A prospective study was performed on 15 client-owned dogs to assess the clinical outcome after surgical excision of canine cutaneous mast cell tumors (MCTs) depending on histologic grade and completeness of surgical margins. The surgical margins were evaluated as complete, close or incomplete if they were more than 3 mm, from 1 to 3 mm or less than 1 mm wide, respectively. Survival time for dogs with low grade MCT (based on grading by M. Kiupel et al.) was 409 days compared with only 60 days for dogs with high grade tumor. Dogs with high grade tumors had significantly shorter survival time and worse prognosis than dogs with low grade tumors (p=0.013). Complete excision was associated with lower possibility and longer time to tumor recurrence, as well as longer survival, however, marginal surgical border status did not have a significant impact on time to tumor recurrence and survival. It was also found that tumor duration but not tumor size had a significant impact on surgical margin status (p=0.047). Tumor size significantly affected survival time with larger tumors being correlated with shorter survival (p=0.03). The results of our study suggest that grade, tumor size and recurrence are significant factors for MCT prognostication.

The aim of our study was to describe the histopathological and cytological characteristic of the cow endometrium on the seventh day of the oestrous cycle. In this study, 11 different breeds’ dairy cows (78.18 ± 37.46 months old, in 3.6 ± 2.17 lactation, the mean body condition score 3.4 ± 0.72 (5 points scale)) from Research and Study farm ‘Vecauce’ were selected. All cows were more than 210 days postpartum. Overall health and reproductive tract examination was performed, progesterone (P4) and estradiol (E2) concentration in blood serum were established and the biopsy and cytology samples of endometrium were taken. Mean E2 concentration was 14.92 ± 7.92 pg mLE−1, mean P4 concentration was 13.64 ± 9.44 nmol LE−1. The mean percentage in the cytology slides was established: epithelial cells 89 ± 9%, polimorphonuclear leukocytes (PMN) 6 ± 5%. Cytological subclinical endometritis (SE) was confirmed in 5 cows. Histopathological findings (out of 22 samples): endometrium stromal edema in 14, hemosiderin and hemosiderophages in 8, supranuclear vacuolization in 12, pseudodecidual reaction in 12 samples. No subnuclear vacuolization and mitosis in the glandular epithelium were detected. Histopathological examination did not reveal SE. Morphology between the uterine horns with and without corpus luteum (CL) and between cows with serum P4 level higher than 15 nmol LE−1 and lower than 15 nmol LE−1 were not statistically different (p is greater than 0.05). In conclusion, histopatological examination is more reliable diagnostic method for SE. Future investigation should be performed to establish cut-off values for the diagnosis of SE in cows more than 210 days postpartum.