In the conditions of the Republic of Belarus there was determined the therapeutic efficacy of combined application of a complex antibacterial veterinary drug (containing lincomycin and spectinomycin) and Trivitim for the treatment of calves with respiratory diseases. In course of the study of 12 1-1,5 month old calves with respiratory diseases there were analyzed the hematological blood indexes, white blood cell differential and content of total protein in blood serum before the beginning of treatment and on the seventh and fourteenth days after beginning treatment. Research results showed that application the antibacterial veterinary drug in complex therapy with Trivitim in treatment of calves proved to be efficient. Their administration shortened the terms of recovery and prevented animal death as well as promoted the normalization of hematological and biochemical blood indexes.

In the conditions of the Republic of Belarus there was studied the influence of methods and means of spot heating and localization of warmth on indexes of microclimate in piglet breeding houses and resting area of piglets and their growth parameters. In course of the study there taken into consideration the indexes of an average temperature on piglet resting area housings; atmosphere relative humidity, air velocity, content of carbon dioxide, content of hydrogen nitride in the housing and resting areas of piglets. Research results of microclimate of swine breeding areas and resting areas of piglets under different means and methods of heating and warmth localization showed that the it was the most efficient to add for the local heating in the first three weeks of suckling period the glow-discharge tubes or in suckling period or weanling periods - the heated floors; and in suckling period - brooders in the form of tops with shields.

In the conditions of the Republic of Belarus there was realized a scientific and economic experiment on studying the influence of a multi-enzyme feed additive on productivity, viability, growth and development of calves. The multi-enzyme additive contained in its formula xilanaza; glucanase; cellulose; and dolomite (as a filling agent). It was determined that young growth of cattle which were fed with the multi-enzyme additive in dose 1 gram per 6 kilogram of milk by the end of the experiment had a live weight gain on 13,6% higher than in a control group. Calves which were fed with the additive were characterized by more stretched constitution, had well developed thorax and good development of skeleton in comparison with analogues from the control group.

In the conditions of the Republic of Belarus there was studied the efficiency of application of granulated and extruded lupine (Lupinus) in feeding of bull claves. It was determined that after lupine extruding the quantity of sugar in it increased on 45% due to lowering of starch content. The inclusion of extruded lupine into bull calves diets made it possible to increase the digestibility of dry and organic substances, protein and nitrogen-free extractive substances. The highest average daily weight gain (842 gram) was stated at claves which were fed with mixed fodder with 15% of extruded lupine; this was on 7,5% than in a control group. In the conditions of feeding with the granulated lupine the average daily weight gain increased on 5,3% in comparison with crushed one. In course of study there was analyzed the dependence chemical composition of lupine on the processing method; blood composition of the studied animals; diets of experimental animals; digestibility of nutrient substances of forages; balance and intake of nitrogen; biochemical blood composition; changes of live weight and average daily weight gain.

In the conditions of the Republic of Belarus there was studied the possibility of increasing of meat yield productivity of ducklings of Temp cross in the conditions application of parental lines of Peking ducks of German breeding Stolle Seddin Vital (SVV) cross. In course of the study there was realized a comparative evaluation of linear and crossbred ducklings in accordance with meat qualities and blood indexes. There were presented the results of morphological composition of liner and crossbred duck carcasses; dynamics of changes of lipid exchange (total lipids; cholesterine; triglyceride) of ducklings; morphological composition of carcasses of father and mother combinations; blood indexes of ducklings; blood indexes of crossbred ducklings of final combinations. Research results showed that crossbred ducklings had high meat properties which exceeded the purebred ones. In ducklings with lower indexes of fattiness of carcasses there was noted the lowering of concentration of total lipids, cholesterine and triglyceride in blood.

In the conditions of the Republic of Belarus there was analyzed the efficiency of application of a whole milk substitute Biomilk-11 and feed additive SFDK-1 (biologically active enzymatic feed additive) for breeding of young stock of cattle, by an example of calves of black-and-white breed. In course of the study there was analyzed the composition of the feed additive SFDK-1 (weight fraction of dry matter; weight fraction of protein; content of amine nitrogen; cellulose fiber activity) as well as the physical and chemical indexes of the whole milk substitute Biomilk-11 (moistness; crude protein; crude fat; crude fibre). There were presented indexes of live weight gain of experimental and control calves as well as the dynamics of average daily weight gains in experimental group. Research results proved the efficiency of application of both additive for calves feeding.

In the conditions of the Republic of Belarus there was studied the formation of nonspecific protection factors of the first year foals. By a principle of conditional analogues there was generated a group of clinically healthy foals at which monthly from bulbar veins there were taken tests of blood for hematological and biochemical analysis. From the obtained data it was visible, that within the first year of foal life there were taking place the processes of formation of nonspecific protection factors of an organism which were accompanied by a gradual increasing of quantity of erythrocytes, haemoglobin, leukocytes, certain change in the diagramme, and also increasing of bactericidal and lysozyme activity of blood serum. However, at seven-month age there was marked a considerable decrease in number of erythrocytes, leukocytes, concentration of haemoglobin, bactericidal and lysozyme activity of blood serum is marked, in leukogram share reduction of segmented neutrophils, and at the same time, the content of eosinocytes and lymphocytes increased. It testified the decreasing of protective forces of an organism during this period. Consequently, the seventh month in the postnatal period of foal life proved to be the most critical.

Investigation of method of gastroenteritis treatment of stores by means of application of enterosorbents was realized in the conditions of the Republic of Belarus. For the experiment there was used preparation Lactofiltrum containing 80% of hydrolyzed lignin and 20% of lactulose applied in dose of 0,3 g/kg once a day during 7 days. Efficiency of application of Lactofiltrum was compared with enterosorbent SV-2, which contained alcaline hydrolyzed lignin applied in dose of 1 g/kg once a day during 7 days. Four experimental groups piglets sick with gastroenteritis in the age of 1,5-2 months, with body weight of 15-17 kg were used in the experiment. The first group piglets were entered 0,3 g/kg body mass of Lactofiltrum once a day during 7 days. The second group piglets were entered enterosorbent SV-2 in dose of 1 g/kg in course of 7 days. For the piglets of the third group there was applied the complex of analysed preparations in same course of treatment. The fourth group of piglets was entered enrotim 10% in dose of 1 ml/ 20 kg of body mass. All animals had the same conditions of feeding and keeping. Research results showed that application of Lactofiltrum, SV-2 and their complex provided high antioxidative, detoxification, gepathoprotective activities. These preparations proved to be effective means of pathogenetic therapy for the treatment of gastroenteritis of piglets, both as individual preparations, and complex application. Comparative estimation of treatment methods of gastroenteritis showed that these preparations (except enrotim 10%) made it possible to regulate the metabolic processes due to elimination of intoxication, positive influence on hematopoiesis. The preparations lowered the duration of clinic manifestation of a disease and facilitated its duration, had gepathoprotective and antioxidative activity

Determination of degree and relations between derangements of metabolic processes in calves with respiratory syndrome in the milking period was realized in the conditions of the Republic of Belarus. Research results showed that the calves with the respiratory syndrome had expressed metabolic processes disturbances, which were marked in the analyzed biochemical blood indexes (total protein; albumins; urea; creatinine; glucose; cholesterin; triglycerids; bilirubin; ALP; AAT; SGPT; calcium; phosphorous; magnesium; iron; manganese; cobalt; cuprum; zinc). In calves with respiratory syndrome there was noted the increased content of crude protein in blood serum (71,42 +/- 2,57 g/l P less than 0,05), low urea level (3,08 +/- mmol/l). There was the increased level of creatine (574,11 +/- 65,26 mkmol/l; P less than 0,01) and bilirubin (8,11 +/- 1,15 mkmol/l; P less than 0,05). Glucose concentration in blood of diseased calves was at below standard level (3,49 +/- 0,69 mmol/l). Glucose indexes varied and were changing during a day; and depended on muscular activity, intervals between feeding and hormonal regulation. Diseased calves had high cholesterol level in blood serum (4,07 +/- 0,34 mmol/l; P less than 0,05), which was stated in case of liver disease and hypothyroidism. Phosphor level was higher than the standard indexes of healthy calves (2,85 +/- 0,03 and 2,05 +/- 0,05, respectively). Content of magnesium, cobalt and zinc in blood of the diseased calves was lower than in healthy ones. Calves with respiratory pathology had protein, fat, hydro-carbonic and mineral metabolic processes

Investigation of acute and subchronic (chronic) toxicity of complexinates of trace elements in experiments with calves was realized in the conditions of the Republic of Belarus. The realized experiments were based on developed in Belarus veterinary preparations for the treatment and prevention of diseases connected with disorders of trace elements exchange containing chelate compounds of trace elements with sodium ethylene diamine acetate: Cuprovet (on the basis of CuNa); Cobalvet (on the basis of CoNa), Zinkovet (on the basis of ZnNa), and Feravet (on the basis of FeNa). There were the following indexes of ferrum in nephros - 55,3 +/- 2,26, in muscles - 134 +/- 26,6 mkg/g, and in liver - 565 +/- 35,5 mkg/g after administration of Feravet. There were the following index of zinc in nephros - 56,3 +/- 2,64, in muscles -25, 8 +/- 1,23 and in liver - 84,4 +/- 3,29 mkg/g after administration of Zinkovet. There were the following indexes of cuprum in nephros - 4,1 +/- 0,325, in muscles - 2,33 +/- 0,117, and in liver - 12,3 +/- 1,12 mkg/g after administration of Cuprovet. There were the following indexes of cobalt in nephros - 40,35 +/- 2,29, in muscles - 12,5 +/- 0,98, and in liver - 126,5 +/- 10,45 ng/g after administration of Cobalvet. Parameters of toxicity of all preparations were by the example of laboratory mice, rats and calves given. Content of trace elements in blood of calves in dynamics of the experiment was analyzed. There were determined parameters of acute toxicity of the analyzed preparations: they all could be referred to substance hazard category 4 (low-hazardous substances). The determined parameters of acute toxicity made it possible to recommend them for treatment and prophylaxis of microelementoses of cattle, as well as to use them as feed additives taking into consideration that defect action levels of the analysed preparations exceed the deficiency needs of cattle in case of their limited cumulation