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Induction of squamous cell carcinomas and adenocarcinomas in mouse lung by intratracheal instillation of benzo(a)pyrene and urethan
1986
Kim, S.H. (Korea Advanced Energy Research Inst., Seoul (Korea R.)) | Lee, C.S. (Kyongbuk National Univ., Taegu (Korea R.). Dept. of Veterinary Medicine)
The present study was carried out to observe the histopathological changes in the lung of A/J, C57BL/6N, DBA/2 and NIH-GP mice intratracheally instillated with benzo(a)pyrene or urethan. In the group of intratracheal instillation with benzo(a)pyrene and charoal powder, squamous cell carcinomas and adenocarcinomas were induced. Tumors were induced in high incidence in the lung of A/J and C57BL/6N mice. Especially, squamous cell carcinomas were induced in high incidence and were well-differentiated in the lung of A/J mice
Show more [+] Less [-]Immunobiological studies on mice treated with chemical carcinogen, 3-methylcholanthrene, 2; rosette formation and natural killing (NK) activity of splenic lymphocytes
1986
Song, H.J. | Kim, S.H. | Kim, J.M. (Chonbuk National Univ., Chonju (Korea R.))
The present study was undertaken to evaluate rosette formation and NK activity of splenic lymphocytes in 3-methylcholanthrene (MCA) treated mice. Mice were sensitized iv with 0.1ml of 1% sheep red blood cell (SRBC) suspension were treated with a single ip injection of olive oil alone or with different doses of MCA in oil at various time before or after sensitization, and were challenged at 4 days after SRBC. Rosette formation and NK activity of splenic lymphocytes were measured at 24 hrs after challenge
Show more [+] Less [-]Immunobiological studies in mice treated with chemical carcinogen, 3-methylcholanthrene, 1; footpad swelling reaction and antibody titer in serum
1986
Song, H.J. | Kim, J.M. (Chonbuk National Univ., Chonju (Korea R.). Dept. of Veterinary Medicine)
Studies on mycoplasma infection of laboratory mice and antibiotic susceptibility against isolates
1986
Chung, Y.Y. (Korea Air and Correspondence Univ., Seoul (Korea R.). Dept. of Agri.) | Cho, S.Y. | Lee, H.C. (Yongnam Univ., Taegu (Korea R.). Dept. of Animal Science)
Isolation and identification of mycoplasma were performed to clarify mycoplasma infection of mice fed by convectional feeding at two (K1, K2) institutes in Korea. The twenty mice to be tested were randomly samples from each of 10 breeding colonies in respective institute. Identification of the mycoplasma strains isolated from the nasal cavity, lung and synovia of mice was made according to the morphology of colonies, biological and biochemical properties with special reference to M. pulmonis, M. arthritidis and M. neurolyticum
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