A total number of 50 genital tracts were collected from cows slaughtered at “Belefia” abattoir in “Beni-Suef” governorate, Egypt. The genitalia were inspected grossly and the ovarian activity was noticed. Tissue specimens were taken from the tips of uterine horns, fallopian tubes, ovaries of both sides. The fallopian tubes were cut and sampled at three levels namely, infundibulum, ampulla, isthmus. All tissue specimens were fixed in 10% formalin solution, embedded in paraffin wax, sectioned at 5 μm and stained with hematoxylin and eosin stain (Bancroft and Stevens 1996) and examined microscopically. The pathological changes in the fallopian tube in relation to lesions in the uterus and ovarian activity were investigated. The uterine pathological lesions were endometritis (12%), adenomyosis (12%), and cystic glandular hyperplasis (8%). Inflammation of the fallopian tube salpingitis, was graduated as mild degree(18%), moderate degree(2%), and severe degree (2%). The intraepithelial microcysts of the uterine tube represented 8% of the examined cases.

The sensory quality attributes of coated and uncoated beef burger patties formulated with texture soy granules or vegetables (peas and carrots) were studied in comparison to that of the control ones. Incorporation of textured soy granules significantly reduced the color, marbling, appearance, flavor, tenderness, juiciness, taste and overall acceptability in comparison with either control or vegetable extended burger. Addition of peas and carrots to uncoated burger significantly reduced the binding scores in raw samples, as well as flavor and juiciness in cooked samples, however, no significant differences could be observed in the other sensory attributes in both raw and cooked products. Vegetable extended burger had the highest cooking loss percent (20.14), followed by control samples (17.83), while soy extended product had the lowest value (15.82%). Application of batter and breading to vegetable extended burger significantly improved the investigated sensory parameters in comparison with the uncoated samples. On the other hand, application of batter and breading to soy extended burger revealed no improvement in the sensory quality attributes in both raw and cooked samples. Addition of soy granules and vegetables significantly increased the moisture, ash and carbohydrate and reduced the fat content of raw burger patties. Moreover the incorporation of textured soy significantly increased the protein content.

Freshwater snails collected from ditch like ponds near the River Nile in Beni-Suef Governorate during three climatically differed periods. Lymnaea cailliaudi, Biomphalaria alexandarina, Bulinus truncatus, Lanistes carinatus, Cleopatra bulimoids,Physa acuta, Viviparus viviparus, Melania tuberclata and Bivalves species were included. The total number of collected snails in December 2008, March 2009 and July 2009 were 1321, 1370 and 1211 respectively, with larger number in March than in July or December due to optimal climatic conditions in Marsh for most of collected snails. The recorded survival longevity in the laboratory was more than 90 days for Lymnaea cailliaudi, two months for Lanistes carinatus, while in Melania tuberclata, was about three weeks but only two to three days for Bivalves. Cercariae shedding observed from Lymnaea, Lanistes and Biomphalaria species beside stylet cecariae from Lymnaea and Lanistes snails, also rediae and sporocysts were found in crushed snails in all periods of collections with little difference between these periods, about 14% of crushed Lymnaea were containing rediae. Aquatic insects and their larvae were found especially water bug Sphaerodema sp. found predating snails or their eggs, also the mature insect still alive in the breeding container all over the period of the experiment more than three months. Culex larvae attacked egg masses of the snails, estacosa predated the snails while Telapia nilotica fishes showed low affinity to predate such snails. The oleo-gum resin Myrrh (Commiphora molmol) in the concentration of 0. 5gm/1 litre water killed 90 % of the exposed snails after 72 hours.

Broiler breeder Lohmann chickens aged 39 weeks received 3 doses each 0.2 ml of the inactivated oil emulsion AI- H9N2 vaccine, at the 2nd, 7th and 15th weeks of age by subcutaneous injection. The individual HI values of the tested samples were homogenous as their SD values were lower. All breeder and progeny sera were positive (100- 66.7%) at weeks 40- 46 weeks of age. Correlation between parents and progeny HI antibody levels was 0.95. Progeny/Parents HI antibodies percentage were ranged from 54.9 to 65.2%. Correlation between parents and progeny ELISA and HI antibody levels were 0.91 and 0.60- 0.65; respectively. The detected HI antibody titres at the 3rd day of age were slightly increased than that of the 1st day titres followed by gradual decrease to be apparently negative at the 12th -21st day of age in comparison to the original levels. The tested groups for Antibodies to H9 by ELISA test were still detected to 21- 27 days of age of progeny. The half-life time of maternal antibodies expressed as loss of one HI log 2 between groups was ranged from 3.3- 7.2 days; with average 5.1- 5.6 days. Half life time by ELISA titre was in average of 8.9 days. Correlations between HI and ELISA ranged from 0.83-0.94. We concluded that both HI and ELISA tests are of the same value in detection of AI antibodies and first vaccination of broiler chicks with maternal antibodies against AI H9N2 must be done after the 6th day of age.

The pharmacokinetic aspects of cephradine were studied after intravenous (IV), intramuscular (IM), subcutaneous (SC) and oral administration of a single dose of 50 mg kg-1 b.wt. in chickens. Tissue distribution and residues of cephradine after repeated oral administration for 5 consecutive days were also estimated. After IV injection of cephradine in a dose of 50 mg kg-1 b.wt., the serum concentration time curves were best described by a two compartment-open model. The drug was rapidly distributed with a distribution half-life (t0.5(α)) of 0.120 h and apparent volume of distribution (Vdss) was 2.187 L kg-1. The drug was rapidly eliminated with a half-life of elimination (t0.5(β)) of 1.047 h and the body clearance (ClB) was 2.35 L kg-1 h-1. The drug was rapidly absorbed after IM, SC and oral administration as indicated by short half-lives of absorption (t0.5(ab)) of 0.154, 0.364 and 0.65 h., respectively. While the elimination half-lives (t0.5(el)) and systemic bioavailabilities were 0.859, 2.652, 1.74 h and 59.386, 84.5, 97.97 %, respectively. Repeated oral administration of cephradine (50 mg kg-1 b.wt twice daily) for 5 consecutive days caused no change in serum enzyme activities of ALT and AST but induced a significant increase in serum uric acid concentration at 72 to 120 hours post administration.

In a trial for comparison between the efficiency of single fowl pox (FP) vaccination and the efficiency of each combined FP and Avian encephalomyelitis (AE) vaccination and simultaneous vaccination with FP and Reo and with FP and Chicken anemia virus (CAV) vaccines our conclusion was that there is no antagonistic reaction between FP virus strain and each AE, Reo and CA viruses strains. In addition, humoral immune response against AE virus strain in case of combined AE+FP vaccination is markedly potent than that in case of single AE vaccination, more over the value of average EID50 of AE virus strain in several batches of combined AE+FP vaccines is significantly higher at P > 0.05 than that in several batches of single AE vaccines. On the other hand, immune response against FP virus strain and Reo virus strain in case of simultaneous vaccination with FP and Reo vaccines is higher than that in case of single FP vaccination and single Reo vaccination. Consequently, it is advisable to use combined live attenuated AE+FP vaccine instead of vaccination with single FP and AE separately. Also, application of simultaneous vaccination with FP and Reo vaccines is advisable as it is proved to be more beneficial than vaccination with each vaccine separately specially in case of that FP vaccine of low potency.

The present study aimed to clarify the light and electron microscopic structure of the prostate gland of mature (one-humped camels) during different seasons of the year. Glands of seventy-two mature healthy animals (5-7 years old) were collected from the Cairo slaughter house during one year, (6 samples each month) and prepared to be studied microscopically by the light and electron microscope. The prostate gland was found to be consisted of an external dorsal part dorsal to the neck of the bladder and an internal part situated in the submucosa of the prostatic urethra. During active season (winter and spring), the corpus prostate was enveloped by a thick fibromuscular capsule which sent septa, to divide the gland into lobules. The parenchyma formed of compound tubuloalveolar adenomeres. The alveoli and tubules were lined by high columnar cells and few basal ones. The acini appeared at different stages of secretory activity (synthesis, storage, secretion and exhaustion). Ultrastructurally, the acinar cells contained well developed rough endoplasmic reticulum (rER), numerous mitochondria and a variable number of secretory granules. The duct system began as central collecting sinuses lined by simple columnar secretory epithelium. The pars interna occurred in the submucosa of the prostatic urethra enveloped by a thick fibro-muscular band. The branched tubuloalveolar parenchyma contained adenomeres lined with simple cuboidal epithelium. During the inactive season (summer and autumn), the stroma showed a marked proliferation of the fibromuscular tissue on the expense of the parenchymatous tissue. The adenomeres became very small or even rudimentary with narrow lumina devoid of secretory materials. Marked reduction in the cytoplasmic organelles with a total absence of the secretory granules was also pronounced.

A study was performed on fifty normal goats for radiographic (only 20 animals), and sonographic (the all 50 animals) investigations. Radiographic results revealed that, both kidneys had bean shaped and smooth contour. The right kidney position was constant due to its relation with the liver, while, the left kidney was mobile and its position varied according to the degree of fullness of the rumen due to its long mesentery. The sonographic results revealed the position, shape, dimensions and echogenicity of kidneys, by using 3.5/5.0 MHz curved transducer and 6.0/8.0 MHz linear transducer. The renal capsule was represented by a very fine echogenic lines around the kidney that couldn’t be distinguished from the peri-renal fat. The cortex was more echogenic than the medulla and had uniform finely granular hypoehoic pattern. The corticomedullary junction was slightly more echogenic than the cortex due to the presence of the arcuate arteries. The medulla was observed as hypoechoic area interrupted by bright echogenic lines representing the recesses and interlobular arteries that gave the appearance of typical medullary pyramids. The dimensions of the right kidney were 5.32 ± 0.12, 2.79 ± 0.07, 0.64 ± 0.01, 1.52 ± 0.03, 2.74 ± 0.09, 1.27 ± 0.06, 1.25 ± 0.05, and 1.72 ± 0.09; and the dimensions of the left kidney were 5.34 ± 0.12, 2.80 ± 0.07, 0.65 ± 0.01, 1.55 ± 0.03, 2.76 ± 0.09, 1.26 ± 0.06, 1.28 ± 0.05, and 1.73 ± 0.1, for the length, width, cortical thickness, medullary thickness, depth, diameter of renal sinus, diameter of renal parenchyma, and circumference of renal pyramids respectively.

This study was designed to determine whether toluene abuse affected the organs function or general health of males and females. In this study used 24 rabbits of both sex , the animals were divided in four groups , six animals in each group ,the animals were exposed to toluene vapor inhalation ( 500 ppm / 2h/day ) daily for 2 months.Exposure –related suppression of body weight gain and food consumption were observed. Salivation and lacrimation were observed during exposure periods .The pathological changes these were showed organs have simple different between the males and females. The pathological changes observed in the lungs of males are emphysema, infiltration of lymphocytes in alveolar wall , thickness of alveolar wall ,and hemorrhage ,similar to that in female .The pathological changes observed in the kidney of females observed fatty degenera- tion and cloudy swelling ,while in the males cloudy swelling only. The pathological changes observed in the liver of females observed hydropic degeneration , while in the liver of males hydropic degeneration , congestion of blood vessels ,and infiltration of inflammatory cells (lymphocytes).The pathological changes observed in the uterus of females observed fibrosis, oedema , degeneration of the cells lining the uterine gland ,and red blood cells with inflammatory cells.

The aim of this study was to investigate the clinical signs and histopathological changes of acute toxicity of ivermectin in the centeral and peripheral nervous system liver, kidney, pancreas and heart of pigeons after s/c injection with ivermectin .Eighteen bird were divided into three equal groups.Group A were injected with 8mg,group B were injected with 10 mg and group C served as control group.The results showed markedy reduced of water and food consumption ,somnolence and death of treated pigeons.Nervous signs were restlessness, ataxia, un steady gait, tremor and recumbent. The histopathological changes included degeneration of nerve fibers of spinal cord and sciatic nerve .Degeneration , necrosis and vacuolation were noticed in liver, kidney and heart,as wll as proliferation of bile duct was also seen in liver.