Oxidative stress is present in buffaloes with diaphragmatic hernia not only because of endogenous antioxidant deficiency but also because of reperfusion injury owing to intraoperative animal posture. This study was planned in 12 buffaloes with diaphragmatic hernia which was corrected surgically either with or without positive pressure ventilation. The extent of oxidative stress was estimated by studying MDA and SOD levels in blood. Both MDA and SOD increased at different stages of operation and did not differ significantly in animals with or without positive pressure ventilation.

This study was conducted to assess the therapeutic efficiency of antioxidant in subclinical mastitis. Therapeutic trials were conducted in twelve buffaloes affected with subclinical mastitis and were randomly divided into two groups. The buffaloes of Group 1 were treated with intramuscular injection of Inj. Mofoi 5 mg/kg body weight, while Group 2 buffaloes were treated with intramuscular administration of Inj. Mofoi 5 mg/kg body weight along with antioxidant powder orally. The therapeutic efficacy was assessed based on bacteriological cure and the pre and post therapeutic values of somatic cell count, electrical resistance, pH and milk yield. The use of antioxidant along with Moxifloxacin was found to be superior than antibiotic alone by improving udder's natural defence mechanism, early restoration of milk yield and quick recovery.