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Indices for nutritional condition and thresholds for winter survival in sika deer in Hokkaido, Japan
2000
Yokoyama, M. (Hokkaido Univ., Sapporo (Japan)) | Uno, H. | Suzuki, M. | Kaji, K. | Ohtaishi, N.
An analysis of the growth based on the size and age distributions of the hawksbill sea turtle inhabiting Cuban waters
2000
Kobayashi, M. (Hokkaido Univ., Sapporo (Japan))
Postnatal changes in Rho and Rho-related proteins in the mouse brain
2000
Komagome, R. (Hokkaido Univ., Sapporo (Japan)) | Kimura, K. | Saito, M.
To provide information on the role of Rho, a GTP-binding protein, in postnatal development of the brain cells, the change in the levels of Rho protein and Rho-related proteins was examined in the brain of mice for two weeks after birth, in parallel with the changes in the activity of marker enzymes for neuronal and glial cells. The activities of acetylcholine esterase and choline acetyltransferase of whole brain homogenate, both of which are neuronal marker enzymes, were progressively increased in an age-dependent manner. The activity of 2',3'-cyclic nucleotide 3'-phosphohydrolase, a glial marker enzyme, increased markedly between one and two weeks after birth. In contrast, the levels of RhoA and RhoB in the membrane fraction were decreased during the postnatal period. The amount of Rho GDP dissociation inhibitor, a regulatory protein for Rho, was unchanged, while those of Rho target proteins, Rock-2 and citron, were gradually increased. Since the inactivation of Rho is known to induce neurite extension and neuronal and glial differentiation in vitro, our results suggest that the Rho signalling pathway plays a regulatory role in the postnatal differentiation of neuronal and glial cells in vivo
Show more [+] Less [-]Parasitic forms of a myxosporean in the kidney of the arctic lamprey, Lampetra japonica: An ultrastructural study
2000
Mori, K. (Hokkaido Univ., Sapporo (Japan)) | Takahashi Iwanaga, H. | Iwanaga, T.
Experimental reproduction of itai-itai disease, a chronic cadmium poisoning of humans, in rats and monkeys
2000
Umemura, T. (Hokkaido Univ., Sapporo (Japan))
Models for regional heartwater epidemiology in a variable environment
2000
Levins, R. (Harvard School of Public Health, Boston, MA (USA). Dept. of Population and International Health)
The distribution of tsetse (Diptera: Glossinidae) and bovine trypanosomosis in the Matutuine district, Maputo Province, Mozambique
2000
Sigauque, I. | Van den Bossche, P. | Moiana, M. | Jamal, S. | Neves, L.
The prevalence of internal and external parasites in pigs of different ages and sexes in Southeast district, Botswana
2000
Nsoso, S.J. | Mosala, K.P. | Ndebele, R.T. | Ramabu, S.S.
The role of parasitic diseases as causes of mortality in cattle in a high potential area of central Kenya: a quantitative analysis
2000
Kanyari, P.W.N. | Kagira, J. (Nairobi Univ. (Kenya). Dept. of Pathology, Microbiology and Parasitology)
Diurnal activity patterns of Glossina brevipalpis and G. austeni (Diptera: Glossinidae) in South Africa, with reference to season and meteorological factors
2000
Kappmeier, K. (Agricultural Research Council, Onderstepoort (South Africa). Onderstepoort Veterinary Inst.)