Skins and hides are perishable resources that can be damaged by parasitic diseases and human error, which result in downgrading or rejection. This study was conducted to identify defect types and to determine their prevalence in pickled sheep and wet blue goat skins and wet blue hides. Each selected skin or hide was examined for defects in natural light and the defects were graded according to established quality criteria in Ethiopian standard manuals. Major defects were captured by digital photography. The major pre-slaughter defects included scratches (64.2%), cockle (ekek) (32.8%), wounds or scars (12.6%), lesions from pox or lumpy skin disease (6.1%), poor substance (5%), branding marks (2.3%) and tick bites (1.5%). The presence of grain scratches in wet blue hides (76.3%) was significantly higher than in pickled sheep (67.2%) and wet blue goat (59.1%) skins. The major slaughter defects included flay cuts or scores, holes, poor pattern and vein marks, with a higher occurrence in wet blue goat skins (28.7%; P < 0.001) than in wet blue hides (22.8%) and pickled sheep skins (11.1%). The most prevalent post-slaughter defects were grain cracks (14.9%), hide beetle damage (8%), damage caused by heat or putrefaction (3.7%) and machine-induced defects (0.5%). Grain cracks (27.04%) and hide beetle damage (13.9%) in wet blue goat skins were significantly more common than in wet blue hides and pickled sheep skins. These defects cause depreciation in the value of the hides and skins. Statistically significant (P < 0.001) higher rejection rates were recorded for wet blue hides (82.9%) than for pickled sheep skins (18.3%) and wet blue goat skins (8.5%). Improved animal health service delivery, effective disease control strategies and strong collaboration between stakeholders are suggested to enhance the quality of skins and hides.

Infectious and zoonotic disease outbreaks have been linked to increasing volumes of legal and illegal trade. Spatio-temporal and trade network analyses have been used to evaluate the risks associated with these challenges elsewhere, but few details are available for the pig sector in South Africa. Regarding pig diseases, Limpopo province is important as the greater part of the province falls within the African swine fever control area. Emerging small-scale pig farmers in Limpopo perceived pig production as an important means of improving their livelihood and an alternative investment. They engage in trading and marketing their products with a potential risk to animal health, because the preferred markets often facilitate potential longdistance spread and disease dispersal over broad geographic areas. In this study, we explored the interconnectedness of smallholder pig farmers in Limpopo, determined the weaknesses and critical control points, and projected interventions that policy makers can implement to reduce the risks to pig health. The geo-coordinates of surveyed farms were used to draw maps, links and networks. Predictive risks to pigs were determined through the analyses of trade networks, and the relationship to previous outbreaks of African swine fever was postulated. Auction points were identified as high-risk areas for the spread of animal diseases. Veterinary authorities should prioritise focused surveillance and diagnostic efforts in Limpopo. Early disease detection and prompt eradication should be targeted and messages promoting enhanced biosecurity to smallholder farmers are advocated. The system may also benefit from the restructuring of marketing and auction networks. Since geographic factors and networks can rapidly facilitate pig disease dispersal over large areas, a multi-disciplinary approach to understanding the complexities that exist around the animal disease epidemiology becomes mandatory.

Coxiella burnetii and Toxoplasma gondii are intracellular parasites that cause important reproductive disorders in animals and humans worldwide, resulting in high economic losses. The aim of the present study was to analyse the possible role of peridomestic small mammals in the maintenance and transmission of C. burnetii and T. gondii in the north-western African archipelagos of the Canary Islands and Cape Verde, where these species are commonly found affecting humans and farm animals. Between 2009 and 2013, 108 black rats (Rattus rattus) and 77 mice (Mus musculus) were analysed for the presence of Coxiella and Toxoplasma antibodies by enzyme-linked immunosorbent assay (ELISA) and indirect immunofluorescence (IFA), respectively. Our results showed a wide distribution of C. burnetii and T. gondii, except for T. gondii in Cape Verde, in both rodent species. The overall seroprevalence of C. burnetii antibodies was 12.4%; 21.1% for Cape Verde and 10.2% for the Canary Islands. With respect to T. gondii, seropositive rodents were only observed in the Canary Islands, with an overall seroprevalence of 15%. Considering the fact that both pathogens can infect a large range of hosts, including livestock and humans, the results are of public health and veterinary importance and could be used by governmental entities to manage risk factors and to prevent future cases of Q fever and toxoplasmosis.

Eight outbreaks of peste des petits ruminants in sheep and goats were reported in White Nile State, Sudan, between 2008 and 2009. A mortality rate of 4.2% was reported across the different outbreaks. Clinically the disease was characterised by high fever, ocular and nasal discharge, pneumonia, ulceration of the mucous membranes, diarrhoea and death. The postmortem findings included necrotic lesions in the mouth and gastrointestinal tract, and swollen, oedematous lymph nodes associated with the lungs and intestine. Of the 209 serum samples tested by competitive enzyme-linked immunosorbent assay, 113 (54%) were found positive. Peste des petits ruminants virus was confirmed in tissues, nasal swabs and blood samples by immunocapture enzyme-linked immunosorbent assay, reverse-transcription polymerase chain reaction and isolation of the virus in culture of lamb testicle cells.

Thoroughbred foal body temperature data were collected from shortly after birth until shortly after weaning during the 2007/2008 season on a stud farm in the Western Cape Province of South Africa. Equine encephalosis (EE) caused by EE virus (EEV) serotype 4 (EEV-4) occurred in the foal group during the first autumn after their birth (March and April 2008). A descriptive study was undertaken to provide data on the EEV maternal antibody status, the association between pyrexia and EEV infection, and the incidence of infection amongst the foals prior to and during the episode. This included the frequent capturing of foal body temperature data and regular collection of serum and whole blood during pyretic episodes. Infection by EEV was determined using both virological and serological methods. A high EE incidence of at least 94% occurred amongst the foal cohort, despite the fact that 37% of foals had previously shown maternal antibody to EEV-4. Pyrexia in foals was not directly associated with EE infection and 41% of infected foals showed no detectable pyretic episode. Information obtained from this EE episode showed the high incidence of EEV infection in foals during the first autumn after their birth. Monitoring foal body temperature can alert farmers to outbreaks of infectious disease, such as EE. These results are relevant to the epidemiology of EE and facilitate greater understanding of it as a differential diagnosis of African horse sickness (AHS), given that EE and AHS have similar epidemiologic profiles.

Avermectins and milbemycins are commonly used in agro-ecosystems for the control of parasites in domestic livestock. As integral members of agro-ecosystems with importance in maintaining pasture health through dung burial behaviour, dung beetles are an excellent non-target bio-indicator taxon for examining potential detrimental effects of pesticide application. The current review focuses on the relative toxicity of four different anthelmintics (ivermectin, eprinomectin, doramectin and moxidectin) in dung residues using dung beetles as a bio-indicator species. One of the implications of this review is that there could be an effect that extends to the entire natural assemblage of insects inhabiting and feeding on the dung of cattle treated with avermectin or milbemycin products. Over time, reduced reproductive rate would result in decreased dung beetle populations and ultimately, a decrease in the rate of dung degradation and dung burial.

The present study to evaluate the third degree burn involved all skin layers (full-thickness burns), and that by using ziziphus leaf extract and nigella seed extract as an ointment. Healthy twelve mature rabbits either sex, weighing 2-2.5 kg, bred locally were used. Divided in to two groups (ziziphus group and nigella group) six rabbits of rabbits each one burned experimentally by using fire source directly on skin surface and then treated with local application of ointment (ziziphus leaf ointment and nigella sativa seed ointment) each one on it is group with daily dressing by using medical gauze. This study appeared the benefit effect of ziziphus ointment and nigella ointment in burn healing in histopathological changes, but the group treated with ziziphus leaf extract (ointment) was better than the other group in cellular response to inflammatory process that occur during healing by early apparition of re-epithelialization

The trachea of the local sheep is a tubular structure that begins at the cricoid cartilage of the larynx and ends when it bifurcates to form the principle bronchi, composed of series of incomplete rings that were incomplete dorsally present between of them longitudinal folds. The study include twelve specimens divided into four groups grossly, histological study, cast and radiography. The anatomical study include the mean total tracheal length from the first ring to the bifurcation about (25.9 cm) , mean number of cartilaginous rings (48.6), mean number of folds (45), measured the length of trachea from the cricoids cartilage to the trachealis bronchus which enter to the cranial lobe of lung which branches from the trachea in last third before divided into two bronchi right and left each of one enter the lung for respiration also measure diameters of each tracheal ring which deference according the position of rings, which decrease of diameters when direction caudally to the root of lung the rings have different shape in the three parts of the trachea cervical, middle and thoracic the histological study showed the trachea lining pseudo stratified ciliated columnar epithelium with goblet cells, the wall of trachea consist of mucosa, submuosa, hyaline cartilage and adventitia and have large amount of tracheal gland,the trachealis muscle composed of elastic fibers interupted with smooth fibers. The cast of trachea showed the bronchial tree and radiography explain the trachea , bronchi and bronchioles.

The objective of present study was to investigate the gross and histopathological findings of calves kidneys slaughtered in Mosul abattoir. Pathological examination were carried out on fifty calves' kidneys. The most common gross lesions were included 20% multifocal white spots, 16% enlarged pale kidneys20% congested enlarged kidneys , 10% small shrunken kidneys, 14% hyperemic hemorrhagic kidneys, 20% kidneys without any gross lesions. The common observation in the histopathological examination of the kidneys revealed slight to severe mononuclear infiltration were commonly observed, widening of the Bowman's space were common, nephrosis, glomerulonephritis, interstitial nephritis, acute tubular degeneration and necrosis. Cysts were observed also in this study.

This study performed in twenty four male Sprague Dawley rats for (90) days which divided randomly into four equal groups. Group (1): received normal saline daily. Group (2): received orally codeine-paracetamol(40/2500 mg / kg b.w) daily. Group (3): received orally codeine-paracetamol (80/5000 mg / kg b.w)daily. Group (4): received orally codeine- paracetamol (160 /10000 mg / kg b.w) daily. After end of day (90) of study all animals were sacrificed to do the histopathological and biochemical examinations. The statistical analysis results revealed the body weight effects of codeine-paracetamol toxicity a significant (P≤0.05) decreases of treated group after (90) days of treatment. The histopathological investigation of liver, kidney and brain of treated groups showed centrolobular necrosis, dilation of sinusoids, vaculation of hepatocytes and septal fibrosis of liver while kidney showed vaculation of mesengial cells of glomeruli, necrosis of proximal convoluted tubules and dilation of renal cortical tubules, also brain of treated group showed vaculation of neurons, these changes are appeared mild in group (2), moderated in group (3) and sever in group (4). The statistical analysis results of biochemical investigations of liver and kidney function tests showed a significant (P≤0.05) increases of levels of serum AST, ALT, ALP, bilirubin and creatinine respectively in all treated groups which these enzymes increased mildly in group (2), moderately in group (3) and severely in group (4).