The calf was a congenital abnormal stillbirth of Sahiwal breed of zebu cattle, with multiple musculoskeletal defects. It was born to a heifer in its first calving. The calving was normal; however, calf born had multiple anomalies. The body of the calf was flashy just like a rubber balloon filled with water (case of hydropsy). The body was without hairs (hypotrichosis). Skeleton was noncalcified and ribs were cartilaginous. The body was identifiable in three regions: head, thoraxabdomen, and limbs. Morphologically limbs were developed but were quite short in length with well-developed hoof. There was one eye like structure just above the mouth (case of cyclopia). The tongue was developed and was protruded from mouth. There was one additional structure on the head, looked like outgrowth of muscles covered with thin skin, had openings of nostrils on the end. In autopsy abdominal body cavity was found filled with fluid. The visceral organ seemed normal. It was identified as female; however, ovaries and genital tract could not be traced and examined. It was the first calving of its dam with the complete gestation period of 287 days like a normal period in cattle. Pieces of tissue from lung and blood from the heart and vena cava were collected; however, cultures were found heavily contaminated with bacterial growth. The actual cause of the defects could not be established, might be defects of certain genes responsible for incomplete growth and development.

The buffalo calves became ataxic at 6.16±1.07 minute of acepromazine administration. There was good sedation. The animals stood up with ataxia at 131.5±17.80 minute and complete recovery took 211.83±6.94 minutes. Significant hypotension and tachycardia were observed after acepromazine administration. Midazolam caused ataxia at 3.33±0.76 minute and animals went into sternal recumbency at 34.0±15.85 minute. There was good muscle relaxation. Complete recovery took 183.5±10.92 minutes. Significant increase in respiratory rate was observed at the its peak effect. A significant reduction in mean arterial pressure (MAP) was also seen at 30 minute of midazolam administration. Diazepam produced ataxia within one minute and animals went into sternal recumbency. It produced quick onset of action and delayed recovery. A significant hypotension was observed at 5 minute of diazepam with decreased pulse pressure. No change was observed in electrocardiograph on administration of acepromazine and diazepam but slight increase in the amplitude of primary T-wave was observed after midazolam administration.

In the conditions of the Republic of Belarus there were studied circadian rhythms of some haemotological and biochemical blood indexes of clinically healthy calves and calves with a respiratory syndrome. There was analyzed the efficiency of administration a new complex mineral preparation CMP for correction of internal desynchronoses in complex therapy of calves with respiratory pathologies. Diseases of calves with a respiratory syndrome were accompanied by infringements of circadian fluctuations rhythm (internal desynchronosis) of haemotological and biochemical blood indexes. Application of an antimicrobial preparation Ampicillin for treatment of respiratory diseases of calves promoted the recovery of calves. Introduction of CМP preparation into therapeutic regimen of calves with respiratory syndrome proved to be rather effective; it promoted the correction of metabolic desynchronoses which accompanied the basic disease. Combined application of CМP and Ampicillin made it possible to speed up the clinical recovery of calves and on 30% to prevent animal mortality.

On the basis of the spent research high enough preventive efficiency of Ehrakond application, low intensive laser radiation together with a constant magnetic field is defined that allows to recommend them for wide application in the program of immunocorrection of an organism of agricultural animals. At the first stage of the research in immune deficiency when in blood of newborn calves almost there are no antibodies, influence on biologically active points of an udder of cows (intensity 10 mW/square cm, expositions of seconds) has made positive impact on increase of immune properties of colostric milk. Use of immunostimulants Ehrakond also has increased immunocompetent properties of cow milk (7,5 mg on 1 kg of body weight once a day within 15 days). At feeding of colostrum the physiological condition, growth and development of calves have considerably improved. In the second (when colostric protection factors in an organism decline, and own organism forms them insufficiently) and the third (decrease in immune reactance at changes in feeding and the maintenance of calves) immune deficiency, application of immunostimulants Ehrakond and influence of low intensive laser radiation together with a constant magnetic field on reflexogenic zones on a young growth organism has made positive impact indices of natural resistance of calves. It has led to activization of factors of natural nonspecific protection of an organism that has considerably improved a physiological condition and has increased natural immunity of an organism to diseases. However, the best results on natural resistance, efficiency and safeties of calves have been reached at an irradiation at the BAP initial stage of a mammary gland at cows by low intensive laser radiation together with a constant magnetic field, with the subsequent bottle-feeding of the irradiated colostrum to newborn calves; in 10 days of a life to calves the preparation Ehrakond was entered. | На основании проведенных исследований определена достаточно высокая профилактическая эффективность применения Эраконда, низкоинтенсивного лазерного излучения совместно с постоянным магнитным полем, что позволяет рекомендовать их для широкого применения в программе иммунокоррекции организма сельскохозяйственных животных. На первом этапе исследований в период иммунного дефицита, когда в крови новорожденных телят почти отсутствуют иммуноглобулины, воздействие на биологически активные точки вымени коров (интенсивность 10 мВт/см2, экспозиции секунд) оказало положительное влияние на повышение иммунных свойств колострального молока. Использование иммуностимулятора Эраконд также повысило иммунокомпетентные свойства молока коров (7,5 мг на 1 кг живой массы один раз в сутки в течение 15 дней). При скармливании колострального молозива значительно улучшились физиологическое состояние, рост и развитие телят. В период второго (когда колостральные факторы защиты в организме угасают, а собственный организм образует их недостаточно) и третьего (снижение иммунной реактивности при изменениях в кормлении, содержании телят) иммунного дефицита, применение иммуностимулятора Эраконд и воздействие низкоинтенсивного лазерного излучения совместно с постоянным магнитным полем на рефлексогенные зоны на теле молодняка оказало положительное влияние показатели естественной резистентности телят. Это привело к активизации факторов естественной неспецифической защиты организма, что значительно улучшило физиологическое состояние и повысило естественную невосприимчивость организма к болезням. Однако, наилучшие результаты по естественной резистентности, продуктивности и, сохранности телят были достигнуты при облучении на начальном этапе БАТ молочной железы у коров низкоинтенсивным лазерным излучением совместно с постоянным магнитным полем, с последующим выпаиванием облученного молозива новорожденным телятам; через 10 дней жизни телятам вводили препарат Эраконд.

In the conditions of the Republic of Belarus there was determined the therapeutic efficacy of combined application of a complex antibacterial veterinary drug (containing lincomycin and spectinomycin) and Trivitim for the treatment of calves with respiratory diseases. In course of the study of 12 1-1,5 month old calves with respiratory diseases there were analyzed the hematological blood indexes, white blood cell differential and content of total protein in blood serum before the beginning of treatment and on the seventh and fourteenth days after beginning treatment. Research results showed that application the antibacterial veterinary drug in complex therapy with Trivitim in treatment of calves proved to be efficient. Their administration shortened the terms of recovery and prevented animal death as well as promoted the normalization of hematological and biochemical blood indexes.

In the conditions of the Republic of Belarus there were determined the doses of application of siliceous sapropel as well as there were studied the indexes of ruminal digestion and digestibility of diet nutrient substances by bull calves. The studied siliceous sapropel of the lake Pribylovichi (Belarus) occurence on 42% consisted of organic substances and on 58% - of mineral substances: calcium, phosphorus, magnesium, potassium, sodium, iron, zinc, manganese, and copper. The studied sample of sapropel did not render toxic action on test objects of infusorian Tetrahymena pyriformis in the conditions of its addition into the basic forage in number of 1%; 3%; 5%; and 10%. However, its higher concentrations (10%) retarded the development of Protozoa. Feed additives with the content of siliceous sapropel in mixed fodder in dose of 1%, 3% and 5% increased the relative biological value of forage in the experiments on test objects of infusorians Tetrahymena pyriformis in the average respectively on 5,4%, 5,0 and 2,6%. Higher concentrations of sapropel in mixed fodder (5 and 10%) lowered its nutritional value. Inclusion of siliceous sapropel in bull calve rations activated the enzymatic processes in farding bag and increased the digestibility nutritive elements on 2,3-3,6% except for protein, digestibility which was practically at identical level at animals of all groups.

In the conditions of the Republic of Belarus there was analyzed the productivity of 13-18-month old young stock of cattle which was bred for meat with various levels of energy value nutrition. Also, there were noted their slaughter qualities and chemical composition of meat. Administration of diet rations with an increased level of exchange energy and the best indices of protein fissility rendered a positive influence on productivity of young stock of fattening cattle and made it possible to obtain 1103-1100 gram of body weight gain. As a result, the energy value gain was 22,9-22,6 MJ along with conversion of metabolizable energy at a gain - 24,7-25,3%. Consumption of metabolizable energy per 1 MJ along with body weight gain were within 4,7-5,0 MJ. Feeding of rations with various levels of the studied factor rendered the positive influence on slaughter qualities, made it possible obtain slaughter yield of 53,6-54,6% at an optimum ratio of nutrients in meat. Feeding of bull calves with diets with excessive content (up to 10%) of metabolizable energy made it possible to lower the prime cost of obtained breeding products on 0,55%.

In the conditions of the Republic of Belarus there was analyzed the efficiency of application of a whole milk substitute Biomilk-11 and feed additive SFDK-1 (biologically active enzymatic feed additive) for breeding of young stock of cattle, by an example of calves of black-and-white breed. In course of the study there was analyzed the composition of the feed additive SFDK-1 (weight fraction of dry matter; weight fraction of protein; content of amine nitrogen; cellulose fiber activity) as well as the physical and chemical indexes of the whole milk substitute Biomilk-11 (moistness; crude protein; crude fat; crude fibre). There were presented indexes of live weight gain of experimental and control calves as well as the dynamics of average daily weight gains in experimental group. Research results proved the efficiency of application of both additive for calves feeding.

In the conditions of the Republic of Belarus there were analyzed high productive traits of meaty calves and cross breeds bred in accordance with a system cow-calf, as well as the possibilities of using veal meat obtained in ecologically safe areas for infant food production. At the age of 6,5-7 months the weight of fresh carcass of bull-calves of sharolez breed in comparison with aberdin-angus х black-motley herdmates was on 41,6 kg (Р less than 0,001) higher, carcass yield and slaughter yield – on 13,8% (Р less than 0,001) and 13,6% (Р less than 0,001), respectively. The fat content in sharolez meat was 4,9% against 8,9%; protein - 21,9% against 18,8%. The black-motley suckling bull-calves surpassed their herdmates which were grown up by technology of dairy cattle breeding at the age of 6-6,5 months according to indexes of weight of fresh carcass - on 16,3 kg or 21,7% (Р less than 0,01); according to indexes in a slaughter yield - on 16,6% (Р less than 0,001); and according to indexes meat flesh in a carcass - on 1,5%. According to quality indexes, amino acid structure, acceptable concentration of toxic elements content, pesticides, antibiotics, radionuclides and other harmful substances the veal meat of calves which were bred on a system a cow-calve in ecologically pure zones proved to be important meat raw materials to produce infant food products.

In the conditions of the Republic of Belarus there was studied the clinical and biochemical status of pregnant cows, as well as the determination of the main reasons of disease incidence of new-born calves with dyspepsia (dyspeptic disorder). Realized clinical and biochemical studies showed that the inappropriate feeding of pregnant cows in animal breeding farms in housing season of husbandry caused the disorders of metabolic processes in the experimental animals. In blood there was noted the lowering of indexes of alkalinity reserve, glucose, phosphorous, carotine, disturbance of calcareous and phosphorous ratio. In other words, in pregnant cows there were stated the latent forms of osteodystrophia, hypovitaminosis A, hypoglycemia, and acidosis. All these factors caused the irritation and damage of liver and other organs. Mammary gland of diseased animals released colostrum milk of low quality and according to the content of nutritious and protective elements quantity it was of low quantity. Besides, derangements in calf feeding of pregnant nonmilking cows led to birth of calves with low resistance indexes to the influence of external environment factors.