Cape Verde, which has agricultural land that is mainly rainfed, will be severely affected by climate change due to increased drought conditions. Scarce water availability makes this country highly dependent on imports for its food supply, resulting in more than 80% food importation. Improving water use efficiency, implementing precision irrigation could help achieve sustainable use of water resources. Cereal production reusing treated water could contribute to strengthening resilience and adaptation to climate change in Cape Verde. Our pilot project demonstrates that the safe and profitable reuse of water produced by Cape Verde’s water treatment plants is possible by avoiding water and plant contact using Subsurface Drip Irrigation (SDI), obtaining food yields between 10,000 and 7000 kg of cob/ha, with a water consumption of about 300 L/kg Dry-Matter and a Water-Use-Efficiency of about 3 g/L. These studies also showed that it is necessary to provide training to farmers and to conduct further studies to help solve present challenges. This project identif installation failures as water shortages can compromise farmers’ profitability. To guarantee the sustainability of water reuse, it is also necessary to consider economic and social factors, including that all water that is not reused is poured, increasing environmental and sanitary risk and decreasing the possibility of recovering water treatment costs.