In the conditions of the Republic of Belarus there was studied the influence of herbal infusion, tincture, liquid and dry extracts of elecampane (Inula helenium) on morphological and biochemical indexes of pig blood. In course of the study it was established, that preparative forms of elecampane stimulated the formation of blood corpuscle, and also increased of the hemoglobin level in blood of pigs. Administration of elecampane preparations did not cause any authentic changes in blood leukogram of swine; all indicators were within normal limits. Elecampane preparations did not cause changes on the part of biochemical blood indexes of and did not influence the activity of enzymes. Research results showed that herbal infusion, tincture, liquid and dry extracts of elecampane did not render negative influence on swine.

In the conditions of the Republic of Belarus there were studied the anthelminthic properties of preparative forms of elecampane (Inula helenium) (herbal infusion, tincture, liquid and dry extracts). Research results showed that the analyzed preparative forms in the administrated doses possesed high therapeutic efficiency against strongyloidosis and strongylatosis of gastroenteric path of sheep. Thus, according to results of research it was established, that the highest therapeutic effect rendered herbal infusion of elecampane in a dose of 6 ml/kg live weight once a day three days continuously; and the antiparasitic efficiency was 60%. Application of elecampane tincture in a dose of 1 ml/kg live weight once and 0,5 ml/kg of live weight twice rendered the 100% therapeutic effect. Administration of a liquid extract of elecampane in a dose of 0,2 ml/kg live of weight once and 0,1 ml/kg of live weight twice rendered 100% therapeutic effect. Application of elecampane dry extract in a dose of 30 mg/kg of live weight once and 25 mg/kg of live weight twice rendered 100% therapeutic effect.

In the conditions of the Republic of Belarus there were studied the aetiology factors in development of dermatoses of productive cows taking into account the hygienic aspects. Structural defects of floors of cattle livestock buildings in animals of an experimental group promoted higher (on 35%) development of mattery dermhelminthiasis of distal areas of hindlegs in comparison with animals of a control group. Occurrence of skin dermhelminthiasis, especially in distal areas of hindlegs, was caused by various primary traumas of soft parts with the subsequent introduction into them of pathogenic microbial flora. The imperfect design of floors, an unsatisfactory microclimate in cow cattle houses, hypodynamia in the absence of constitutional walk made the preconditions for it. The reasons of purulent dermatosis of cows were two interconnected etiological factors: mechanical damages of tissues and development of a surgical infections in affected areas against the background of unsatisfactory microclimate that led to decrease in dairy efficiency on 4,51%. Therefore in a complex of the actions directed towards the preventive maintenance of surgical diseases, it is necessary to include the strict control over designing, building and operation of cattle-breeding premises, traumatism prevention, creation of an optimum microclimate and observance of zoohygienic norms of cattle maintenance.

In the conditions of the Republic of Belarus there were determined the parameters of acute and subacute toxicological characteristics of the developed in the Vitebsk State Academy of Veterinary Medicine anthelmintic preparations of durable action Febolvetum-О for control of sheep strongylatosis and Febolvetum for control of strongylatosis of cattle young stock. Data on determination of toxicological parameters of the prolonged action bolus were presented. Research results showed that the preparations did not render negative influence on laboratory animals (white mice). According to the parameters of acute oral toxicity the Febolvetum was qualify as the third hazard class. In accordance with the results of study of subacute toxicity parameters of the preparations, it was concluded, that in the conditions of free feeding of Febolvetum boluse in combination with forages in course of 30 days in doses of 200 mg/kg; 150 mg/kg; 100 mg/kg of body weight in animals there were found no signs of intoxication; there were not stated any is not fixed deviations in physiological state; and were stated no mice death.

In the conditions of the Republic of Belarus there were studied biochemical indexes of calf blood serum against the background of application of probiotic preparations Bilavet C. Results of research showed that administration of probiotic preparations from the first day till the six day and from the fourteenth day till the nineteenth day of calf life with the preventive purpose rendered the simulative influence on indexes of natural resistance, which were accompanied with the increasing of total protein quantity in blood on 2,9-5,9%, as well as the increasing of protein fractions, in particular, globulin-rich fraction on 4,2-6,4%. Administration of probiotic preparation Bilavet С to calves rendered the positive influence on blood biochemical indexes, promoted the uptaking and better accumulation of mineral substances: content of crude calcium, inorganic phosphorus, magnesium, iron increased on 15,3%, 10,5%, 13,2% and 3,6%, respectively.

In the conditions of the Republic of Belarus there was studied a state of lipid peroxidation, antioxidant protection and activity of hepatospecific enzymes of blood plasma of piglets. Research results showed that weanling piglets which had low body weight in the conditions of industrial breeding technology were characterized by high intensity of processes of lipid peroxidation. At the same time, the antioxidant system reacted adequately to the mentioned above changes. There was noted a high dependence between the content of Schiff's bases which were the end-products of lipid peroxidation processes, and the activity display of amplifier hepatospecific enzymes of blood plasma of weanling piglets. The received results of research can be used for estimation of a condition of prooxidant and antioxidant status, and in a complex with data on activity of sorbitol dehydrogenases, isocitratdehydrogenases and glutamatedehydrogenases - for an estimation of a functional state of a liver of weanling piglets with low body weight at an initial stage of their breeding.

In the conditions of the Republic of Belarus there was studied the antihelmintic characteristics of the preparative forms of marsh cinquefoil (Comarum palustre): herbal infusion, infusion, liquid, extract, pulvis. The research has shown that these preparative forms in the specified dozes had a rather high therapeutic efficiency against strongylatosis of gastro-intestinal tract of young ruminants. The highest therapeutic effect was rendered by a liquid extract of Comarum palustre after its administration to animals in a dose of 0,2 ml/kg twice with 24 hour interval. In this case during the strongylatoses of a gastroenteric tract the antiparasitic intensefficiency of sheep and cattle by the end of experience was 98,1% and 97,3% respectively, and antiparasitic extensefficiency was 90% for both kinds of animals. After herbal infusion application of Comarum palustre for animals (in a dose of 7 ml/kg of live weight before feeding once a day within 3 days continuously) by the end of the 14 day of the experiment made it possible to obtain intensefficiency of 70% for both animal species, and extensefficiency of 60% for sheep and 70% - at calves. Tincture application of marsh cinquefoil for animals in a dose of 1 ml/kg of live weight of twice with 24 hours interval, provided the intensefficiency of 85% for sheep and 84% - for cattle, and extensefficiency of 70% and 80%, respectively. In the conditions of application of a pulvis of marsh cinquefoil in a dose of 500 mg/kg of live weight twice with 24 hours interval, made it possible to obtain the 63,4% intensefficiency for sheep and 67,8% - for calves, and extensive efficiency - 50% and 40%, respectively.

In the conditions of the Republic of Belarus by an example model of a purulent wound at rats there was realized an experimental study of pharmacological activity of a medical remedy PhytoMP (containing active substances of Macleaya microcarpa (Maxim.) Fedde of Papaveraceae family; and Plantago major L. of Plantaginaceae family) in the form of powder. It was established, that the intensity wound-healthing effect depended on a ratio of the components plume poppy / greater plantain 1 + 1:1, 2:1, 1:2. Studying of the remedy safety showed that PhytoMP in the maximal dozes was not toxic for animals after a single unitary intragastric administration in dose of 50000 mg/kg to mice and in dose of 20833 mg/kg to rats. The mentioned above indexes surpassed the recommended for human dose after application tonsilles (1,428 mg/kg) in 35014 and 14589 times, and also the recommended for human doses for application at a wound with size of 2x2 square cm (11,424 mg/kg) - in 4377 and 1824 times, respectively.

The Republican Agricultural Breeding Unitary Enterprise Zarechje of the Republic of Belarus is the basic horse-breeding enterprise of Belarusian coach horse breeding. In the enterprise there are 27 mares and 2 studhorses; all animals are purebred. It is established, that unaltered male horses and mares belong to Belarus coaching breed, all pedigree animals have a high class: 15 horses belong to an elite class that makes 75% from all herd, 4 heads concern the first class (20%), and 1 head – to the second class (5%). Measurements surpass the standard that can prove the appropriate selection and breeding work in the enterprise. After studying the measurements of studhorses of the enterprise in comparison with the standard it was established, that the height at crest of stallions on the average exceeds the breed standard on 30%, slanting length of a trunk - on 5,0%, a breast grasp - on 4,0% and a metacarpus grasp - on 6%. For improvement of herd of horses it is necessary to organize correctly a coupling campaign with drawing up of the coupling plan and selection of a uterus to stallions; to use in copulation only the best elite stallion.

In the conditions of Vitebsk region of the Republic of Belarus there was realized a programme on creation of breed type of Hereford cattle. In course of the study there were realized experiments on increasing the number of livestock of beef cattle breeding by means of accumulation cross breeding of black-and-white cattle with Hereford producer bulls as well as by means of pedigree breeding of Hereford cows and calves imported from Russia and Hungary for the production of marbled beef. Breeding background of obtained purebred calves was determined by DNA-testing method in accordance with the international standard of certification. Into the breeding group of created meat type of Hereford cattle in the analyzed cattle breeding enterprise there were selected 1183 heads, including 24,2% of purebred animals and 17,2% hybrids of the third and fourth generations. The breeding estimation thoroughbred Hereford cattle showed that all producer bulls belonged to the class elite-record. The percentage of cows and heifers of the elite-record class was 89,3% in the conditions of growing number of a thoroughbred livestock on 98 heads. Purebred young stock in number of 45 heads and their mother passed the estimation of their origin by DNA method-testing.