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Comparison of flunixin meglumine and flurbiprofen for control of ocular irritative response in dogs
1991
Millichamp, N.J. | Dziezyc, J.
Dogs were treated with the cyclo-oxygenase inhibitors flunixin meglumine IV or flurbiprofen topically. Acute inflammation was induced in the eyes by disruption of the anterior lens capsule, using a neodymium:yttrium aluminum garnet laser. Pupil diameter and intraocular pressure were measured before and after inducing ocular inflammation. Both drugs maintained mydriasis and increased intraocular pressure in the inflamed eyes, compared with untreated controls.
Show more [+] Less [-]Effect of flurbiprofen on facility of aqueous outflow in the eyes of dogs
1991
Millichamp, N.J. | Dziezyc, J. | Olsen, J.W.
Aqueous outflow from cannulated canine eyes was determined, using a constant-pressure perfusion technique. The effect of topically applied flurbiprofen, a cyclo-oxygenase inhibitor, on outflow in eyes with or without neodymium:yttrium aluminum garnet laser-induced inflammation was measured. Flurbiprofen caused decrease in aqueous outflow that was more marked in the inflamed eyes.
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