Congenital heart defects (CHDs) are a major cause of death in infancy and childhood. Major risk factors for most CHDs, particularly those resulting from the combination of environmental exposures with social determinants and behaviors, are still unknown. This study evaluated the main effect of maternal environmental tobacco smoke (ETS), and its interaction with social-demographics and environmental factors on CHDs in China. A population-based, matched case-control study of 9452 live-born infants and stillborn fetuses was conducted using the Guangdong Registry of Congenital Heart Disease data (2004–2014). The CHDs were evaluated by obstetrician, pediatrician, or cardiologist, and confirmed by cardia tomography/catheterization. Controls were randomly chosen from singleton newborns without any malformation, born in the same hospital as the cases and 1:1 matched by infant sex, time of conception, and parental residence (same city and town to ensure sufficient geographical distribution for analyses). Face-to-face interviews were conducted to collect information on demographics, behavior patterns, maternal disease/medication, and environmental exposures. Conditional logistic regression was used to estimate odds ratios and 95% confidence intervals of ETS exposure on CHDs while controlling for all risk factors. Interactive effects were evaluated using a multivariate delta method for maternal demographics, behavior, and environmental exposures on the ETS-CHD relationship. Mothers exposed to ETS during the first trimester of pregnancy were more likely to have infants with CHD than mothers who did not (aOR = 1.44, 95% CI 1.25–1.66). We also observed a significant dose-response relationship when mothers were exposed to ETS and an increasing number of risk factors and CHDs. There were greater than additive interactions for maternal ETS and migrant status, low household income and paternal alcohol consumption on CHDs. Maternal low education also modified the ETS-CHD association on the multiplicative scale. These findings may help to identify high-risk populations for CHD, providing an opportunity for targeted preventive interventions.

Perennial contaminated groundwater seepage is threatening the downstream ecosystem of the Kazipally Pharmaceutical industrial area located in South India. The sources of seepage are unknown for the last three decades that challenging the regulatory authorities and industries. In general, water quality monitoring and geophysical techniques are applied to identify the sources. However, these techniques may lead to ambiguous results and fail to identify the seepage sources, especially when the area is urbanized/paved, and groundwater is already contaminated with other leakage sources that have similar chemical compounds. In the present study, a novel and multidisciplinary approach were adopted that includes satellite-based Land Surface Temperature (LST) observations, field-based Electrical Resistivity Tomography (ERT), continuous Soil Electrical Conductivity (SEC) and Volumetric Soil Moisture (VSM%) measurements along with groundwater levels monitoring to identify the sources and to control the seepage. The integrated results identified that the locations with the Standard Thermal Anomaly (STA) in the range of −0.5 to -1 °C, VSM% >50%, SEC > 1.5 mS/cm, bulk resistivity < 12 Ω m with shallow groundwater levels < 3 m below ground level (bgl) are potentially contaminated perennial seepage sources. Impermeable sheet piles have been installed across the groundwater flow direction to control the seepage up to 1.5 m bgl, where groundwater frequently intercepts land surface. The quantity of dry season groundwater seepage has been declined by 79.2% after these interventions, which in turn minimized the treatment cost of 1,96,283 USD/year and improved the downstream ecosystem.

Ammonium persulfate (AP) causes occupational asthma (OA) and diesel exhaust particles (DEP) exacerbate asthma; however, the role of DEP in asthma due to chemical agents has not been assessed to date. Therefore, the present work aims to study the immunomodulatory effects of DEP in a mouse model of chemical asthma. BALB/c ByJ mice were randomly divided into four experimental groups. On days 1 and 8, mice were dermally sensitized with AP or saline. On days 15, 18 and 21, they received intranasal instillations of AP or saline. Two experimental groups received DEP on every of the three challenges. Airway hyperresponsiveness (AHR), lung mechanics, pulmonary inflammation in bronchoalveolar lavage, leukocyte numbers in total lung tissue, oxidative stress and optical projection tomography (OPT) studies were assessed. The AP-sensitized and challenged group showed asthma-like responses, such as airway hyperresponsiveness, increased levels of eosinophils and NKs and lower numbers of monocytes and CD11b-Ly6C- dendritic cells (DCs). Mice exposed to DEP alone showed increased levels of neutrophils and NKs, reduced numbers of monocytes and alveolar macrophages, and increased levels of CD11b + Ly6C- DCs. The AP sensitized and AP + DEP challenged group also showed asthma-like symptoms such as AHR, as well as increased numbers of eosinophils, neutrophils, CD11b + Ly6C- DCs and decreased levels of total and alveolar macrophages and tolerogenic DCs. Particle deposition was visualised using OPT. In the DEP group the particles were distributed relatively evenly, while in the AP + DEP group they were seen mainly in the large conducting airways. The results show that DEP exposure activates the innate immune response and, together with AP, exacerbates asthma immune hallmarks. This mouse model provides the first evidence of the capacity of DEPs to increase CD11b + Ly6C- (Th2-related) DCs. This study also demonstrates, for the first time, a differential deposition pattern of DEP in lungs depending on asthma status.

From 2006 to 2020, groundwater investigations were conducted in the Korba coastal aquifer in northern Tunisia along two flow paths (transects S1 and S2), perpendicular to the shoreline. Groundwater sampling, hydrodynamic monitoring, and electrical tomography imaging were performed in situ. Geochemical analysis (Ionic ratios, ionic deltas, conventional diagrams, and stable isotopes) and modelling using PHREEQC, and multivariate statistical analysis were applied. The objective was to identify the potential origin of groundwater salinization (i.e., high TDS and NO₃) and to study associated processes. The groundwater flow inversion was corroborated by the piezometric survey in transect S1, where a piezometric depression of 5 m was detected at 4000 m from the seashore. Seawater intrusion and agricultural contamination, mainly through N-fertilizers, both contribute to groundwater mineralization and consequently salinization, according to PCA analysis. The impacted geochemical area of seawater intrusion was estimated to be 4000 and 1500 m, respectively, along transect S1 and transect S2. Inversely, agricultural contamination acts in internal areas beginning at 2000 m and 1500 m from the shoreline for S1 and S2, respectively. Results of different scenarios of inverse geochemical modelling along flow paths indicated that mixing, ion exchange, dissolution of gypsum, and precipitation of dolomite and calcite are the main processes controlling the groundwater composition in the coastal study area.

The mining and processing of metal ores in the UK has left a legacy of environmental degradation, and abandoned metal mines still pose a significant threat to terrestrial and fluvial environments. Flow gauging, water quality and geophysics were combined in an integrated assessment of surface and subsurface hydrological contamination at Esgair Mwyn, an abandoned mine in Ceredigion, Wales. Heavy metals discharged from the site are polluting downstream watercourses, leading to widespread Environmental Quality Standards (EQS) compliance failures. Through salt water dilution gauging and water quality sampling, a daily efflux of 876 g of heavy metals was calculated, with contaminant mobilisation occurring mainly in two primary surface streams draining an exposed tailings heap. Electrical resistivity tomography subsurface imaging found a seepage plane within the tailings lagoon wall, whilst the main tailings heap became increasingly saturated with depth. A large adjacent field also had a high potential to convey pollutants in solution, yet its morphological characteristics have limited transmission, as the area acts as a passive treatment type system. With remediation of already polluted water both difficult and expensive, this approach provides a cost-effective way to identify the origins and pathways of contaminants, informing mitigation strategies focussed on containment. Esgair Mwyn is not an isolated case, as abandoned metal mines release at least 860 t of heavy metals annually into UK water bodies. These techniques could reduce or prevent abandoned metal mine hydrological pollution for decades to come, and enable associated UK water bodies to comply with future water quality standards.

Public concerns have been dramatically increased over potential saltwater intrusion resulting in freshwater resources shortage in coastal aquifers in the past decades. Investigating the distribution and origin of saline water is a key factor to understand coastal groundwater evolution and further assist its management. Here we evaluate the horizontal and vertical spatial variability of the coastal groundwater salinity and its potential key influencing factors based on integrated hydrochemical and geoelectrical approaches in the Pearl River Estuary (PRE), South China. The electrical resistivity tomography and geochemical data show a decrease of salinity from the coast to the inland with a water type varying from Cl–Na to HCO₃–Ca at the regional scale. Points with higher/lower salinity values than those in the surrounding environment occasionally exist in the study region. In the cross section, the zone 2–90 m below the surface has low resistivity values, which correspond to high-salinity values in the subsurface. The moderate resistivity values at 0–2 m depth illustrate an infiltration of freshwater. The complex salinity distribution pattern is mainly controlled by the heterogeneity of formation and distribution of primary flow paths, while the coastal groundwater salinity evolution is shaped by the joint influence of paleo-seawater intrusion, the ion mixing processes, and the water–rock interaction.

The article presents the results of the study of the vapor streams from sulfide-containing tailings after gold mining by cyanidation (Ursk waste heaps, Kemerovo region, Russia). The gas survey of sulfur dioxide, dimethyl sulfide, dimethyl sulfoxide, carbon disulfide, and N-containing substances concentrations was carried out using a portable device GANK-4 on a series of profiles covering the waste heaps and the surrounding area with simultaneous measurement of temperatures in the air and soil. The concentration maps-schemes of the studied gases in the surface layer were constructed. The high positive correlation of gases between themselves is established, which indicates similar mechanisms of their formation. The electrical resistivity tomography determined the internal structure of the waste heap. Active “breathing” zones were identified in which the maximum fluctuations in the concentrations of sulfur, selenium, and nitrogen-containing compounds in the near-surface air layer were recorded. Such zones are marked with lower resistances in comparison with other areas on the geo-electric profiles. There is an inverse correlation between the resistivity of the tailings and its temperature and a direct correlation between the concentration of gas in the air and the temperature of the soil. High concentrations of CS₂, the volatile gas compound of the second hazard class, were found in the concentrations that exceed 6–8 times the daily average norm. Further investigation of the mine tailings seasonal transformation with the production of toxic gases deserves special attention due to high environmental risks and poor knowledge of this problem. The oxidation of ore cyanidation wastes in summer and methylation in winter due to seasonal temperature fluctuation lead to production of gases of great concern including toxic СS₂.

Electrical resistivity tomography (2D ERT) is a powerful tool for the diagnosis of the subsoil state and to pursue an environmental monitoring in time to detect and follow a temporal evolution of plumes in hydrocarbon-contaminated soils. In situ, 2D ERT was conducted to investigate the electrical properties of the subsoil in three petrol stations in Murcia semiarid Region (SE Spain), which have been active for many years, in order to look for anomalous areas that could be related to the presence of a non-aqueous phase liquid (NAPL) contaminant plume in the subsoil. A total of 18 ERT profiles in wet and dry season were conducted to study the seasonal effects in the resistivity values of the subsoil. Dipole–dipole array was set up to make the soil diagnosis, achieving a good vertical and lateral resistivity distributions for the sites investigated. Interpretations obtained from ERT pseudo-sections, after a processing and inversion data process with PROSYS II and RES2DINV software, show delimited highly resistive regions above 2,000 Ω·m at 2 m deep related to the underground storage tanks (USTs) position and the filling ports and anomalous resistivity areas where boreholes and further GC–FID determination in soil samples have been done. No significant differences have been found between results obtained in dry and wet seasons. Thus, the geo-electrical non-destructive technique ERT is presented as a tool to delineate the USTs positions and to point out anomaly in the subsoil that could contain NAPL, helping to design sampling strategies, saving cost and time.

The assessment of metals dispersal in polluted mining areas is a very complex issue, usually needing data from several analytical techniques in a joint approach. The present work focuses on the impact of the mining activity on lowlands alluvial plain sediments from an ephemeral creek, their role as source or sink of pollution and the spatial distribution of metals within the zone. In-depth distribution of elements (As, Cd, Co, Cr, Cu, Fe, Mn, Ni, Pb, S, Ti and Zn) coming from mining activities was investigated by using X-ray fluorescence techniques and their mineralogical form using X-ray diffraction. A 2-D electrical resistance tomography field survey was carried out throughout at the creek bed to interpret the potential relationships between chemical, mineralogical and geophysical parameters. The application of leaching procedure (DIN 38414-S4 test) allows us to know the sediment’s heavy metals hazard and their potential mobility when changing redox conditions. From the results it was found that redox process of sulphur and the presence of carbonate influence the distribution of metals along the profile. In the present work, the precipitation of carbonates seems the most important process, especially for elements such as Zn and Mn. Secondary precipitation of sulphides enables the trapping of metals at sulphur-rich levels.

Coastal lands around Bay of Bengal in Central Godavari Delta are mainly agriculture fields and two times annually paddy crops putting in the study area. Canals of Godavari River are the main source of water for irrigation. Geophysical and geochemical investigations were carried out in the study area to decipher subsurface geologic formation and assessing seawater intrusion. Electrical resistivity tomographic surveys carried out in the watershed-indicated low resistivity formation in the upstream area due to the presence of thick marine clays up to thickness of 20–25 m from the surface. Secondly, the lowering of resistivity may be due to the encroachment of seawater in to freshwater zones and infiltration during tidal fluctuation through mainly the Pikaleru drain, and to some extent rarely through Kannvaram and Vasalatippa drains in the downstream area. Groundwater quality analyses were made for major ions revealed brackish nature of groundwater water at shallow depth. The in situ salinity of groundwater is around 5,000 mg/l and there is no groundwater withdrawal for irrigation or drinking purpose in this area except Cairn energy pumping wells which is using for inject brackish water into the oil wells for easy exploration of oil. Chemical analyses of groundwater samples have indicated the range of salt concentrations and correlation of geophysical and borehole litholog data in the study area predicting seawater-contaminated zones and influence of in situ salinity in the upstream of study area. The article suggested further studies and research work that can lead to sustainable exploitation/use and management of groundwater resources in coastal areas.