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Antioxidant status, and blood zinc and copper concentrations in dogs with uncomplicated babesiosis due to Babesia canis infections
2021
Teodorowski Oliwier | Winiarczyk Stanisław | Tarhan Duygu | Dokuzeylül Banu | Ercan Alev Meltem | Or Mehmet Erman | Staniec Marta | Adaszek Łukasz
The aim of the study was to demonstrate a link between uncomplicated Babesia canis infection in dogs and blood concentrations of zinc and copper and erythrocytic antioxidant defence – activities of glutathione (GSH), superoxide dismutase (SOD) and catalase (CAT).
Show more [+] Less [-]The preventive role of Spirulina platensis (Arthrospira platensis) in immune and oxidative insults in a stress-induced rat model
2021
Seyidoğlu Nilay | Köşeli Eda | Gurbanlı Rovshan | Aydın Cenk
There is a balance between oxidative stress, antioxidant capacity and immune response. Their roles in physiological and behavioural mechanisms are important for the maintenance of the organism’s internal equilibrium. This study aimed to evaluate the antioxidant effects of the exogenous alga Spirulina platensis (Arthrospira platensis) in a stress-induced rat model, and to describe its possible mechanism of action.
Show more [+] Less [-]Effects of vitamin C and magnesium L-threonate treatment on learning and memory in lead-poisoned mice
2021
Bislimi Kemajl | Mazreku Ilir | Halili Jeton | Aliko Valbona | Sinani Kushtrim | Hoxha Liridon
The aim of this study was to investigate the effects of vitamin C (vit C) and magnesium L-threonate (MgT) on the learning ability and memory of mice intoxicated with lead acetate.
Show more [+] Less [-]Assessment of the usefulness of image reconstruction in the oblique and double-oblique sagittal planes for magnetic resonance imaging of the canine cranial cruciate ligament
2021
Przeworski Adam | Adamiak Zbigniew | Nowicki Michał | Mieszkowska Marta | Tobolska Angelika | Głodek Joanna
The aim of the study was to determine the quality and significance of the magnetic resonance image of the canine knee after reconstruction in the oblique and double-oblique sagittal plane. This reconstruction and 3D images are rarely used in common protocols due to the longer study time they require. The study aimed to demonstrate significance for such diagnostic images in specific sequences in order to stimulate consideration of their more frequent use in diagnosis of diseases of the cruciate ligament in dogs.
Show more [+] Less [-]Comparative expression analysis of inflammatory and immune-related genes in cattle during acute infection with foot-and-mouth disease virus in Egypt
2021
El Nahas Abeer F. | Abd El Naby Walaa S.H. | Khatab Shymaa A. | Fergany Al-Zahraa A. | Rashed Rashed R.
Foot-and-mouth disease is a highly infectious viral disease affecting all cloven-footed domestic animals. The three foot-and-mouth disease virus (FMDV) serotypes A, O and SAT2 are at present the greatest threat to susceptible animals in Egypt. The aim of the present study was, for the host factors associated with different FMDV infections in cattle during the acute phase, to compare these factors’ influence on the expression of the IL-10, TLR-2, TNF-α, CXCL10, CD48, NFATC4 and IFNG inflammatory and immune-related genes.
Show more [+] Less [-]Protective effects of bisoprolol against cadmium-induced myocardial toxicity through inhibition of oxidative stress and NF-κΒ signalling in rats
2021
Liu Jinhua | Xie Ying | Han Zhujun | Wang Hailong | Xu Wenhu
The aim of the study was to investigate the mitigative effects of bisoprolol (BIS) in cadmium-induced myocardial toxicity on oxidative stress and its inhibitive effect on nuclear factor kappa-light-chain-enhancer of activated B cells (NF-kB) signalling in rats.
Show more [+] Less [-]Effects of topical treatment of foot rot in sheep using ozonated olive ointment
2021
Szponder Tomasz | Zdziennicka Joanna | Nowakiewicz Aneta | Świeca Michał | Sobczyńska-Rak Aleksandra | Żylińska Beata | Patkowski Krzysztof | Junkuszew Andrzej | Wessely-Szponder Joanna
Foot rot in small ruminants is highly contagious, causes severe lameness, and impairs fertility and wool and meat production. It is usually treated with parenteral antibiotics, with attendant antibiotic resistance risk, and with bactericidal footbaths, potentially harmful to humans and the environment. An alternative treatment in sheep is proposed based on repeated topical ozonated ointment application. Its effectiveness and safety were evaluated by estimation of acute-phase response, biochemical indicators of organic damage, and antioxidant/oxidant balance (AOB).
Show more [+] Less [-]Evaluation of serum and urine neutrophil gelatinase-associated lipocalin and cystatin C as biomarkers of acute kidney injury in horses
2021
Siwińska Natalia | Żak Agnieszka | Pasławska Urszula
Diagnosis of acute kidney injury (AKI) in horses is difficult at the subclinical stage, due to nonspecific clinical signs. The aim of this study was to evaluate the concentrations of selected serum and urinary biomarkers in healthy horses, horses at risk of AKI, and those with clinical AKI.
Show more [+] Less [-]Regional distribution of non-human H7N9 avian influenza virus detections in China and construction of a predictive model
2021
Huang Zeying | Li Haijun | Huang Beixun
H7N9 avian influenza has broken out in Chinese poultry 10 times since 2013 and impacted the industry severely. Although the epidemic is currently under control, there is still a latent threat.
Show more [+] Less [-]Semi-stable production of bovine IL-4 and GM-CSF in the mammalian episomal expression system
2021
Blanco Federico Carlos | Vazquez Cristina Lourdes | García Julia Sabio y | Rocha Rosana Valeria | Gravisaco María José | Forrellad Marina Andrea | Magistrelli Giovanni | Bigi Fabiana
Granulocyte-macrophage colony stimulating factor (GM-CSF) and interleukin-4 (IL-4) are cytokines widely used in ex vivo monocyte differentiation experiments, vaccine formulations and disease treatment. The aim of this study was to produce recombinant bovine GM-CSF and IL-4 in an episomal expression system that conserves the postransductional modification of the native proteins and to use the products to differentiate bovine monocytes into dendritic cells.
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