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Induction of bacterial antibiotic resistance by mutagenic halogenated nitrogenous disinfection byproducts Full text
2015
Lv, Lu | Yu, Xin | Xu, Qian | Ye, Chengsong
Halogenated nitrogenous disinfection byproducts (N-DBPs) raise concerns regarding their mutagenicity and carcinogenicity threatening public health. However, environmental consequence of their mutagenicity has received less attention. In this study, the effect of halogenated N-DBPs on bacterial antibiotic resistance (BAR) was investigated. After exposure to bromoacetamide (BAcAm), trichloroacetonitrile (TCAN) or tribromonitromethane (TBNM), the resistance of Pseudomonas aeruginosa PAO1 to both individual and multiple antibiotics (ciprofloxacin, gentamicin, polymyxin B, rifampin, tetracycline, ciprofloxacin + gentamicin and ciprofloxacin + tetracycline) was increased, which was predominantly ascribed to the overexpression of efflux pumps. The mechanism of this effect was demonstrated to be mutagenesis through sequencing and analyzing antibiotic resistance genes. The same induction phenomena also appeared in Escherichia coli, suggesting this effect may be universal to waterborne pathogens. Therefore, more attention should be given to halogenated N-DBPs, as they could increase not only genotoxicological risks but also epidemiological risks of drinking water.
Show more [+] Less [-]Effects of oil pipeline explosion on ambient particulate matter and their associated polycyclic aromatic hydrocarbons Full text
2015
Zhao, Yue | Cao, Lixin | Zhou, Qing | Que, Qiming | Hong, Bo
Effects of the oil pipeline explosion on PM2.5-associated polycyclic aromatic hydrocarbons (PAHs) and their substituted (alkylated, nitrated, oxygenated, hydroxyl and chlorinated) derivatives are assessed near the accident scene of Qingdao, China. Compared with those in TSP-PM2.5, gaseous phase, burn residue and unburned crude oil, eighty-nine PAHs in PM2.5 are identified and quantified to investigate the composition, temporal and spatial distribution, and sources. The concentrations of PM2.5-associated parent PAHs increase approximately seven times from the non-explosion samples to the explosion samples (mean ± standard deviation: 112 ± 2 vs 764 ± 15 ng/m3), while some substituted products (nitro- and oxy-) increase by two orders of magnitude (3117 ± 156 pg/m3 vs 740 ± 37 ng/m3). The toxicity evaluation indicates the BaP equivalent concentrations (based on the US EPA's toxicity factors) in PM2.5 are much higher than those in the other phases, especially for a long duration after the tragic accident.
Show more [+] Less [-]Pharmaceuticals and personal care products alter the holobiome and development of a medically important mosquito Full text
2015
Pennington, Marcus J. | Rivas, Nicholas G. | Prager, Sean M. | Walton, William E. | Trumble, John T.
The increasing demand for fresh water has forced many countries to use reclaimed wastewater for agricultural purposes. This water contains pharmaceuticals and personal care products (PPCPs) that remain biologically active following passage through wastewater treatment plants. Run-off from farms and contaminated water from treatment facilities exposes aquatic ecosystems to PPCPs. This study examined the effects of PPCPs on a lower trophic organism. Culex quinquefasciatus larvae were reared in water contaminated with environmentally relevant concentrations of common PPCPs. Acetaminophen alone and a mixture of contaminants were found to increase developmental time of larvae. Susceptibility to Bti increased in larvae exposed to antibiotics, acetaminophen, or a mixture of PPCPs. Antibiotics, hormones, and the mixture altered the mosquito bacterial microbiome. Overall, the results indicate that at environmentally relevant concentrations, PPCPs in reclaimed water can have biologically important effects on an ecologically and medically important lower trophic level insect.
Show more [+] Less [-]Colocalization of low-methylesterified pectins and Pb deposits in the apoplast of aspen roots exposed to lead Full text
2015
Rabęda, Irena | Bilski, Henryk | Mellerowicz, Ewa J. | Napieralska, Anna | Suski, Szymon | Woźny, Adam | Krzesłowska, Magdalena
Low-methylesterified homogalacturonans have been suggested to play a role in the binding and immobilization of Pb in CW. Using root apices of hybrid aspen, a plant with a high phytoremediation potential, as a model, we demonstrated that the in situ distribution pattern of low-methylesterified homogalacturonan, pectin epitope (JIM5-P), reflects the pattern of Pb occurrence. The region which indicated high JIM5-P level corresponded with “Pb accumulation zone”. Moreover, JIM5-P was especially abundant in cell junctions, CWs lining the intercellular spaces and the corners of intercellular spaces indicating the highest accumulation of Pb. Furthermore, JIM5-P and Pb commonly co-localized.The observations indicate that low-methylesterified homogalacturonan is the CW polymer that determines the capacity of CW for Pb sequestration. Our results suggest a promising directions for CW modification for enhancing the efficiency of plant roots in Pb accumulation, an important aspect in the phytoremediation of soils contaminated with trace metals.
Show more [+] Less [-]Tracing mercury pathways in Augusta Bay (southern Italy) by total concentration and isotope determination Full text
2015
Bonsignore, M. | Tamburrino, S. | Oliveri, E. | Marchetti, A. | Durante, C. | Berni, A. | Quinci, E. | Sprovieri, M.
The mercury (Hg) pollution of sediments is the main carrier of Hg for the biota and, subsequently, for the local fish consumers in Augusta Bay area (SE Sicily, Italy), a coastal marine system affected by relevant sewage from an important chlor-alkali factory. This relationship was revealed by the determination of Mass Dependent (MDF) and Mass Independent Fractionation (MIF) of Hg isotopes in sediment, fish and human hair samples. Sediments showed MDF but no MIF, while fish showed MIF, possibly due to photochemical reduction in the water column and depending on the feeding habitat of the species. Benthic and demersal fish exhibited MDF similar to that of sediments in which anthropogenic Hg was deposited, while pelagic organisms evidenced higher MDF and MIF due to photoreduction. Human hair showed high values of δ202Hg (offset of +2.2‰ with respect to the consumed fish) and Δ199Hg, both associated to fish consumption.
Show more [+] Less [-]Evaluating potential non-point source loading of PAHs from contaminated soils: A fugacity-based modeling approach Full text
2015
Luo, Xiaolin | Zheng, Yi | Lin, Zhongrong | Wu, Bin | Han, Feng | Tian, Yong | Zhang, Wei | Wang, Xuejun
Soils contaminated by Polycyclic Aromatic Hydrocarbons (PAHs) are subject to significant non-point source (NPS) pollution during rainfall events. Recent studies revealed that the classic enrichment ratio (ER) approach may not be applicable to PAHs. This study developed a model to estimate the ER of PAHs which innovatively applies the fugacity concept. The ER model has been validated with experimental data, which suggested that the transport of PAHs not only depends on their physicochemical properties, but on the sediment composition and how the composition evolves during the event. The modeling uncertainty was systematically examined, and found to be highly compound-dependent. Based on the ER model, a strategy was proposed to practically evaluate the potential NPS loading of PAHs in watersheds with heterogeneous soils. The study results have important implications to modeling and managing the NPS pollution of PAHs (or other chemicals alike) at a watershed scale.
Show more [+] Less [-]Laccase mediated transformation of 17β-estradiol in soil Full text
2015
Singh, Rashmi | Cabrera, Miguel L. | Radcliffe, David E. | Zhang, Hao | Huang, Qingguo
It is known that 17β-estradiol (E2) can be transformed by reactions mediated by some oxidoreductases such as laccase in water. Whether or how such reactions can happen in soil is however unknown although they may significantly impact the environmental fate of E2 that is introduced to soil by land application of animal wastes. We herein studied the reaction of E2 in a model soil mediated by laccase, and found that the reaction behaviors differ significantly from those in water partly because of the dramatic difference in laccase stability. We also examined E2 transformation in soil using 14C-labeling in combination with soil organic matter extraction and size exclusion chromatography, which indicated that applied 14C radioactivity was preferably bound to humic acids. The study provides useful information for understanding the environmental fate of E2 and for developing a novel soil remediation strategy via enzyme-enhanced humification reactions.
Show more [+] Less [-]Mass balance-based regression modeling of PAHs accumulation in urban soils, role of urban development Full text
2015
Peng, Chi | Wang, Meie | Chen, Weiping | Chang, Andrew C.
We investigated the polycyclic aromatic hydrocarbons (PAHs) contents in 68 soils samples collected at housing developments that represent different length of development periods across Beijing. Based on the data, we derived a mass balanced mathematical model to simulate the dynamics of PAH accumulations in urban soils as affected by the urban developments. The key parameters were estimated by fitting the modified mass balance model to the data of PAH concentrations vs. building age of the sampling green area. The total PAH concentrations would increase from the baseline of 267 ng g−1 to 3631 ng g−1 during the period of 1978–2048. It showed that the dynamic changes in the rates of accumulations of light and heavy PAH species were related to the shifting of sources of fuels, combustion efficiencies, and amounts of energy consumed during the course of development.
Show more [+] Less [-]Particulate matter modifies the magnitude and time course of the non-linear temperature-mortality association Full text
2015
Li, Li | Yang, Jun | Guo, Cui | Chen, Ping-Yan | Ou, Chun-Quan | Guo, Yuming
It remains uncertain whether air pollution modifies the magnitude and time course of the temperature-mortality association. We applied a distributed lag non-linear model (DLNM) combined with non-linear interaction terms to assess the modifying effects of particulate matter with an aerodynamic diameter of 10 μm or less (PM10) on the association between mean temperature and mortality in Guangzhou, China. We found that both cold and hot effects increased with the quartiles of PM10. The elderly were more vulnerable to cold and hot effects. Men suffered more from cold-related mortality than women, with the gender difference enlarging with the quartiles of PM10. We identified statistically significant interaction effects between PM10 and mean temperature on mortality (except for respiratory mortality). Cold and hot effects basically appeared acutely on highly polluted days, while effects were delayed on lowly polluted days. The findings indicate the importance of reducing PM10 emission on extremely temperature days.
Show more [+] Less [-]Distribution of mercury in archived fur from little brown bats across Atlantic Canada Full text
2015
Little, Megan E. | Burgess, Neil M. | Broders, Hugh G. | Campbell, Linda M.
Total mercury (Hg) concentrations were measured in archived fur from adult female little brown bats sampled at maternity roosts across Atlantic Canada. Mercury concentrations varied significantly among regions and roosts. Bats from Nova Scotia and Newfoundland had the highest median Hg concentrations (9.67 μg/g and 9.51 μg/g) among regions, and individuals from Kejimkujik National Park had the highest Hg (median: 28.38 μg/g) among roosts. Over one third of individuals sampled had fur Hg concentrations exceeding thresholds associated with neurochemical responses. Within-roost examinations of stable carbon and nitrogen isotopes in fur showed inconsistent associations with Hg concentrations. Therefore, the hypothesis that within-roost variation in Hg is driven by variation in diet is not supported by this data, and it is recommended that key prey items be included in future mercury bioaccumulation studies for bats. The elevated mercury fur concentrations for bats from southern Nova Scotia remains an anomaly of concern even when placed in the larger context of Atlantic Canada.
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