Attempts were made to determine the clinical features and the causative organism of ringworm occurring in a cat in Chinju city, Korea. Alopecia and greyish white crusty lesions were obseved around the eye, nose and posterior limb while irregular, partial loss of hairs and white scales were in the ear, neck and abdomen lesions. Direct microscopic and cultural examination were carried out for the hairs and crusts taken from the skin lesions, and the causative organism was identified as M. canis

To examine the selectivity of diltiazem, used in the cardiovascular diseases, on alpha-1 and alpha-2 adrenoceptor-induced pressor responses, effect of diltiazem on alpha-adrenoceptor agonist-induced pressor responses were investigated in urethane-anesthetized rabbits and spinal rabbits. Intravenous diltiazem(10,30,100,300,1000 micro g/kg) produced dose-dependent depressor response in rabbits. Pressor responses to intravenous norepinephrine(10 micro g/kg) and phenylephrine (30 micro g/kg) were inhibited by pretreatment with intravenous diltiazem in rabbits and no difference was noted between the degree of both inhibitions of the pressor response by diltiazem. Pressor responses to intravenous norepinephrine (3 micro g/kg), phenylephrine (20 micro g/kg) and clonidine (300 micro g/kg) were inhibited by pretreatment with intravenous diltiazem in spinal rabbits. No difference was noted between the inhibition of norepinephrine-induced pressor response and that of phenylephrine-induced pressor response by diltiazem. The inhibition of clonidine-induced pressor response by diltiazem was slightly more prominent than that of norepinephrine-or phenylephrine-induced pressor response. These results suggest that diltiazem significantly inhibits both pressor responses mediated by alpha-1 and alpha-2 adrenoceptors

The In vitro drug susceptibility of 83 strains of Bordetella bronchiseptica recoverd from Korean pigs with atrophic rhinitis was investigated by the use of disk diffusion method. The majority of the organisms were highly resistant in order of prevalence to penicillin (98.7%), ampicillin(91.5%), streptomycin (90.3%), triple sulfa (83.1%), and trimethoprim/sulfamet-hoxazole (70.7%) while none of them were resistant to gentamicin, only 3.6% to colistin, chloramphenicol and kanamycin and 6.0% to tetracycline. The percentage of the organism resistant to bicozamycin, cephalothin and neomycin were 34.9%, 34.1% and 18.4%, respectively. A high prevalence of multiple drug resistance was observed and the 3 most common resistant patterns among 35 patterns noted were Am Pc Sm Sss Sxt(26.5%), Am Cf Pc Sm Sss Sxt(12%) and Am Bm Pc Sm Sss Sxt(9.6%) patterns

This study was performed to investigate the effect of gestation on the histological and histochemical changes of the uterine cervix of the native Korean cattle. A total of 110 cows obtained from the chonbuk abattoir were divided into six groups. The 1st group was of 9 non-pregnant cows and 101 singleton pregnant cows were grouped into 5 groups from pregnant I to pregnant V according to gestation periods by means of crown rump length measures. For light microscopy the tissues were fixed in 10% neutral formalin and processed routinely for paraffin sections. The 6um sections were taken and stained with H-E, Alcian blue pH 1.0, Alcian blue pH 2.5, Alcian blue pH 2.5/PAS, PAS reaction, toluidin blue, and trichrome. The cervical lengths and widths were increased in relation to advancing gestation. The cervical mucosubstance was composed of mixed mucopolysaccharides; the acid mucus was increased from the early pregnant state but the neutral mucus was found after pregnant IV, and the mucus was stained deeply in each staining in the fold cavity in according to gestation state.

Regional distribution and relative frequency of endocrine cells in ten portions of the gastrointestinal tract of the Korean native cattle were observed by immunocytochemical methods using specific antisera against chromogranin, serotonin, somatostatin, glucagon, bovine pancreatic polypeptide (BPP), motilin, gastric inhibitory polypetide (GIP), neurotensin, secretin, gastrin and substance P. In the abomasum, chromograin-, serotonin-, somatostatin-, motilin-, glucagon-, gastrin-, and substance P-immunoreactive cells were found. Chromogranin- and serotonin- and serotonin-immunoreactive cells were more numerous in the fundic region than pyloric region. Somatostatin- and gastrin- immunoreactive cells were numerous in the pyloric region than in the fundic region. In the large intestine, chromogranin-, serotonin- and BPP-immunoreactive cells were widely distributed and most numerous in the rectum. Somatostatin-, glucagon- and substance P-immunoreactive cells were rarely seen in the large intestine

This study was designed to elucidate the effects of iron, a well known catalyst of lipid peroxidation, on the contents of phospholipids, unsaturated fatty acids composed in phospholipid molecules and their derivatives, prostaglandins, and the composition changes of fatty acids contained in phospholipids. Iron decreased the contents of phospholipids and its components of unsaturated fatty acids. Catalytic action of iron decreased the composition rates of linoleate and linolenate composed in phospholipid molecules, while that of arachidonate was inclined to increase. The content of arachidonate was increased and that of prostaglandins was decreased without regard to increase the precursor of prostaglandins. It may be concluded that the decreases of the activities of prostaglandins and the increase of arachidonate are due to inhibition of the activities of enzyme systems responsible for prostaglandin synthesis by lipid peroxides produced by the catalyst of iron

Observations were made on the blood picture of 50 multiparous and 98 infertile cows. Mean values of RBC, Hb, PVC, MCV, MCH, MCHC and platelets for normal multiparous cows were 6.87+-0.84X10** (6)/mm** (3), 10.3+-1.3g/100ml, 31.4+-3.7ml/100ml, 46.1+-6.9u** (3), 15.3+-2.6pg, 34+-2.7%, and 372.7+-304.7X10** (3)/mm** (3) respectively. Mean values of RBC, Hb, PVC, MCV, MCH, MCHC and platelets for infertile cows were 7.00+-0.98X10** (6)/mm** (3), 10.6+-1.2g/100ml, 32.1+-3.6ml/100ml, 45.8+-6.7u** (3), 15.3+-1.8pg, 33.9+-3.3%, and 382.7+-157.5X10** (3)/mm** (3), respectively. Mean values of WBC count for normal multiparous and infertile cows were 7.92+-1.72 and 9.04+-2.87X10** (3)/mm** (3) respectively. In the differential leukocytes count, mean values of neutrophils, lymphocytes, monocytes, eosinophils and basophils for normal multiparous cows were 29.7+-7.9%, 56.8+-7.6%, 2.9+-1.9%, 9.9+-5.3% and 0.3+-0.7%, respectively, and mean values of neutrophils, lymphocytes, monocytes, eosinophils and basophils for infertile cows were 31.9+-7.8%, 57.5+-7.9%, 2.6+-1.9%, 7.5+-4.8%, and 0.4+-0.2%, respectively

In order to investigate the morphological characteristics of dendritic cells in the mammary gland of the mouse (C57 BL/6), rat (W), rabbit and cat, the fine structures of the dendritic cells have been observed by the electron microscope. The dendritic cells with the well-developed processes had an irregular shape, and lacked the desmosome. The pinocytotic vesicles and tubular invaginations of the cell membrane were frequently observed, and the mitochondria with the well-developed cristae were located in the restricted region in the cytoplasm of the dendritic cells. The nuclei of dendritic cells were indented. In the mice and rats, the dendritic cells had a few langerhans cell granules (Birbeck granules). From the above results, it is confirmed that the ATPase-positive dendritic cells in the mammary gland are the langerhans cells

Present study was undertaken in order to evaluate the lead contents of various feedstuffs produced in Korea and the effect of the burning of gasoline by automobiles on the lead contents. Ninty-one samples near and 95 far road were collected from 9 regions(Do). All of the samples were washed, dry-ashed and analyzed for lead content using atomic absorption spectrophotometer. The mean values obtained were checked for significance of difference using computer. The lead content in micro g/g of agriculture-byproducts were measured with the following mean values and ranges (in parenthesis). Rice bran:2.07+-1.67 (0-5.00), rice hull : 1.84+-1.18 (0-3.71), rice straw:1.27+-1.09(0-3.62), soybean pod; 4.55+-3.13 (1.13+-10.43), and wheat bran: 1.69+-0.86 (0-3.65). The lead content in micro g/g of pasture plants were measured with the following mean values and ranges. Kudzu:2.71+-1.74 (0.38+-8.75), leed: 2.03+-1.61 (0-4.54), lespedeza:4.73+-5.93 (0-31.25), sagebrush: 4.08+-3.75 (0-12.18), Korean-grass: 2.11+-1.38 (0-5.50), maizestalk: 2.62+-2.35 (0-8.65), clover: 3.83+-2.97 (0-12.19), alfalfa: 7.14+-0.97 (4.46-9.25), and timothy: 5.86+-4.79 (0-9.25). Fourteen samples (22.2%) out of 63 agriculture-byproduct samples and 42 (34.2%) out of 123 pasture plant samples showed lead content of more than 3 micro g/g which are said to be the upper limit value for cattle. No significant difference between the mean lead contents of near road, and those of far road was recorgnized. The regional mean values for all kinds of samples collected in Kyungbuk and Kyungnam were significantly (p0.05, p0.10) higher compared to those in Chungnam and Chejudo. From these results it may be concluded that the buring of gasoline by automobiles did not affect the lead contentes of washed feedstuffs produced in Korea at present

Twenty-eight porcine rotavirus were isolated from piglets with diarrhoea in Chonnam Province. According to the age, 41 to 60 day old pigs showed the highest isolation frequency among the post weaning pigs. The characteristics of the field isolates were determined by electronmicroscopy(EM), immunofluorescent assay(FA), and electrophoretic migration patterns of the genome profiles. Some of the isolates showed remarkable haemagglutination activity against rabbit and dog erythrocytes, ranging from 4 to 2848, respectively. At least 3 serotypes of porcine rotavirus were recognized by serum neutralization test using serotype specific rotavirus hyperimmune sera