Refine search
Results 1-9 of 9
Immunomodulative effects of bovine immunodeficiency-like virus (BIV)-infection and mixed infection of BIV and bovine leukemia virus on sheep
1996
Hirai, N. (Hokkaido Univ., Sapporo (Japan)) | Kabeya, H. | Ohashi, K. | Sugimoto, C. | Onuma, M.
Role of adherent mononuclear cells derived from adult pigs and suckling piglets in response to pokeweed mitogen-induced immunoglobulin production
1986
Hagiwara, S. (Hokkaido Univ., Sapporo (Japan). Faculty of Veterinary Medicine) | Maeda, Y. | Ohsugi, T. | Namioka, S.
Lymphocyte transformation of peripheral blood lymphocytes and plaque forming cells of the spleen and the mesenteric lymph node in suckling piglets with and without immunopotentiators
1983
Namioka, S. | Ohsugi, T. | Fujimoto, T. | Maeda, Y. (Hokkaido Univ., Sapporo (Japan). Faculty of Veterinary Medicine)
Detection of the meq gene in the T cell subsets from chickens infected with Marek's disease virus serotype 1
2005
Chang, K.S.(Hokkaido Univ., Sapporo (Japan)) | Ohashi, K. | Lee, S.I. | Takagi, M. | Onuma, M.
The meq gene was thought to be only detected in Marek's disease virus serotype 1 (MDV1) including a very virulent strain, Md5, while L-meq, in which a 180-bp sequence is inserted into the meq open reading frame, is found in other strains of MDV1, such as CVI988/R6. However, both meq and L-meq were previously detected by PCR in chickens infected with MDV1, suggesting hat MDV1 may consists of at least two subpopulations, one with meq, the other with L-meq. To further analyze these subpopulations, we analyzed the time course changes in distribution of these subpopulations among T cell subsets from chickens infected with MDV1. Both meq and L-meq were detected in CD4(+) and CD8(+) T cells infected with strain Md5 or CVI988/R6. The shift in MDV subpopulations from one displaying meq to the other displaying L-meq and/or the conversion from meq to L-meq occurred mainly in the CD8(+) T cell subset from Md5- infected chickens. PCR products corresponding to L-meq rather than meq were frequently amplified from the CD8(+) T cell subset from CVI988/R6-infected chickens. These results suggest that a dominant subpopulation of MDV1 changes depending on the T cell subsets, and that L-meq is dominantly present in the CD8(+) T cells which play a role in the clearance of pathogenic agents.
Show more [+] Less [-]Characterization of two monoclonal antibodies which recognize different subpopulations of chicken T lymphocytes
1990
Kondo, T. (Hokkaido Univ., Sapporo (Japan). Faculty of Veterinary Medicine) | Hattori, M. | Kodama, H. | Onuma, M. | Mikami, T.
Nonspecific cell-mediated cytotoxicity of peripheral blood lymphocytes derived from suckling piglets
1987
Onizuka, N. (Hokkaido Univ., Sapporo (Japan). Faculty of Veterinary Medicine) | Maede, Y. | Ohsugi, T. | Namioka, S.
Cytokines: Communication molecules that influence the process of disease
1997
Splitter, G. (Department of Animal Health and Biomedical Sciences, Wisconsin (USA))
Immune response to Echinococcus multilocularis infection in the mouse model: A review
1992
Playford, M.C. (Hokkaido Univ., Sapporo (Japan). Faculty of Veterinary Medicine) | Kamiya, M.
Characterization of transplantable subline MDCC-MSB1-Clo. 18 derived from MXCC-MSB1 [chickens]
1984
Higashihara, T. | Kunihiro, K. | Yamaki, T. | Kodama, H. | Izawa, H. | Mikami, T. (Hokkaido Univ., Sapporo (Japan). Faculty of Veterinary Medicine) | Okada, I.
