fenbendazole safety tested in pigs, significant gross or histopathologic lesions not found

Dirofilaria immitis adults, dogs (exper.), description of pulmonary embolism caused by treatment with thiacetarsamide, scanning electron and light microscopy; first report of 'complicated' arteriosclerotic plaques in conjunction with D. immitis infection

Dirofilaria immitis adults, dogs (exper.), effect of therapy with prednisolone vs. aspirin on pulmonary thromboembolism caused by thiacetarsamide treatment, scanning electron and light microscopy

small and large strongyles, ponies, cambendazole, effects of periodic therapeutic dosing (1974-1978) on strongyle egg counts and on mares' reproductive performance with teratologic implications, critical test, comparison of benzimidazole-resistant species of small strongyles in 4 populations

Two of 3 groups of Holstein-Friesian steers (groups II and III; n = 5 each) were fed a ration containing corn naturally contaminated with 800 ng of aflatoxin/g. The other group of steers (group I; n = 5) was fed a ration containing noncontaminated corn. The respective rations were fed for 17.5 weeks, except the ration given to group III; the latter's first diet (contaminated with aflatoxin) was changed to a noncontaminated diet after 15 weeks, continuing for the remaining 2.5 weeks. All steers were killed and tissues and fluids were obtained for aflatoxin analysis. Although aflatoxin B1 and M1 could be detected in blood and urine at several sampling times during the experimental period in groups II and III steers (given the diets containing aflatoxin), there appeared to be no effects on body weight gains and immune phenomena, such as lymphoblastogenesis and antibody production, but there was a waning of the delayed cutaneous hypersensitivity in steers given aflatoxin-contaminated diets. In group III animals (diet was changed to noncontaminated ration at 15 weeks), aflatoxin B1 and M1 disappeared from urine before they were slaughtered. All tissues and fluids, except the rumen contents from these group III steers, were void of detectable aflatoxins B1 and M1 at necropsy. The concentrations of aflatoxin B1 in the rumen content of the latter steers were low. All tissues collected at necropsy from the group II steers fed the aflatoxin diet throughout the 17.5 weeks had detectable aflatoxins B1 or M1 present.