Investigations on the tolerable limit values and the perinatal toxic effect of mycotoxins produced by Fusarium moniliforme
2000
Zomborszkyne Kovacs, M. | Vetesi, F. | Kovacs, F. | Bata, A. | Repa, I. | Horn, P.
In order to determine tolerable limit values, the effect of fumonisin B1 (FB1) administrated in the fungal culture of Fusarium moniliforme in low doses (10, 20 and 40 ppm) for 4 weeks was examined in weaned pigs. Feeding with toxin exerted no significant effect on body weight gain and feed consumption, no clinical signs were observed. In computer tomographic examinations performed in the second and fourth week mild and severe pulmonary oedema was diagnosed. The mathematical/statistical procedure applied on the basis of the findings of the CT examinations and the density values obtained proved appropriate for the in vivo detection of changes developing in the pulmonary parenchyma.
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