The present study reports the concentration of Copper, Zinc, Iron and Manganese in the blood plasma of male kutchi camels during their breeding season. The respective concentrations of the plasma trace minerals were 112.94 ±O.44, 105.65±2.08, 117.65±1.72 and 160.29±0.75 µ/dl.

This study was designed in order to clarify the effect of ethanol drinking on the mineral contents on liver, kidney, muscle and hair. Forty-five rats were divided into 2 groups and a control group. The control group received tap water and the other 2 groups were given 8 % and 40 % ethanol as drinking source. Liver, kindney, muscle and hair samples were taken and analyzed for zinc, calcium and copper contents by atomic absorption spectrophotometric methods. The zinc content of muscle showed significant (P0.01) decrease in both groups. The calcium content of hair showed significant (P0.1) increase in 8 % ethanol group. The copper contents of kidney and muscle in 8 % ethanol group and liver in 40 % ethanol group showed significant (P0.1) decrease

In the conditions of the Republic of Belarus there was studied the preventive efficiency of various forms of a complex additive Felutsen against polymicroelementoses of calf-bearing dry cows and its influence on some of biochemical blood indexes. Research results proved high prophylactic efficacy of various forms of the additive Felutsen against polyhypomicroelementoses of calf-bearing dry cows. Restoration of a microelement homeostasis of cows made it possible to normalize the functional activity of liver, to prevent development renal insufficiency and dystrophic changes in bone tissue. The most expressed metabolic changes in blood of calf-bearing dry cows were stated after application of the carbohydrate-mineral additive Felutsen-briquette universal. There was given the analysis of structure of studied forms of complex additive Felutsen; indexes of trace element metabolism in cows; indexes of protein metabolism and level of nonprotein nitrogen; indexes of blood characterizing the functional condition of liver and carbohydrate metabolism of cows; indexes of trace element metabolism in cows after the termination of application of the additive.

Investigation of spreading of diseases of micronutrient deficiencies at cow breeding farms of Grodno district of the Republic of Belarus depending on the season and character of polymicroelementoses, as well as the determination of relations between polyhypomicroelementoses and state of new born calves were realized. Clinical investigation of 1350 milked and calf-bearing dry cows and biochemical analysis of 450 blood samples taken at nongrazing time (before cows pasture) and at pasture time were conducted. The following animal groups were selected: the first group – cows after calving; the second group – the cows of three month pregnancy; the third group – calf-bearing dry cows. The following groups were selected among calf-bearing dry cows in nongrazing and pasture time: clinically healthy cows, which had biochemical blood changes, showing development of subclinical polyhypomicroelementoses (n = 20); clinically healthy cows with blood indicators, standing in limits of physiological standards. Number of calves was considered after calving of cows of both groups. Body weight, realization of staying and sucking position, evidence of sucking reflex, and calves disposition to neonatal pathology were considered in the study. Research result showed that cow microelementoses were marked by the development of subclinical polyhypomicroelementoses. Among cow polyhypomicroelementoses there was noted the domination of states followed by lowering of zinc, cobalt and cuprum content. Polyhypomicroelementoses were developing both in winter housing season and in course of grazing season. Polyhypomicroelementoses involve cows of different physiological states and were spreading more intensively at cow dry period and after calving. Calves obtained from cows with polyhypomicroelementoses often had the state of hypotrophy and high incidence of dyspepsia at colostric period. Clinical and biochemical status of the analyzed calves was characterized by signs of intoxication and hepatic insufficiency

In the conditions of the Republic of Belarus it was determined that application of monocalcium phosphate in a dose of 10 gram per 1 kilogram of mixed fodder and specified doses of trace elements (cuprum; zink; cobalt; manganese; iodine) in diets of growing pedigree bull calves made it possible to increase indices of body weight of young cattle stock of the third experimental group in comparison with animals of the first and the second groups on 18,3 and 11 kg or respectively on 3,9 and 2,3%; as well as to increase the intensity of their growth. The highest daily average live weight gain was noted at animals of the third experimental group – 1062 grams. It was higher than at bull calves of the first and the second groups respectively on 31,3 and 12,8 grams, or on 3 and 1,2%. Application of monocalcium phosphate in a dose of 10 gram per 1 kilogram of mixed fodder favorably affected the formation of desirable type of sexual behavior and indices of semen production quality. Thus, in the third experimental group in comparison with animals of the first and the second groups the volume of ejaculate was on 0,2 and 0,1 ml higher (or on 5,8 and 2,9%); quantity of sperm in ejaculate - on 0,7 and 0,3 billion, or on 35 and 15%.

Investigation of acute and subchronic (chronic) toxicity of complexinates of trace elements in experiments with calves was realized in the conditions of the Republic of Belarus. The realized experiments were based on developed in Belarus veterinary preparations for the treatment and prevention of diseases connected with disorders of trace elements exchange containing chelate compounds of trace elements with sodium ethylene diamine acetate: Cuprovet (on the basis of CuNa); Cobalvet (on the basis of CoNa), Zinkovet (on the basis of ZnNa), and Feravet (on the basis of FeNa). There were the following indexes of ferrum in nephros - 55,3 +/- 2,26, in muscles - 134 +/- 26,6 mkg/g, and in liver - 565 +/- 35,5 mkg/g after administration of Feravet. There were the following index of zinc in nephros - 56,3 +/- 2,64, in muscles -25, 8 +/- 1,23 and in liver - 84,4 +/- 3,29 mkg/g after administration of Zinkovet. There were the following indexes of cuprum in nephros - 4,1 +/- 0,325, in muscles - 2,33 +/- 0,117, and in liver - 12,3 +/- 1,12 mkg/g after administration of Cuprovet. There were the following indexes of cobalt in nephros - 40,35 +/- 2,29, in muscles - 12,5 +/- 0,98, and in liver - 126,5 +/- 10,45 ng/g after administration of Cobalvet. Parameters of toxicity of all preparations were by the example of laboratory mice, rats and calves given. Content of trace elements in blood of calves in dynamics of the experiment was analyzed. There were determined parameters of acute toxicity of the analyzed preparations: they all could be referred to substance hazard category 4 (low-hazardous substances). The determined parameters of acute toxicity made it possible to recommend them for treatment and prophylaxis of microelementoses of cattle, as well as to use them as feed additives taking into consideration that defect action levels of the analysed preparations exceed the deficiency needs of cattle in case of their limited cumulation

Research on working out of a new fodder additive on the basis of rape (Brassica napus) phospholipids which included mineral substances necessary for normal functioning of cattle was realized in the conditions of the Republic of Belarus. Results of biochemical analysis of 35240 blood samples revealed that 15-40% of studied animals had abnormalties in vitamin, protein and mineral metabolism and lowering of immunobiological disease resistance. There was correlation dependence between the degree of metabolic orders and the state of forage reserve of a forage reserve. The lowering of forage reserve caused the increasing of metabolic disorders. As a whole forages of the surveyed farms were low in content of copper, zinc, cobalt and selenium and could not provide physiological requirements of animals without introduction into rations of specialized additives