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Linkage of a microsatellite marker to the canine copper toxicosis locus in Bedlington terriers.
1997
Yuzbasiyan Gurkan V. | Blanton S.H. | Cao Y. | Ferguson P. | Li J. | Venta P.J. | Brewer G.J.
Молочная продуктивность коров белорусской черно-пестрой породы с различными генотипами по гену каппа-казеина
2008
Yatsyna, O.A. | Smuneva, V.K., Vitebsk State Academy of Veterinary Medicine (Belarus) | Epishko, T.I., National Academy of Sciences. Scientific and Practical Center of Animal Breeding (Belarus)
In the research the genetic structure of populations of bulls Vitebsk of cattle breeding state farm and cows of Belarusian Black-and-White breed of Joint-Stock Company Olgovskij of Vitebsk region (Republic of Belarus) on a locus of a gene of kappa-casein was analyzed. As a result of genotyping a gene of kappa-casein by DNA-diagnostics method there were revealed three genotypes CSN3**AA, CSN3**AB, CSN3**BB. Frequency of occurrence of homozygous genotype CSN3**AA at cows has made 69,5%, at bulls of Vitebsk cattle breeding state farm - 78,3%; heterozygotic genotype CSN3**AB - 26,3% and 20,5%; homozygous genotype CSN3**BB - 4,2% and 1,2%, respectively. Frequency of CSN3**A allele in population of cows and bulls has made 0,83 and 0,88; CSN3**B - 0,17 and 0,11%, respectively. The presence of authentic influence of polymorphic variants of a gene of kappa-casein on level of milk yield and fat and protein content in cow milk was stated. The highest milk productivity in course of 305 days of lactation was observed at cows with homozygous genotype CSN3**BB (5984 kg), that was on 890 kg higher than in animals with genotype CSN3**AB (5094 kg), and on 1406 kg higher (Р less than 0,05), than at animals with CSN3**AA genotype (4578 kg). Cows with B kappa-casein allele in genome were characterized by higher fat content in milk (CSN3**AB - 3,61%, CSN3**BB - 3,72%) than animals with a CSN3**AA genotype - 3,60%. Cows with genotype CSN3**BB had higher level of protein in milk (3,28%) in comparison with the animals with CSN3**AA genotype (3,18%). In animals with CSN3**AB genotype the mentioned above index 3,19%. Research results showed that genetic variants of the gene of kappa-casein are important for selection practice as they could be used as breeding-genetic markers which could raise milk yields and protein content in milk
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