Displacement of the abomasum is one of the important incidence recorded in dairy cattle especially after calving that lead to huge economic loss. A six year old Holstein Friesian female cow calved fifteen days back was presented to the Large Animal Outpatient Unit, Teaching Veterinary Clinical Complex, Veterinary College and Research Institute, Namakkal with the history of not voiding dung and anorexia for past three days. The animal was fed with corn and ragi feed. Clinical examination revealed pale pink mucous membranes, right side distension of abdomen, ping sound on right paralumbar fossa to 11th intercostal space on simultaneous auscultation and percussion. On rectal examination balloon like structure was noticed and the liptak test revealed pH of 2. Ultrasonographic examination of abomasal contents and post mortem examination confirmed RDA.

Canine oral papillomatosis is a contagious and spontaneously regressing benign neoplastic disease of young dogs caused by canine oral papillomavirus. Six dogs of different breeds aged between 1-3 years were presented to Veterinary Clinical Complex with the history of wart like lesions in different parts of the oral cavity. Under Xylazine sedation and 10 % Lignocaine spray representative biopsy sample of wart was surgically excised. Autogenous vaccine was developed and mixed with formalin solution to in activate the virus. Dogs were subjected to inj. Autovaccine 1 ml through subcutaneous route once in a week for 5 weeks. Warts were completely regressed within 4 weeks period after autoimmune therapy. There was no recurrence of papillomatosis among the treated dogs during the follow-up period of 6 months and no adverse effects were recorded.

A primiparous Holstein Friesian crossbred cow was brought to VCC, VC&RI Namakkal with ventral swelling. Based on rectal examination and abdominal palpation it was diagnosed as right sided uterine torsion with prepubic tendon rupture. After the fetal delivery by caesarean section and proper postoperative care is given for a period of 10 days, life of the dam was saved.

The carcass characteristics of indigenous Siruvidai chicken were evaluated by sacrificing eight birds of each sex at 16 weeks of age. The results revealed that the mean pre-slaughter weight, New York dressed yield (%), eviscerated carcass yield (%) and ready to cook yield (%) in males (1006.98±10.87 g, 90.50±0.14, 65.11±0.40 and 70.83±0.42 %, respectively) were significantly (P<0.01) higher than females (825.21±5.90 g, 88.85±0.09, 62.77±0.33 and 68.41±0.34 %, respectively) and the overall mean values in the combined sex were 916.10±24.22 g, 89.67±0.23, 63.94±0.39 and 69.62±0.41 %, respectively. The mean blood loss and feather loss percentage were significantly (P<0.01) higher in females (4.28±0.05 and 6.87±0.08 %) than males (3.55±0.03 and 5.95±0.13 %) with the overall mean of 3.92±0.09 and 6.41±0.14 %, respectively. The giblets, gizzard, heart and liver yield of males (5.60±0.02, 2.33±0.01, 0.39±0.01 and 2.88±0.01 %, respectively) were significantly (P<0.05) lower than females (5.80±0.03, 2.42±0.01, 0.42±0.01 and 2.96±0.01 % respectively) with overall mean of 5.70±0.02, 2.38±0.01, 0.41±0.01and 2.92±0.01 %, respectively. The neck, back, breast, wing, thigh, drumstick yield percentage and meat-bone ratio of Siruvidai males (6.07±0.02, 22.60±0.18, 22.51±0.06, 12.16±0.21, 17.13±0.17, 15.21±0.17 % and 0.99) were significantly (P<0.01) higher than females (5.88±0.04, 19.91±0.21, 21.50±0.16, 11.53±0.18, 15.16±0.21, 13.43±0.39 % and 0.90, respectively) and the overall mean values in the combined sex were 5.98±0.03, 21.26±0.37, 22.01±0.15, 11.85±0.16, 16.15±0.28, 14.32±0.31 % and 0.95, respectively. The results of the present study provided base line information about the carcass traits of indigenous Siruvidai chicken ecotype under farm conditions.

Oxidative stress is a common mechanism contributing to initiation and progression of hepatic damage in a variety of liver disorders. Hence, there is a great demand for the development of agents with potent antioxidant effect. The aim of the present investigation is to evaluate the efficacy of raw and nanoforms of resveratrol and silibinin as a hepatoprotective and an antioxidant against diethylnitrosamine induced hepatocellular damage. 0.01% diethylnitrosamine administration to rats resulted in significantly elevated levels of lipid peroxidation (LPO) and decreased levels of superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPX), glutathione reductase (GSH) and total protein (TP) in the liver tissue. Post-treatment with the nano resveratrol (50 mg/kg), nano silibinin (50 mg/kg), raw resveratrol (50 mg/kg), raw silibinin (50 mg/kg) orally for 30 days significantly reversed the diethylnitrosamine induced alterations in the liver tissue and offered almost complete protection. The results from the present study indicate that both nano forms exhibit good hepatoprotective and antioxidant potential against diethylnitrosamine induced hepatocellular damage in rats as compared to raw forms.

Mammary tumours are considered as the most important neoplasms in dogs especially in sexually intact female dogs. Prognosis is directly associated with various factors such as tumour size, metastases, involvement of lymph node, tumour type and grade. Recently, tumour microenvironment (TME) has gained huge importance and proved to be a key regulator of breast cancer's biologic behaviour, according to mounting data. The capacity of extracellular matrix components like collagen to alter their intrinsic structure and alignment aids in tumour invasion and metastasis. We present a case study of 25 canine mammary tumours (CMTs), where the stroma associated with the malignancy was specifically considered while histomorphologically analysing the tumours. The majority of the tumours were malignant (96 per cent) and one was identified to be benign. Simple carcinomas made up the majority of tumours, followed by mixed types. Cancer associated stroma was assessed by routine H and E staining and additionally by performing immunohistochemistry technique with anti-cytokeratin antibody to access the relative abundance of neoplastic epithelial cells. Special stains such as Picrosirius red, Masson’s trichrome and Herovici were employed to demonstrate the desmoplastic stromal reaction and varying grades of collagen could be observed in the stroma of different tumours. The extent of fibroplasia was found to be directly proportional to the grade and size of tumour. Thus, results of the present study indicated that the cancer associated stroma significantly in fluence the CMT progression and clinical outcome.

A study was conducted in Murrah buffaloes belonging to Livestock Farm Complex of Veterinary College and Research Institute, Orathanadu, located in cauvery delta region to document the effect of heat ameliorative measures on physiological responses during summer. Twenty four buffaloes were selected and divided into four treatment groups of 6 animals per group. All the animals were maintained under standard managemental conditions with wallowing facility. The treatment group (T1) was control, animals in T2 were provided with cooling jacket, animals in T3 were supplemented with probiotics (Saccharomyces cerevisiae) and T4 animals received probiotics (Saccharomyces cerevisiae) and were provided cooling jacket. Physiological parameters viz., respiratory rate, pulse rate and rectal temperature were recorded during the summer season (March 2022 to May 2022) at weekly intervals in animals of all the treatment groups. Measurements were made when animals were at rest and after the exposure to sun light at 9 am and 2 pm respectively. From results it was concluded that the heat ameliorative measures given to the different groups of animals decreased the respiratory rate, pulse rate and rectal temperature during summer.

A one and half year old heifer was presented with a hard mass hanging from brisket region. The mass was oval shaped, 10 x15 cm in size, pedunculated with the base at the level of carpal joint. Cytological examination revealed melanocytes with the presence of numerous blackish melanin pigments in the cytoplasm. Histopathological examination revealed that the tumor was comprised of heavily pigmented spindle shaped cells, arranged in sheets with a large nuclei and abundant granular black pigment in the cytoplasm. Following surgical removal of the mass, the animal recovered with no recurrence. Based on clinical examination, cytology and histopathological findings, the growth was diagnosed as cutaneous melanoma.

A two year old non descript bitch was presented to the Department of Veterinary Surgery and Radiology, Veterinary Clinical Complex, Rajiv Gandhi Institute of Veterinary Education and Research, Puducherry with a history of an accidentall fall from the first floor of a building to the spiked metal railings of a gate onto the ground level. Physical examination revealed respiratory distress, pain on palpation around thoracic and abdomen region, perforating wound was noticed on the left lateral thorax at the level of 10 costal cartilage and animal was vomiting since then. On radiographic examination, a mild pneumothorax and gas filled air pockets were noticed in the abdomen, suspecting gastric perforation. Haematobiochemical values were within the normal range. Animal was stabilized by oxygen supplementation, IV fluids and analgesics. After stabilization, anaesthesia was achieved by Inj. Diazepam @ 0.5 mg/kg and Inj. Propofol @ 3 mg/kg IV. Exploratory laparotomy was performed to repair the perforating wound. Post operatively, antibiotics and analgesia were administered for 5th days along with fluid therapy. Based on history and clinical examination, the case was diagnosed as gastric perforation due to high rise syndrome and animal made an uneventful recovery.

The occurrence of the spirurid nematode, Pterygodermatites cahirensis in a Palm civet cat (Paradoxurus hermaphroditus) observed during necropsy is reported. The worms were found in the intestinal content. Male worms were small and slender compared to females. The worms had two rows of spines on the lateroventral sides along the whole length of the body. Males had short spicules. Females had uterus filled with developing ova. Eggs were thick-shelled with undifferentiated yolk mass.