The purpose of the article is to consider the features of the anthropogenic impact on agricultural land in the Republic of Kazakhstan (RK). The article deals with the current problem of agricultural land degradation, and desertification in Kazakhstan, where one of the causes is the anthropogenic activities of the population and the aridity of the country's climate. Most of the territory of Kazakhstan is located in conditions highly vulnerable to anthropogenic desertification when in combination with natural factors of desertification the ecological situation is sharply deteriorating. Another cause of land degradation is urbanization and intensive degradation of desert habitats — unsystematic road network, regulation of river flows, illegal cutting of saxaul for firewood for sale. As a result of urbanization and intensive agricultural development of the foothill strip in the south and east of the country, the natural vegetation cover is highly disturbed. Roads, pipelines, and power lines, which are being laid at an increasing rate, have a great impact on the fauna. The area of land occupied by mining enterprises is steadily growing. In the last 10 years, the areas of oil and gas extraction, development of uranium ores, etc. in Western Kazakhstan, the Eastern Caspian Sea region, the Betpakdala desert, etc. have been sharply increasing. As a result of insufficiently thought-out land management from water erosion 5.6 million hectares of arable land was affected and grain yield was reduced by 20–30%. Degradation of agricultural lands, including pastures, is 30–50% and higher % in 9 of 14 regions of Kazakhstan. The use of the existing model of agricultural development of raw materials leads to inefficient economic development and constantly increasing pressure on ecosystems. The soil in Kazakhstan is very vulnerable, as it is comprehensively affected by various anthropogenic factors that lead to the constant deterioration of its quality. Soils near the Aral Sea and the Caspian Sea are subjected to the most intensive degradation, as wind erosion is widespread there.