The widespread occurrence and ubiquitous distribution of estrogens, i.e., estrone (E1), estradiol (E2), and estriol (E3) in our water matrices, is an issue of global concern. Public and regulatory authorities are concerned and placing joint efforts to eliminate estrogens and related environmentally hazardous compounds, due to their toxic influences on the environmental matrices, ecology, and human health, even at low concentrations. However, most of the available literature is focused on the occurrence of estrogens in different water environments with limited treatment options. Thus, a detailed review to fully cover the several treatment processes is needed. This review comprehensively and comparatively discusses many physical, chemical, and biological-based treatments to eliminate natural estrogens, i.e., estrone (E1), estradiol (E2), and estriol (E3) and related synthetic estrogens, e.g., 17α-ethinylestradiol (EE2) and other related hazardous compounds. The covered techniques include adsorption, nanofiltration, ultrafiltration, ultrasonication, photocatalysis of estrogenic compounds, Fenton, Fenton-like and photo-Fenton degradation of estrogenic compounds, electro-Fenton degradation of estrogenic compounds, ozonation, and biological methods for the removal of estrogenic compounds are thoroughly discussed with suitable examples. The studies revealed that treatment plants based on chemical and biological approaches are cost-friendly for removing estrogenic pollutants. Further, there is a need to properly monitor and disposal of the usage of estrogenic drugs in humans and animals. Additional studies are required to explore a robust and more advanced oxidation treatment strategy that can contribute effectively to industrial-scale applications. This review may assist future investigations, monitoring, and removing estrogenic compounds from various environmental matrices. In concluding remarks, a way forward and future perspectives focusing on bridging knowledge gaps in estrogenic compounds removal are also proposed.

This study developed a process of genetically engineered bacteria Rhodococcus erythropolis expressing Nirs and AMO combined with membrane bioreactor (MBR), nanofiltration (NF) and reverse osmosis (RO) membrane (pRho-NA-MNR) for advanced treatment of landfill leachate. Results demonstrated that pRho-NA-MNR presented higher removal rate of chemical oxygen demand (COD), biological oxygen demand (BOD), ammonia nitrogen (N–NH₄), total nitrogen (TN) and total organic carbon (TOC) than activated sludge (AS-MNR) system. Administration of pRho-NA increased nitrification by converting N–NH₄ to nitrite (N–NO₂) and Nitrate (N–NO₃), and promoting denitrification by converting N–NO₂ to nitrogen (N₂) in the landfill leachate treatment, promoted the pH control, increased sludge activity and effluent yield, shortened phase length adaptation under alternating aerobic-anoxic conditions. pRho-NA increased the nitration and denitrifying rate in the aerobic and anaerobic stage in the system by increasing Cyt cd1 and Cyt c expression in the activated sludge. Nitrogen removal by nitrification and denitrification was positively correlated to the concentration of Nirs and AMO expression. Treatment with pRho-NA promoted pollutant removal efficiency of membrane bioreactor, nanofiltration and reverse osmosis membrane processes in landfill leachate. In conclusion, data suggest that pRho-NA-MNR facilitates the formation of granular sludge and enhances comparable removal of nitrogen and organic compounds, indicating the practice of this process should be considered in landfill leachate treatment system.

Water is the material basis for living organisms and one of the primary resources to maintain the sustainable development of the earth’s ecological environment. As a water purification method, nanofiltration (NF) separation technology has been widely considered by researchers in recent years. However, most of the studies on NF in the literature focus on membrane modification, and there are only a few reviews available. In this paper, the latest research progress of NF is reviewed, and the processes of NF membrane preparation using phase inversion, layer by layer, and interfacial polymerization are described. Polymer materials used for NF membrane preparation are reviewed and the main types of nanofillers to generate thin film nanocomposite membranes, including metal organic frameworks, boron nitride, Ti₃C₂TX, graphene oxide, SiO₂, and iron oxide are discussed. Membrane fouling is inevitable during NF operation and this paper analyzes the mechanisms of fouling and summarizes key pretreatment and cleaning methods required to remediate the long-term effects of cake layer formation. The steric hindrance effect, Donnan effect, and dielectric exclusion are analyzed, and some common characterization methods are summarized. The practical applications of NF are briefly introduced including groundwater, pharmaceutical wastewater, and textile wastewater treatment. Finally, the shortcomings and prospects of the existing research progress are put forward.

During zinc hydrometallurgy process, the chloride ions in the materials go into the leaching solution, which have abominable effects on equipment, electrowinning, and environment. So, it is necessary to remove chloride ions from zinc sulfate solution. The present review outlines the current research of removal methods of chlorine by holistically highlighting the advantages and mechanisms. The main techniques used to remove chloride ions from zinc sulfate solution are also discussed in detail. Among the methods, the precipitation method using copper slag to remove chlorine is widely used and the chlorine removal rate is up to 98%. In addition, the combination of electrochemistry and nanofiltration technology can form a closed-loop production process with less waste output and near-zero emissions. In addition, the challenges and possible future directions of chlorine removal from zinc sulfate solutions are also delineated.

Membrane technology is an outstanding alternative for treating complex textile wastewaters. However, difficulties in the management of the resultant concentrate are the main disadvantage of these membrane technologies. This study is focused on the development of integrative management for membrane concentrate of textile effluent under the principle of discharge regulations that aim to achieve zero-liquid discharge (ZLD). Thus, biologically treated textile wastewater (BTTW) is fed to nanofiltration (NF) and reverse osmosis (RO) membranes with ultrafiltration (UF) pre-treatment, separately. NF concentrates (NFC) and RO concentrates (ROC) are further treated with electrocoagulation (EC) and electro-Fenton (EF) to remove COD and color. After the EC and EF steps, the electrodialysis (ED) method is used for ion removal. Operational costs of each process are calculated. Through the NF of BTTW > 65% COD and 92% color removals were achieved, whereas with the RO process, > 65% COD and 98% color removals were obtained. For NFC, > 80% COD and 91% color removal efficiencies were achieved with EC + ED processes and 57% COD and almost total color removal was achieved with EF + ED processes. For ROC, 71% COD and 85% color removals were obtained with EC + ED processes and 85% COD and 98% color removal was observed with EF + ED processes. Additionally, efficient treatment and concentrate management options were investigated for textile effluent.

Rare earth elements or REEs are a vital and irreplaceable part of our modern technological and digital industries. Among the REEs that are the most critical to be recovered are Ce, La, and particularly, Nd, and Y, due to high demand and at a potential future supply risk. Innovative techniques must be considered to recover REEs from secondary resources. In this study, REEs are extracted from iron mining sludge from Central Anatolia in Turkey. Two different acid solutions were compared, one with a higher acid content (120 ml HCl and 80 ml HNO₃ per liter) and one with lower acid content (20 ml HNO₃ per liter). Nanofiltration, as a process to concentrate the acidic leachate and increase the REE concentration, was carried out at pH levels of 1.5, 2.5, and 3.5 and under 12, 18, and 24 bar operating pressures. SLM studies had been carried out using a PVDF membrane with a pore diameter of 0.45 μm, with three different carriers to separate the REEs from other major elements in the concentrated leachate. Through this analysis, the optimum operating conditions for nanofiltration are at pH 3.5 at 12 bar, using the leach with low acidity, achieving about 90% recovery efficiency of the REEs. SLM studies using 0.3M D2EHPA, with a 3-h reaction time, showed the highest mass flux values for the REEs. Nanofiltration and SLM represent novel methods of REE concentration and extraction from iron mining sludge.

Reverse osmosis (RO) technique plays an important role in the treatment of secondary biochemical effluent. However, the reverse osmosis concentrate (ROC) with high salinity and organic pollutants generated from this process remains a challenge to be tackled. The O₃-assisted UV-Fenton advanced oxidation process (AOP) as a pretreatment for the nanofiltration (NF) was used to treat the ROC of industrial wastewater. The optimal removal rates of COD and UV₂₅₄ were 80.4 and 77.4%, respectively. In the NF process, four types of commercial NF membranes (NF90 (Dow, USA), DK (GE, USA), NT101, and NT103 (NADIR, Germany)) were used to treat the AOP effluent. The effects of operating pressure and feed temperature on ion rejection were investigated. The results show that NF90 and NT103 membranes had better rejections to monovalent ions, while DK and NT101 membranes could effectively separate monovalent and divalent ions and their ion rejections decreased with the increase of feed temperature. With the NF90 membrane, the highest TDS removal rate of 89.65% was obtained at the operating pressure of 1.2 MPa.

Nanofiltration polyamide membranes naturally tend towards biofouling, due to their surface physicochemistries. Nisin, a type of short cationic amphiphilic peptide with antimicrobial properties, has been recognized as a safe antimicrobial for food biopreservation and biomedical applications. This study investigates the impact of nisin on the initial bacterial attachment to membranes, its anti-biofouling properties, and characterizes a non-monotonic correlation between nisin concentration and biofilm inhibition. Nisin was found to inhibit B. subtilis (G+) and P. aeruginosa (G−) attachment to both the nanofiltration membrane and the PES membrane. To determine the mechanism of action, we investigated the polysaccharides, protein, and eDNA as target components. We found that the quantities of polysaccharides and eDNA were significantly changed, resulting in bacterial death and anti-adhesion to membrane. However, there were no discernable impacts on protein. We postulated that nisin could prevent irreversible biofouling by decreasing adhesion, killing bacteria, and reducing biofilm formation. We examined membrane flux behavior through bench-scale cross-flow experiments at a set concentration of nisin (100 μg mL⁻¹), with membrane behavior being confirmed using CLSM images. Results showed that nisin could enhance anti-biofouling properties through both anti-adhesive and anti-bacterial effects, and therefore could be a novel strategy against biofouling of membranes.

The following work provides a perspective on the degradation of cytostatic pollutants through TiO₂ heterogeneous photocatalysis. Cytostatic drugs are emerging pollutants used for cancer treatment found in hospital and domestic wastewater. Small amounts of cytostatic pollutants may pose severe health problems in human beings, animals, and plants after prolonged contact. This research presents a general review of some water treatment methods, such as aerobic activated sludge, enzymatic degradation, nanofiltration and chlorination, that have been used for the degradation or elimination of cytostatic drugs in wastewater. In recent years, photocatalysis has become important to solve this problem; these advanced oxidation process uses pure and modified TiO₂ to degrade cytostatic contaminants and convert them into non-harmful substances or to eliminate them completely. This work contains a comprehensive review of the heterogeneous photocatalysis process and mechanism, and its application on the removal of cytostatic pollutants. Even if research on the topic is still scarce, this literature review provides interesting highlights on the scope of the research field, and the path such research could follow.

Researchers in recent years have utilized a broad spectrum of treatment technologies in treating bakers’ yeast production wastewater. This paper aims to review the treatment technologies for the wastewater, compare the process technologies, discuss recent innovations, and propose future perspectives in the research area. The review observed that nanofiltration was the most effective membrane process for the treatment of the effluent (at >95% pollutant rejection). Other separation processes like adsorption and distillation had technical challenges of desorption, a poor fit for high pollutant load and cost limitations. Chemical treatment processes have varying levels of success but they are expensive and produce toxic sludge. Sludge production would be a hurdle when product recovery and reuse are targeted. It is difficult to make an outright choice of the best process for treating the effluent because each has its merits and demerits and an appropriate choice can be made when all factors are duly considered. The process intensification of the industrial-scale production of the bakers’ yeast process will be a very direct approach, where the process optimisation, zero effluent discharge, and enhanced recovery of value-added product from the waste streams are important approaches that need to be taken into account.