer bulls. In course of the study there was showed the dynamics of live weight and average daily weight gain of producer bulls; blood indexes of analimals by the end of the experiment; sperm quality of experimental bulls. As a result of research it was established, that application of organic form of selenium Sel-plex in feeding of breeding bulls during the summer and winter periods in a dose of 0,4 mg/kg of dry matter of a ration promoted the increasing of daily average live weight gain on 6,4-8,1%, improvement of morphological and biochemical blood structure, increasing of indices of natural resistance on 0,5-6,1% and sperm production quality - on 7,3-28,0%.

In the conditions of the Republic of Belarus it was determined that application of monocalcium phosphate in a dose of 10 gram per 1 kilogram of mixed fodder and specified doses of trace elements (cuprum; zink; cobalt; manganese; iodine) in diets of growing pedigree bull calves made it possible to increase indices of body weight of young cattle stock of the third experimental group in comparison with animals of the first and the second groups on 18,3 and 11 kg or respectively on 3,9 and 2,3%; as well as to increase the intensity of their growth. The highest daily average live weight gain was noted at animals of the third experimental group – 1062 grams. It was higher than at bull calves of the first and the second groups respectively on 31,3 and 12,8 grams, or on 3 and 1,2%. Application of monocalcium phosphate in a dose of 10 gram per 1 kilogram of mixed fodder favorably affected the formation of desirable type of sexual behavior and indices of semen production quality. Thus, in the third experimental group in comparison with animals of the first and the second groups the volume of ejaculate was on 0,2 and 0,1 ml higher (or on 5,8 and 2,9%); quantity of sperm in ejaculate - on 0,7 and 0,3 billion, or on 35 and 15%.

In the conditions of the Republic of Belarus there was analyzed the productivity of 13-18-month old young stock of cattle which was bred for meat with various levels of energy value nutrition. Also, there were noted their slaughter qualities and chemical composition of meat. Administration of diet rations with an increased level of exchange energy and the best indices of protein fissility rendered a positive influence on productivity of young stock of fattening cattle and made it possible to obtain 1103-1100 gram of body weight gain. As a result, the energy value gain was 22,9-22,6 MJ along with conversion of metabolizable energy at a gain - 24,7-25,3%. Consumption of metabolizable energy per 1 MJ along with body weight gain were within 4,7-5,0 MJ. Feeding of rations with various levels of the studied factor rendered the positive influence on slaughter qualities, made it possible obtain slaughter yield of 53,6-54,6% at an optimum ratio of nutrients in meat. Feeding of bull calves with diets with excessive content (up to 10%) of metabolizable energy made it possible to lower the prime cost of obtained breeding products on 0,55%.