Microsatellite polymorphism in DRB1 gene (MHC class II) and its relation to nematode faecal egg count in Polish Heath Sheep
2002
Charon, M.K. (Warsaw Agricultural University (Poland). Dept. of Genetics and Animal Breeding) | Moskwa, B. (Polish Academy of Sciences, Warsaw (Poland). W. Stefanski Inst. of Parasitology) | Rutkowski, R. | Gruszczynska, J. | Swiderek, W.
DNA analysis of the examined sheep showed the presence of 200 alleles in locus DRB1, established on the basis of the length of a fragment of this gene amplified using PCR. The analysis of variance conducted for the FEC trait in genotyping groups showed a statistically significant association between the genotype in locus DRB1 and number of nematode eggs in sheep faeces. The presence of a given DRB1 allele in the genotype of animals examined had significant effect on parasite resistance. Moreover, the significant association between FEC value in allelic groups of paternal half-sibs and the segregation of paternal alleles was also significant
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