Definition of quality parameters and chemical composition of feeds, evaluation their nutritional value and composing on this basis optimal rations for high productive animals are the most significant conditions for their health and production. More often metabolism disorders registers in the conditions of intensive animal production, at high dairy efficiency and intensive fattening. At animals at disorder of key parameters of technology (unbalanced feeding, hypodynamia, lack of insolation) is broken metabolism, decreases natural resistance, goes down quality of production that conducts to disease, premature culling and to the compelled slaughter of animals. On frequency these diseases occupy on the average 10% from all noncontagious diseases, and on dairy complexes with industrial technology and in specialized feeding economy at intensive cultivation on their share it is necessary over 30% of a noncontagious pathology. Today the control of rations on such indicators, as dry matter level, quantity of exchange energy, the maintenance of a crude and digested protein, amino acids, sugars, starch, cellulose, fat, macro-and microelements, vitamins, and also sugar-energy-protein and calcium-phosphoric parities, acid-base balance has got special value. The lack of those or other nutrients causes infringement of a clinical condition of animals and reduces their efficiency. Among the most widespread diseases of the animals registered in animal industry: cattle ketosis, osteodystrophy, endemic struma, hypomagnesiemia tetany, pasturable tetany, microelementosis, hypovitaminoses A and Е.

The use of low intensive red spectrum laser radiation for prevention of abomasoenteritis in calves is effective method. As a result the increase of erythrocytes level and saturation of them with hemoglobin happens. Natural resistance with bactericide and lysozyme activity are going up phagocytosis of neutrophils is activated. The most successful method are magnet-laser radiation of blood and laser acupuncture. There was studied the low intensive red spectrum laser radiation for prevention of abomasoenteritis in calves. During the research it is established, that preventive efficiency at abomasoenteritis in the first trial group has made 80%, in the second and the third - 90%. As a result of the spent work high preventive efficiency of action of the low intensive red spectrum laser radiation is established at prescription of through-skin blood irradiations by the therapeutic laser in a combination to a constant magnetic field and as a result influences on biologically active points. Application of these ways allows to reduce level of disease of animal abomasoenteritis. As a result of physiotherapeutic influence there is content increase of erythrocytes in blood of calves and saturation their haemoglobin. Natural resistance with bactericide and lysozyme activity are going up phagocytosis of neutrophils is activated. The most successful method are magnet-laser radiation of blood and laser acupuncture. It is caused by that positive changes occurring in an organism, have been more brightly expressed and besides preventive and economic efficiency of these ways of irradiation also were at higher level. In the tabular form dynamics of morphological indicators at calves under the influence of laser radiation, dynamics of indicators of natural resistance at calves as a result of the laser therapy, some biochemical indicators of blood is presented at carrying out of research.

The purpose of the research was establishment of hepatic diseases spread in cattle fattening. Trials were conducted with total number of hybrids IV-V generation of black-motley heifer with pedigree Hereford bulls. It has been established the wide spread (22,4%) of hepatic pathology. The leading place among all hepatic pathologies belongs to fatty hepatosis (13,4%) with weakly expressed symptoms, decrease of serum protein level, albumin, glucose and increase of bilirubin, globulins, hepatic enzymes and strong pathology-anatomical and histological manifestations. In the tabular form results of histologic research of liver, some biochemical indicators of blood of healthy and sick animals (M +/- m), the clinical symptoms revealed during the various periods are resulted | Целью исследований являлось изучение структуры и установление широты распространения болезней печени у крупного рогатого скота на откорме. Опыты проведены на широком поголовье помесей IV-V поколения тёлок чёрно-пёстрой породы с племенными быками герефордской породы. Установлено широкое (22,4%) распространение гепатопатий. Ведущее место среди различных форм поражения печени принадлежит жировому гепатозу - 13,4%, морфофункцинальный профиль которого определяется слабо выраженными клиническими симптомами, уменьшением уровня общего белка, альбуминов, глюкозы, повышением концентрации билирубина, активности гепатоспецифических ферментов, а также всех фракций глобулинов, яркой и характерной патологоанатомической и гистологической картиной. В табличной форме приведены результаты гистологического исследования печени, некоторые биохимические показатели крови здоровых и больных животных (M +/- m), клинические симптомы, выявленные в различные периоды

There was studied the ulcerous changes in a rennet stomach paries. The analysis of literary data has allowed to choose a way of reproduction of rennet stomach ulcer at calves by means of haemodynamic frustration of rennet stomach site. During experiment has been reproduced ulcer abomasit at 13 heifers. In the course of work the young growth of black-motley breed at the age of 1-2 months has been involved. Before operation to calves neuromuscular relaxant Rometar intramuscularly was entered. Then alcoholic narcosis on M.V.Plakhotin intravenously was entered. Belly cavity on a white line of stomach, receding from chondroxiphoid cartilage on 4-5 cm, was opened. A cut in length 10-12 cm was done. Through the formed aperture rennet stomach was taken, then on the big curvature gastroepiploic artery was found, into which by medical syringe through an insulinic needle was entered warmed up to 38 deg C the 8-% solution of sulfosalicylic acid in a dose of 5 ml. Changes from a serous cover of rennet stomach observed at once after introduction of acid solution. At first on an artery course rough spastic reductions of rennet stomach muscles have been noticed. After that, in the same place, there was anaemia of serous cover, then, stagnant hyperaemia. For the control of results in 3-5 weeks made the compelled slaughter of calves with the diagnostic purpose and found out rennet stomach ulcers of various size. Result of the given work is that the given method gives the chance to reproduce haemodynamic rennet stomach ulcer at calves of any age by means of 8% solution of sulfosalicylic acid. Thus, the experimental model of rennet stomach ulcer at the calves, caused by introduction of 8% solution of sulfosalicylic acid, is in the main similar to spontaneous disease. | Целью экспериментальной работы явилось изучение ульцерозных изменений в стенке сычуга. Анализ литературных данных позволил выбрать способ воспроизведения язвы сычуга у телят посредством гемодинамических расстройств участка сычуга. Во время эксперимента был воспроизведен язвенный абомазит у 13 телочек. В процессе работы был задействован молодняк крупного рогатого скота черно-пестрой породы в возрасте 1-2 месяцев. Перед операцией телятам вводили внутримышечно миорелаксант Рометар. Затем вводили внутривенно алкогольный наркоз по M.B. Плахотину. Брюшную полость вскрывали по белой линии живота, отступая от мечевидного хряща на 4-5 см. Делали разрез длиной 10-12 см. Через образовавшееся отверстие извлекали сычуг, затем находили на большой кривизне желудочно-сальниковую артерию, в которую шприцом через инсулиновую иглу вводили подогретый до 38 deg С 8-процентный раствор сульфосалициловой кислоты в дозе 5 мл. Изменения со стороны серозной оболочки сычуга наблюдали сразу же после введения раствора кислоты. Сначала по ходу артерии были замечены бурные спастические сокращения мышц сычуга. После этого, там же, возникала анемия серозной оболочки, затем, застойная гиперемия. Для контроля результатов через 3-5 недель производили вынужденный убой телят с диагностической целью и обнаруживали язвы сычуга различной величины. Результатом данной работы является то, что данный метод дает возможность воспроизводить гемодинамическую язву сычуга у телят любого возраста при помощи 8-процентного раствора сульфосалициловой кислоты. Таким образом, экспериментальная модель язвы сычуга у телят, вызванная введением 8-процентного раствора сульфосалициловой кислоты, в основных чертах сходна со спонтанным заболеванием.

Sodium hypochlorite solution is an effective means in control of noncontagious aetiology diseases, accompanied by development of endogen intoxications. The detoxification action of sodium hypochlorite is that in the body there is no becomes free active oxygen, oxidizing there toxic and ballast substances as bilirubin, urea, ammonia, uric acid, creatinine, cholesterol, carbonic oxide, acetone, acetone acetate, ethanol, methanol, barbiturates, etc. The detoxification action of sodium hypochlorite is shown in neutralization of exotoxins and endotoxins of pathogenic microorganisms as it represents a compound of the small molecular mass and the small structural size. In this connection it freely gets through membranes of cells and oxidizes the toxins containing not only in blood, but also in cells. From this follows, that sodium hypochlorite models not only oxidizing function of cytochrome Р-450 of liver, but also phagocytal function of neutrophilic leucocyte. It leads to inactivation of large toxic molecular compounds both on a surface of uniform elements, and in blood plasma while effective methods reduce intoxication at the expense of removal of the average molecules circulating in plasma

There was studied the therapeutic efficiency of sorbent Lactofiltrum in a complex therapy of abomasoenteritis at calves. It represents the complex preparation containing 75% of hydrolytic lignins and 25% of lactulose. Action of lignins is based on ability to sorb and strongly to keep toxins of exogenous and endogenous origins, the pathogenic microorganisms which are present in enteral mediuim. Lactulose, a part of prebiotics Lactofiltrum, is a synthetic disaccharide. It is not exposed to splitting by enzymes in thin intestines. The active substance lactulose starts to operate in a thick gut where under the influence of intestinal microflora it is transformedto low-molecular organic acids, basically dairy, acetic, oil and propionic. Thanks to acidification of intestinal contents growth of putrefactive and pathogenic microflora chokes, osmotic pressure in a gleam of a thick gut increases. Lactofiltrum possesses high therapeutic efficiency. The experiment has shown 100% effectiveness in treatment. Economic effect is 1,63 rubles in control group and 3,52 rubles in experimental group from 1 ruble of expenditure. This treatment is economically profitable. In the tabular form the content of the general bilirubin, cholesterol, triglycerides and glucose in blood serum, urea and creatinine, daily average body weight gain and epizooty, morphological indicators of blood, dynamics of the general protein and albumens at calves with abomasoenteritis are presented. Lactofiltrum has a high therapeutic effect. Pharmacology action is associated with intestinal digestion normalization due to absorption of toxins and useful bacteria stimulation. The experiment has shown 100% effectiveness in treatment. This treatment is economically profitable.