Chemically induced delayed cutaneous hypersensitivity in guinea pigs and rabbits experimentally infected with Mycobacterium bovis
1986
Lee, C.Y. | Lee, C.G. | Park, Y.J. (Chonnam National Univ., Kwangju (Korea R.). Dept. of Veterinary Medicine)
In order to evaluate the effects of the cell-mediated immunity of the animal in the chronic diseases the guinea pigs and rabbits were inoculated with Mycobacterium bovis. After 6 weeks these animals were sensitized and challenged with 2, 4-dinitrochlorobenzene. The cutaneous reactions observed in these animal species were similar each other. Macroscopic and microscopic responses in the animal experimentally infected with M. bovis were markedly reduced compared to those in the control animals
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