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Ambient carbon monoxide associated with alleviated respiratory inflammation in healthy young adults
2016
Zhao, Zhuohui | Chen, Renjie | Lin, Zhijing | Cai, Jing | Yang, Yingying | Yang, Dandan | Norbäck, Dan | Kan, Haidong
There is increasing controversy on whether acute exposure to ambient carbon monoxide (CO) is hazardous on respiratory health. We therefore performed a longitudinal panel study to evaluate the acute effects of ambient CO on fractional exhaled nitric oxide (FeNO), a well-established biomarker of airway inflammation. We completed 4–6 rounds of health examinations among 75 healthy young adults during April to June in 2013 in Shanghai, China. We applied the linear mixed-effect model to investigate the short-term associations between CO and FeNO. CO exposure during 2–72 h preceding health tests was significantly associated with decreased FeNO levels. For example, an interquartile range increase (0.3 mg/m³) of 2-h CO exposure corresponded to 10.6% decrease in FeNO. This association remained when controlling for the concomitant exposure to co-pollutants. This study provided support that short-term exposure to ambient CO might be related with reduced levels of FeNO, a biomarker of lower airway inflammation.
Show more [+] Less [-]Human exposure to environmental health concern by types of urban environment: The case of Tel Aviv
2016
Shnell, Itzhak | Potchter, Oded | Yaakov, Yaron | Epstein, Yoram
This study classifies urban environments into types characterized by different exposure to environmental risk factors measured by general sense of discomfort and Heart Rate Variability (HRV). We hypothesize that a set of environmental factors (micro-climatic, CO, noise and individual heart rate) that were measured simultaneously in random locations can provide a better understanding of the distribution of human exposure to environmental loads throughout the urban space than results calculated based on measurements from close fixed stations. We measured micro-climatic and thermal load, CO and noise, individual Heart Rate, Subjective Social Load and Sense of Discomfort (SD) were tested by questionnaire survey.The results demonstrate significant differences in exposure to environmental factors among 8 types of urban environments. It appears that noise and social load are the more significant environmental factors to enhance health risks and general sense of discomfort.
Show more [+] Less [-]Multifaceted toxicity assessment of catalyst composites in transgenic zebrafish embryos
2016
Jang, Gun Hyuk | Lee, Keon Yong | Choi, Jaewon | Kim, Sang Hoon | Lee, Kwan Hyi
Recent development in the field of nanomaterials has given rise into the inquiries regarding the toxicological characteristics of the nanomaterials. While many individual nanomaterials have been screened for their toxicological effects, composites that accompany nanomaterials are not common subjects to such screening through toxicological assessment. One of the widely used composites that accompany nanomaterials is catalyst composite used to reduce air pollution, which was selected as a target composite with nanomaterials for the multifaceted toxicological assessment. As existing studies did not possess any significant data regarding such catalyst composites, this study focuses on investigating toxicological characteristics of catalyst composites from various angles in both in-vitro and in-vivo settings. Initial toxicological assessment on catalyst composites was conducted using HUVECs for cell viability assays, and subsequent in-vivo assay regarding their direct influence on living organisms was done. The zebrafish embryo and its transgenic lines were used in the in-vivo assays to obtain multifaceted analytic results. Data obtained from the in-vivo assays include blood vessel formation, mutated heart morphology, and heart functionality change. Our multifaceted toxicological assessment pointed out that chemical composites augmented with nanomaterials can too have toxicological threat as much as individual nanomaterials do and alarms us with their danger. This manuscript provides a multifaceted assessment for composites augmented with nanomaterials, of which their toxicological threats have been overlooked.
Show more [+] Less [-]Physiological and genotype-specific factors associated with grain quality changes in rice exposed to high ozone
2016
Jing, Liquan | Dombinov, Vitalij | Shen, Shibo | Wu, Yanzhen | Yang, Lianxin | Wang, Yunxia | Frei, Michael
Rising tropospheric ozone concentrations in Asia affect the yield and quality of rice. This study investigated ozone-induced changes in rice grain quality in contrasting rice genotypes, and explored the associated physiological processes during the reproductive growth phase. The ozone sensitive variety Nipponbare and a breeding line (L81) containing two tolerance QTLs in Nipponbare background were exposed to 100 ppb ozone (8 h per day) or control conditions throughout their growth. Ozone affected grain chalkiness and protein concentration and composition. The percentage of chalky grains was significantly increased in Nipponbare but not in L81. Physiological measurements suggested that grain chalkiness was associated with a drop in foliar carbohydrate and nitrogen levels during grain filling, which was less pronounced in the tolerant L81. Grain total protein concentration was significantly increased in the ozone treatment, although the albumin fraction (water soluble protein) decreased. The increase in protein was more pronounced in L81, due to increases in the glutelin fraction in this genotype. Amino acids responded differently to the ozone treatment. Three essential amino acids (leucine, methionine and threonine) showed significant increases, while seven showed significant treatment by genotype interactions, mostly due to more positive responses in L81. The trend of increased grain protein was in contrast to foliar nitrogen levels, which were negatively affected by ozone. A negative correlation between grain protein and foliar nitrogen in ozone stress indicated that higher grain protein cannot be explained by a concentration effect in all tissues due to lower biomass production. Rather, ozone exposure affected the nitrogen distribution, as indicated by altered foliar activity of the enzymes involved in nitrogen metabolism, such as glutamine synthetase and glutamine-2-oxoglutarate aminotransferase. Our results demonstrate differential responses of grain quality to ozone due to the presence of tolerance QTL, and partly explain the underlying physiological processes.
Show more [+] Less [-]Characterization and source apportionment of PM2.5-bound polycyclic aromatic hydrocarbons from Shanghai city, China
2016
Wang, Qing | Liu, Min | Yu, Yingpeng | Li, Ye
Polycyclic aromatic hydrocarbons (PAHs) were studied in 230 daily fine particulate matter (PM2.5) samples collected in four seasons at urban and suburban sites of Shanghai, China. This study focused on the emission sources of PAHs and its dynamic results under different weather conditions and pollution levels and also emphasized on the spatial sources of PM2.5 and PAHs at a regional level. Annual concentrations of PM2.5 and 16 EPA priority PAHs were 53 μg/m3 and 6.9 ng/m3, respectively, with highest levels in winter. Positive matrix factorization (PMF) modeling identified four sources of PAHs: coal combustion, traffic, volatilization and biomass combustion, and coking, with contributions of 34.9%, 27.5%, 21.1% and 16.5%, respectively. The contribution of traffic, a local-indicative source, increased from 17.4% to 28.7% when wind speed changed from >2m/s to <2m/s, and increased from 18.3% to 31.3% when daily PAH concentrations changed from below to above the annual mean values. This indicated that local sources may have larger contributions under stagnant weather when poorer dispersion conditions and lower wind speed led to the accumulation of local-emitted pollutants. The trajectory clustering and potential source contribution function (PSCF) and concentration weighted trajectory (CWT) models showed clearly that air parcels moved from west had highest concentrations of PM2.5, total PAHs and high molecular weight (HMW) PAHs. While small differences were found among all five clusters in low molecular weight (LMW) PAHs. Sector analyses determined that regional transport source contributed 39.8% to annual PM2.5 and 52.5% to PAHs, mainly from western regions and varying with seasons. This work may make contribution to a better understanding and control of the increasingly severe air pollution in China as well as other developing Asian countries.
Show more [+] Less [-]Australian atmospheric lead deposition reconstructed using lead concentrations and isotopic compositions of archival lichen and fungi
2016
Wu, Liqin | Taylor, Mark Patrick | Handley, Heather K. | Wu, Michael
Lead concentrations and their isotopic compositions were measured in lichen genera Cladonia and Usnea and fungi genus Trametes from the Greater Sydney region (New South Wales, Australia) that had been collected and archived over the past 120 years. The median lead concentrations were elevated in lichens and fungi prior to the introduction of leaded petrol (Cladonia 12.5 mg/kg; Usnea 15.6 mg/kg; Trametes 1.85 mg/kg) corresponding to early industrial development. During the period of leaded petrol use in Australian automobiles from 1932 to 2002, total median lead concentrations rose: Cladonia 18.8 mg/kg; Usnea 21.5 mg/kg; Trametes 4.3 mg/kg. Following the cessation of leaded petrol use, median total lead concentrations decreased sharply in the 2000s: Cladonia 4.8 mg/kg; Usnea 1.7 mg/kg. The lichen and fungi isotopic compositions reveal a significant decrease in ²⁰⁶Pb/²⁰⁷Pb ratios from the end of 19th century to the 1970s. The following decades were characterised by lower allowable levels of lead additive in fuel and the introduction of unleaded petrol in 1985. The environmental response to these regulatory changes was that lichen and fungi ²⁰⁶Pb/²⁰⁷Pb ratios increased, particularly from 1995 onwards. Although the lead isotope ratios of lichens continued to increase in the 2000s they do not return to pre-leaded petrol values. This demonstrates that historic leaded petrol emissions, inter alia other sources, remain a persistent source of anthropogenic contamination in the Greater Sydney region.
Show more [+] Less [-]Coupling dynamics and chemistry in the air pollution modelling of street canyons: A review
2016
Zhong, Jian | Cai, Xiao-Ming | Bloss, William James
Air pollutants emitted from vehicles in street canyons may be reactive, undergoing mixing and chemical processing before escaping into the overlying atmosphere. The deterioration of air quality in street canyons occurs due to combined effects of proximate emission sources, dynamical processes (reduced dispersion) and chemical processes (evolution of reactive primary and formation of secondary pollutants). The coupling between dynamics and chemistry plays a major role in determining street canyon air quality, and numerical model approaches to represent this coupling are reviewed in this article. Dynamical processes can be represented by Computational Fluid Dynamics (CFD) techniques. The choice of CFD approach (mainly the Reynolds-Averaged Navier-Stokes (RANS) and Large-Eddy Simulation (LES) models) depends on the computational cost, the accuracy required and hence the application. Simplified parameterisations of the overall integrated effect of dynamics in street canyons provide capability to handle relatively complex chemistry in practical applications. Chemical processes are represented by a chemical mechanism, which describes mathematically the chemical removal and formation of primary and secondary species. Coupling between these aspects needs to accommodate transport, dispersion and chemical reactions for reactive pollutants, especially fast chemical reactions with time scales comparable to or shorter than those of typical turbulent eddies inside the street canyon. Different approaches to dynamical and chemical coupling have varying strengths, costs and levels of accuracy, which must be considered in their use for provision of reference information concerning urban canopy air pollution to stakeholders considering traffic and urban planning policies.
Show more [+] Less [-]More than 500 million Chinese urban residents (14% of the global urban population) are imperiled by fine particulate hazard
2016
He, Chunyang | Han, Lijian | Zhang, Robin Q.
China's urbanization and the subsequent public vulnerability to degenerated environment is important to global public health. Among the environmental problems, fine particulate (PM2.5) pollution has become a serious hazard in rapidly urbanizing China. However, quantitative information remains inadequate. We thus collected PM2.5 concentrations and population census records, to illustrate the spatial patterns and changes in the PM2.5 hazard levels in China, and to quantify public vulnerability to the hazard during 2000–2010, following the air quality standards of World Health Organization. We found that 28% (2.72 million km2) of China's territory, including 78% of cities (154 cities) with a population of >1 million, was exposed to PM2.5 hazard in 2010; a 15% increase (1.47 million km2) from 2000 to 2010. The hazards potentially impacted the health of 72% of the total population (942 million) in 2010, including 70% of the young (206 million) and 76% of the old (71 million). This was a significant increase from the 42% of total the population (279 million) exposed in 2000. Of the total urban residents, 76% (501 million) were affected in 2010. Along with PM2.5 concentration increase, massive number of rural to urban migration also contributed greatly to China's urban public health vulnerability.
Show more [+] Less [-]Comprehensive national database of tree effects on air quality and human health in the United States
2016
Trees remove air pollutants through dry deposition processes depending upon forest structure, meteorology, and air quality that vary across space and time. Employing nationally available forest, weather, air pollution and human population data for 2010, computer simulations were performed for deciduous and evergreen trees with varying leaf area index for rural and urban areas in every county in the conterminous United States. The results populated a national database of annual air pollutant removal, concentration changes, and reductions in adverse health incidences and costs for NO2, O3, PM2.5 and SO2. The developed database enabled a first order approximation of air quality and associated human health benefits provided by trees with any forest configurations anywhere in the conterminous United States over time.Comprehensive national database of tree effects on air quality and human health in the United States was developed.
Show more [+] Less [-]Fine particulate matter (PM2.5) in Edmonton, Canada: Source apportionment and potential risk for human health
2016
Bari, Md Aynul | Kindzierski, Warren B.
To design effective PM2.5 control strategies in urban centers, there is a need to better understand local and remote sources influencing PM2.5 levels and associated risk to public health. An investigation of PM2.5 levels, sources and potential human health risk associated with trace elements in the PM2.5 was undertaken in Edmonton over a 6-year period (September 2009–August 2015). The geometric mean PM2.5 concentration of was 7.11 μg/m3 (interquartile range, IQR = 4.83–10.08 μg/m3). Positive matrix factorization (PMF) receptor modeling identified secondary organic aerosol (SOA) as the major contributor (2.2 μg/m3, 27%), followed by secondary nitrate (1.3 μg/m3, 17%) and secondary sulfate (1.2 μg/m3, 15%). Other local sources included transportation (1.1 μg/m3, 14%) and industry-related emissions (0.26 μg/m3, 3.4%), biomass burning (1.0 μg/m3, 13%) and soil (0.54 μg/m3, 6.8%). Five factors (i.e., SOA, secondary nitrate, secondary sulfate, transportation and biomass burning) contributed more than 85% to PM2.5 for the 2009–2015 period. Geometric (arithmetic) mean and maximum ambient air concentrations for hazardous trace elements of public health concern in PM2.5 during the study period were below United States regulatory agency chronic and acute health risk screening criteria. Carcinogenic and non-carcinogenic risk of trace elements and source-specific risk values were well below acceptable and safe levels of risks recommended by regulatory agencies. More work is needed to understand the origin of potential SOA and wintertime wood burning sources in Edmonton and the surrounding region and to apply source-risk apportionment using all available hazardous air pollutants (HAPs) including organic compounds to better interpret the potential health risk posed by various sources in urban areas.
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