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Flurbiprofen toxicity in 2 dogs
2013
Lee, Y., Seoul National University, Seoul, Republic of Korea | Nam, E.H., Seoul National University, Seoul, Republic of Korea | Park, S.H., Seoul National University, Seoul, Republic of Korea | Song, C.Y., Seoul National University, Seoul, Republic of Korea | Lee, Y.U., Seoul National University, Seoul, Republic of Korea | Lee, J.M., Seoul National University, Seoul, Republic of Korea | Park, J.H., Seoul National University, Seoul, Republic of Korea | Hwang, C.Y., Seoul National University, Seoul, Republic of Korea
Two dogs were presented with melena, vomiting and depression after accidental swallowing of candy form of Strepsils (flurbiprofen), which is one of non-steroidal anti-inflammatory drugs used in human medicine for controlling a sore throat. These dogs had common signs of anemia induced by gastrointestinal ulceration and hemorrhage with azotemia and leukocytosis. The dogs were treated with blood transfusion, fluid therapy, proton-pump inhibitor, antiemetics, mucus protectant and antibiotic. Although most of clinical signs of two dogs were resolved, azotemic problem with evidence of renal injury have remained.
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