Organochlorine contaminants (OCC) in human colostrum
1997
Vukavic, T. (Medicinski fakultet, Novi Sad (Yugoslavia). Institut za zdravstvenu zastitu dece i omladine) | Vojinovic-Miloradov, M. | Pavkov, S. | Nikolic, D.
The aim of the study was to quantify the levels of organochlorine contaminants (OCC) residues in human colostrum in 1993 and compare them with previous results obtained in the same geographical region in Yugoslavia and in the same season of 1982. Fifteen samples of colostrum were collected in November-December 1993, from healthy mothers chosen at random, who gave birth to healthy, mature neonates after uncomplicated pregnancy and delivery. Colostrum, in the amount of 20-30 ml was manually expressed on 3rd day after delivery. It was immediately frozen at -20 deg C, until analysed. Concentrations of total DDT were significantly lower (p=6.3E-4) in 1993 than in 1982. The same was for PCBs (p=6.9E-5). Concentration of total HCH, were only nonsignificantly lower in 1993, due to the increase of beta-HCH. The levels of DDT and PCBs, measured in 1993, were below the lowest levels in human milk quoted in the literature. The levels of total HCH, measured in 1993, are higher then found in the literature, and gama-HCH are within the range of these values. Estimated intake per kg b.w., by a newborn on the 3rd day of life in 1993, was below WHO ADI for total DDT and total HCH and US ADI for PCBs.
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