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Preoperative administration effect of metronidazole, ceftriaxone sodium and their combination on stenotic index of jejunal anastomotic segment of dogs
2014
Rehan, Rafique., Veterinary Research Institute, Lahore, Pakistan | Asi, Muhammad Nadeem., Department of Clinical Medicine & Surgery, University of Agriculture Faisalabad, Faisalabad, Pakistan | Saqib, Muhammad., Department of Clinical Medicine & Surgery, University of Agriculture Faisalabad, Faisalabad, Pakistan | Hussain, Muhammad Hammad., Department of Clinical Medicine & Surgery, University of Agriculture Faisalabad, Faisalabad, Pakistan | Sial, Awais-ur-Rehman., Department of Clinical Medicine & Surgery, University of Agriculture Faisalabad, Faisalabad, Pakistan | Mushtaq, Aqsa, Veterinary Research Institute, Lahore, Pakistan
The jejunum is the longest part of the small intestine and its lumen is mainly involved in the absorption of the nutrients. The present study was conducted to evaluate the effects of metronidazole, ceftriaxoine sodium and their combination on the stenotic index of the end to end jujunal anastomotic site. To accomplish this, 20 healthy stray dogs were subjected to end to end jejunal ansastmosis. Dogs in Group A (control) underwent jejunal anstomosis with no antibiotic prophylaxis, while those in Group B received surgery and metronidazole alone at 50 mg/kg, those in Group C received ceftriaxone sodium intravenously at 30 mg/kg body weight prior to surgery and dogs in Group D were given metronidazole in combination with ceftriaxone sodium at 50 mg/kg and 30 mg/kg, respectively, 2 h before surgical intervention. No significant difference (p 0.05) in the stenotic index was observed at 14 days after jejunal anastomosis. These findings indicate that prophylactic administration of metronidazole and ceftriaxone sodium alone or in combination had no significant effect on the stenotic index of the jejunum.
Show more [+] Less [-]Preliminary efficacy trial of cymelarsan in mice artificially infected with Trypanosoma brucei brucei isolated from a dog in Zambia
1995
Syakalima, M. (Hokkaido Univ., Sapporo (Japan)) | Yasuda, J. | Hashimoto, A.
An efficacy trial of Cymelarsan (R) on a Zambian strain of Trypanosoma brucei brucei was done. Twenty-five male mice were infected intraperitoneally with 10(6) of T. b. brucei isolated from a dog. Five groups of 5 mice were treated with 0 (control), 0.25, 0.5, 1.0 and 2.0 mg/kg cymelarsan, respectively. The target was to achieve aparasitaemia for 30 days post-treatment, euthanising those that remained parasitaemic or relapsed before then. The 0.25 and 0.5 mg/kg groups remained parasitaemic although the parasitaemic levels were reduced. The 1.0 mg/kg group had a proportion of aparasitaemic mice. However, all mice in the 2.0 mg/kg group remained aparasitaemic until day 20 when 2 mice relapsed. These results suggested that more than 2.0 mg/kg was required to eliminate this strain
Show more [+] Less [-]Effect of diminazene block treatment on live redwater vaccine reactions
2004
Combrink, M.P. | Troskie, P.C. (Agricultural Research Council, Onderstepoort (South Africa). Onderstepoort Veterinary Inst.)
Evaluation of isometamidium levels in the serum of sheep and goats after prophylactic treatment against trypanosomosis
2004
Wesongah, J.O. | Murilla, G.A. | Kibugu, J.K. (Kenya Trypanosomiasis Research Inst., Kikuyu (Kenya)) | Jones, T.W.
A bioequivalence and pharmacokinetic evaluation of two commercial diminazene aceturate formulations administered intramuscularly in cattle
1994
Gummow, B. | Swan, G.E. (Pretoria Univ., Onderstepoort (South Africa). Faculty of Veterinary Science) | Du Preez, J.L.
Role of obioactin on toxoplasmacidal activity within mouse peritoneal macrophages
1994
Yang, M.P. (Chungbuk National University, Cheongju (Korea Republic). College of Veterinary Medicine)
Protective efficacy of isometamidium chloride and diminazene aceturate against natural Trypanosoma brucei, Trypanosoma congolense and Trypanosoma vivax infections in cattle under a suppressed tsetse population in Uganda
2004
Magona, J.W. | Mayende, J.S.P. | Okiria, R. | Okuna, N.M. (Livestock Health Research Inst., Tororo (Uganda))
Resistance to trypanocidal drugs - suggestions from field survey on drug use in Kwale district, Kenya
2003
Mugunieri, G.L. | Murilla, G.A. (Kenya Trypanosomiasis Research Inst., Kikuyu (Kenya))
Evaluation of a short-term in vitro growth-inhibition test to determine susceptibility of Trypanosoma vivax stocks to various trypanocides
1994
Zweygarth, E. (Agricultural Research Council, Onderstepoort (South Africa). Onderstepoort Veterinary Inst. (South Africa)) | Kaminsky, R. | Moloo, S.K.
The susceptibility of Trypanosoma congolense isolated in Zambezia Province, Mozambique, to isometamidium chloride, diminazene aceturate and homidium chloride
2005
Jamal, S. | Sigauque, I. | Macuamule, C. (National Directorate of Livestock, Maputo (Mozambique)) | Neves, L. | Penzhorn, B.L. | Marcotty, T. | Van den Bossche, P.
