The present study was conducted on six crossbred calves below one year of age. The lead acetate was given @ 25 mg/ kg body weight orally for 7 days. After the completion of the experimental period, the lung tissues were collected in liquid nitrogen and cryostat sections of 10 ìm thickness were incubated for the demonstration of phosphatases and dehyrogenases. The positive and negative controls were carried out wherever possible. The lungs showed moderate AKPase, ATPase and G-6-Pase activity whereas the SDH and LDH activity varied from weak to moderate in alveolar septae.ACPase activity was increased in histiocytes of alveolar septae. The alveolar ducts showed negligible activity of all the enzymes studied. The results may be correlated with cellular damage and lysis of macrophages of the alveoli.

Clinico-therapeutic studies were made on thirty clinical cases of lantana toxicity in cattle. The affected animals showed anorexia, constipation, icteric mucous membranes, lachrymation, oligurea,cracks on muzzle, dehydration and rumen stasis. Biochemical analysis revealed that 61.53 % of early presented cases and 100 % of late presented cases were having biphasic Vanden Bergh reaction. Hypoglycemia and increased total protein level were present in late presented cases. Markedly elevated values of total bilirubin, BUN, AST and alkaline phosphatase in both the early and late cases of lantana toxicity indicated hepatic and renal dysfunction.