Feeding replacement calves of 369-460,8 kg of live weight with diets of non-degradable protein level that is 10% higher than approved norm increases metabolically energy transformation into weight gain energy from 19,10 to 20,81 MJ or at 9% that promotes increase of average daily weight gains at 5% and decrease of energy spends at 5% counted per 1 unit of energy for weight gain. Ejaculate volume is increased at 14% and sperm concentration – at 12%

It is determined on the basis of conducted researches on perfection of energy-protein nutrition norm of young cattle of 6-12 months of age that 11,5 MJ of exchange energy at 6-7 months of age and decease to 10 MJ for 12 month of age is needed in 1 kg of dry matter to get 1000 g of average daily weight gain. 8-9 g of digestible, 5 g of non-digestible protein should come for 1 MJ of exchange energy of a diet. 1 kg of DM (Dry Matter) should contain 133-150 g of crude and 46-54 g of non-digestible protein

In the conditions of the Republic of Belarus there was determined the influence of lactulose of the clinical state of weanling piglets, as well as analysis of its preventive and therapeutic efficacy. For the experimental group of piglets in course of 5 days before weaning the lactulose for administrated daily in combination with feed in course of 5 days in dose of 0,002 gram per kilogram of live weight. In 3-5 days after weaning the diarrhea was stated in 4,1% of experimental piglets. The clinically evident efficiency of application of the synthetic disaccharide was showed in lowering of disbacteriosis level in weaning piglets on 33,7%. Besides, there was analyzed the therapeutic efficacy of lactulose for weaning piglets diseased with gastroenteritis. They were administrated lactulose in dose of 0,03 grams per kilogram of live weight once a day after feeding in course of 7 days. Haematologic and biochemical blood indexes of experimental and control groups of piglets were analyzed. Research results showed that application of lactulose promoted the creation of optimal conditions for beneficial microflora, stimulated its reproduction, suppressed the development of opportunistic pathogens.

In the conditions of the Republic of Belarus there was studied the influence of methods and means of spot heating and localization of warmth on growth, viability and physiological status of piglets. In course of realization of the experiment there was issued a task of scientific substantiation of application of brooders of different construction and proposition of the most optimal method of microclimate formation in resting area of piglets for the increasing of their growth and viability, and improvement of physiological state. Research results showed that the highest indexes of growth and viability, and intensity of metabolic processes in piglets were obtained after the combined application in course of the first three weeks of suckling period of filament lamps and heated floors and brooders in the form of tops with shields, and at a later stage – only brooders of this construction in comparison with animals which were in course of a suckling period under the infrared radiation lamps or at the space-heating floor.

In the conditions of the Republic of Belarus there was studied the clinical and biochemical status of pregnant cows, as well as the determination of the main reasons of disease incidence of new-born calves with dyspepsia (dyspeptic disorder). Realized clinical and biochemical studies showed that the inappropriate feeding of pregnant cows in animal breeding farms in housing season of husbandry caused the disorders of metabolic processes in the experimental animals. In blood there was noted the lowering of indexes of alkalinity reserve, glucose, phosphorous, carotine, disturbance of calcareous and phosphorous ratio. In other words, in pregnant cows there were stated the latent forms of osteodystrophia, hypovitaminosis A, hypoglycemia, and acidosis. All these factors caused the irritation and damage of liver and other organs. Mammary gland of diseased animals released colostrum milk of low quality and according to the content of nutritious and protective elements quantity it was of low quantity. Besides, derangements in calf feeding of pregnant nonmilking cows led to birth of calves with low resistance indexes to the influence of external environment factors.

In the conditions of the Republic of Belarus there were analyzed the efficiency of application of a new mineral additive produced of the basis of carnallite brine (the national local raw material) as a part of mixed fodders for feeding of young stock of cattle. There was analyzed its influence on digestibility of a diet nutrients in cattle rations and on animal productivity. Inclusion of carnallite brine in mixed fodders structure for fattening young cattle rendered a positive influence on forage palatability. Forage consumption on a per head basis increased on 5,4%. Optimum dose of addition of carnallite brine in mixed fodder - 0,85%. Feeding of young cattle with the experimental mixed fodders did not render negative influence on hematological indices and physiological condition of animals. Use in young cattle rations of the mixed fodder containing 0,85% of carnallite brine promoted the increasing of nutrient digestibility on 3,4-5,7%. In the conditions of feeding of mixed fodders with other doses of carnallite did not cause any changes in digestibility of nutrients. Feeding of the prepared mixed fodder with 0,85% of carnallite brine to young growth of cattle made it possible to increase the growth energy on 5%.

In the conditions of the Republic of Belarus there was realized an ecological monitoring of sources of water supply in the conditions of a swine breeding complex and adjoining settlements. There was studied the influence of a large swine breeding complex on water quality of closed type water sources. There was marked a microbial contamination of water depending on remoteness of animal breeding object and season of a year. There were determined the seasonal changes of physical properties, chemical and bacteriological composition of water used for swine breeding. There were noted changes in water quality in the process of its flow from the point of water inlet up to the place of its consumption. Results of influence of improved water on piglets were presented. There was studied the possibility of improvement of water quality by means of its treatment with solution of potassium hypermanganate (0,01%) which made it possible to increase average daily live weight gain of piglets. In course of the study there was realized the analysis of protein spectrum of blood serum of piglets; dynamics of body weight and average daily weight gain of experimental piglets.

In the conditions of the Republic of Belarus there was analyzed the efficiency of application of a probiotic lactic casein feed additive DKM which was developed in the Institute of Microbiology of the National Academy of Sciences of Belarus. The analyzed additive contained specially selected lactic-acid bacteria with a high bioartificial potential of metabolites. In course of the experiment there was studied the consumption of fodders (milk; oats; mixed fodders) by experimental calves; dynamics of live weight gain in the beginning and at the end of the experiment; average daily weight gain. Also, there were analyzed the background indexes of blood serum of calves, as well as the indexes of blood serum of calves in a month after application of DKM additive. Research results showed that application of the feed additive DKM promoted better palatability and use of fodders and rendered positive influence on animal productivity. Also, there was marked the normalization of metabolism that was proved y the laboratory tests of blood serum.

Investigation of connection of experimental trichophytosis and relations between changes of clinical implications of disease and dimensions of some immunological indexes was realized in the conditions of the Republic of Belarus. At the first stage of the experiment there analyzed 48 guinea pigs (Cavia porcellus) infected with Trichopyton verrucosum. Phagocytic ability of phagocytes and level of circulating antibodies in indirect hemagglutination test were investigated each 5 days before and during disease. The second stage was realized by the example of 2,5-6 months old calves. In course of study there were analyzed blood and blood serum indexes, indexes of nonspecific resistance, as well as some indexes of cell-mediated immune response and antibody mediated immunity. Comparative analysis the following morphological and biochemical blood indexes of clinically healthy calves, calves after trichophytosis, and calves sick with mild, moderate and severe of disease were presented: erythrocytes; hemoglobin; leukocytes; basophils; eosinophiles; rods; microxyphils; lymphocytes; monocytes; ESR; total albumin; albumins; alpha globulins; beta globulins; gamma globulins; carotene; calcium; inorganic phosphorous; alkaline reserve; copper. The realized experiment made it possible to conclude that determination intensity of leukocyte absorption of microconidia of the agent, antibodies against the agent, and specific for cytoplasm fungus, morphological and biochemical blood indexes made it possible to control the development of inflammatory phenomenon in centers of infection, as well as to predict the formation of face, infiltrative and suppurant disease forms

Analysis of efficiency of prebiotics and probiotics and different systems of their application for the focused formation of bacteriocenosis of gastro-intestinal tract of calves was realized in the conditions of the Republic of Belarus. There were used 7 groups of calves: 1 – clinically healthy; 2 – calves with diarrheal syndrome which did not get preparations; 3 – calves were administrated daily with liquid probiotic Bifidoflorin Zhidkij in dose 20 ml in course of 20 days; 4 – calves were administrated daily with prebiotic Biofon with colostral milk or milk in dose 20ml in course of 20 days; 5 – calves were administrated daily with prebiotic Biofon-AIL in dose 20 ml in course 20 days; 6 – calves were administrated with probiotic Bifidoflorin Zhidkij simultaneously with prebiotic Biofon; 7 – calves were administrated with probiotic Bifidoflorin Zhidkij in combination with prebiotic Biofon-AIL. In course of studies there was analyzed the age-specific dynamics of bifidus bacteria, lactic acid bacillus, and Escherichia quantities in calves excrements. Research results showed that application of the proposed prebiotics and probiotics promoted the earlier and active contamination of intestines with obligate anaerobe gram-positive flora with its dominative position in relation to gram-negative nonsporeforming facultative anaerobic flora. At the stage of the second aging immunodeficiency the analyzed preparations rendered the resolving effect. The highest positive indexes were obtained after combined application of probiotic Bifidoflorin Zhidkij with prebiotic Biofon-AIL