It was established that in blood serum of pigs vaccinated against leptospirosis there was an authentic increasing of alanine aminotransferase, alkaline phosphatase and gamma-glutamyltransferase that made proved the presence of residual reactogenicity of biological preparations. In course of the experiment there were used 4 groups of swine which were administrated with 4 types of vaccines: 1. polyvalent vaccine produced in Belarus; 2. experimental thiosulfate vaccine in which there was used 30% sodium solution; 3. experimental emulsified vaccine; experimental emulsified + sodium + thiosulfate vaccine.

Development of a production technology of a national anthelminthic preparation Triclafen (from benzimidazole group) on the basis of triclabendazole and fenbendazole was realized in the conditions of the Republic of Belarus. As a result of realized experiments it was found that the developed suspension corresponded the requirements of pharmacopoeial items and can be applied for veterinary practice. Composition of different components with wide action spectrum made it possible to apply it against ruminant animals.

This article is devoted to a problem of biochemical interaction of selenium and antioxidational system of animals and people organism. The problem we have touched is about the efficiency of influence of organic and inorganic taking place on subcellular level. The advantages of organic selenium are proved, the degree of its bjochemical influence on an antioxidationi status of health are indicated.

Analysis of national studies and literary sources on problems of haemophilus pleuropneumoniae of swine was realized in the conditions of the republic of Belarus. Research was realized in the conditions of Agricultural Production Co-operative Uritskoe (Gomel region, Belarus). It was established that medical actions gave positive result only at early stages of disease.

Economic efficiency of immunization of piglets with a vaccine against a salmonellosis, pasteurellosis and streptococcosis in combination with 20% solution of sodium thiosulfate and Vitamin С as immune stimulators was analyzed in the production conditions of the Republic of Belarus.

In the conditions of the Republic of Belarus there was developed a production technology and there were produced samples of lyophilizated live vaccine against Aujeszky's disease of swine which corresponded to all parameters of control. The vaccine had an expressed phylactic power, induced the development of long-lived immunity of vaccinated piglets.

Comparative effectiveness of application of SV-1 and SV-2 sorbents for preventive treatment of abomazoenterite of 1-2 month old calves was studied in the conditions of the Republic of Belarus. Research results showed that application of SV-1 and SV-2 sorbents rendered a positive influence on hematological and biochemical blood indexes, in particular, there was an increasing of hemoglobin level, albumins content, alkaline reserve, calcium and phosphorous in blood serum. They also rendered the stimulatory effect on natural resistance. The prophylactic effectiveness in experimental group was 100%, in a control one – 60%.

Development of axial skeleton bones of meat type broiler chickens of Kobb-500 and Ross-308 crosses at the postnatal ontogenesis period was investigated in the conditions of the Republic of Belarus. In course of studies there were used broilers of 5 age groups (1 day old, 20 days old, 30 days old and 40 days old) which were selected in accordance with analogous principle with 10 heads per each group. Research results showed that live weight gain as well as axial skeleton weight gain of both crosses chickens increased wavily. The highest growth intensity of body weight and axial skeleton weight was stated at broiler chickens of Kobb-500 cross at the last age period. The opposite way, there was noted the increasing of axial skeleton growth for broiler chickens of Ross-308 cross at the age of 20 days. At the further age periods till the end of fattening-off there was stated the slowing of axial skeleton and body weight. In the period of 1 to 10 days there was stated an intensive growth of cervical spine of spinal column of broiler chickens of both crosses. High intensity of absolute weight growth of cervical spine of spinal column for Kobb-500 cross chickens was stated at the age period 30-40 days; for Ross-308 cross chickens - at the age 10-20 days

In degree incest negative influence of inbreeding is established on sheep's productive qualities in comparison with contemporaries with inbreeding in a degree of a close and moderate alliance. The system of a coupling of the wombs is developed, excluding inbreeding depression on productive qualities of animals and allowing to carry out repairs a livestock in a small population due to own reproduction

Usage of biological preparation of high antibacterial activity allows to decrease the air pollution by bacteria of colon bacillus group at 25-100%, increase productivity at 17-67 g, safety – at 0,4%, resistance, protein metabolism, protein fractions and some other indices (lysozyme and betalysine activity, leucocytes, erythrocytes, hemoglobin, calcium, phosphorus, iron, magnesium, AST, ALT, urea, cholesterol, bilirubin and glucose)