Refine search
Results 1-4 of 4
Comparison of humoral immunity and induction of proliferating T lymphocytes in vaccinia virus-infected rabbits and rhesus macaques.
1994
Schaffner J.W. | Dittmer U. | Otteken A. | Coulibaly C. | Bodemer W. | Voss G. | Hunsmann G.
Vaccina virus (VV) infection induces specific antibodies and cytotoxic T cells in various animal species. Therefore, helper T cells also should be induced that stimulate the humoral and cellular immune responses. We determined such helper T-cell activity in 2 species after VV infection. Rabbits and rhesus macaques were infected with the Copenhagen strain of VV or with recombinant VV expressing retroviral proteins. Animals of both species developed antibodies and specific proliferative T-cell response. This reactivity could be enhanced by booster infection with VV. The proliferating macaque cells were CD4+ and major histocompatability complex class II-restricted. These data confirm the broad immunogenicity of VV. Expression of additional polypeptides expressed from a recombinant VV does not lead to altered immune response to VV antigens. However, strength of the helper T-cell response, as well as clinical reactions, differed between macaques and rabbits. Infection with recombinant VV as delivery vectors offers the opportunity for combined vaccination against recombinant proteins and does not diminish cellular and humoral immune responses to VV itself.
Show more [+] Less [-]Perfect state of Microsporum gypseum complex isolated from animals and soils.
1988
Lee H.J. | Choi W.P.
Mating experiments were performed to elucidate the distribution of perfect state of Microsporum gypseum complex originating from animals and soils in Korea. A total of 30 strains of M. gypseum complex, composed of 16 from animals and 14 from soils, mated with the tester strains of Nannizzia incurvata, N. gypsea and N. fulva. Among 30 strains of M. gypseum complex examined, 16 strains (53.3%) were N. incurvata, 13 strains (43.3%) N. gypsea and 1 strain (3.3%) N. fulva. Among 13 strains of dog isolates, 8 strains (61.5%) were N. incurvata and 5 strains (38.5%) N. gypsea. And each strain isolated from Korean native goat, monkey and albino rat was N. gypsea. Among 14 strains of soil isolates, 8 strains (57.2%) were N. incurvata, 5 strains (35.7%) N. gypsea and 1 strain (7.2%) N. fulva. And - mating type was more frequently obseved than + mating type in the strains of N. incurvata and N. gypsea. By this study, N. fulva was isolated the first time in Korea.
Show more [+] Less [-]Helminth parasites of the Japanese monkey, Macaca fuscata fuscata in Ehime prefecture, Japan
1988
Itoh, K. (Hokkaido Univ., Sapporo (Japan). Faculty of Veterinary Medicine) | Oku, Y. | Okamoto, M. | Ohbayashi, M. | Kitamura, Y. | Shibahara, T.
Prevalence of virulent Rhodococcus equi in isolates from soil collected from two horse farms in South Africa and restriction fragment length polymorphisms of virulence plasmids in the isolates from infected foals, a dog and a monkey
2001
Takai, S. (Kitasato Univ., Towada (Japan). Animal Hygiene Dept.) | Henton, M.M. | Picard, J.A. | Guthrie, A.J. | Fukushi, H. | Sugimoto, C.
