Zetamethrin post-exposure haemato-immuno modulations in non-vaccinated chicks (Gallus domesticus)
2002
Arshad, N. | Murtaza, A. | Mahmood, S. (Punjab Univ., Lahore (Pakistan). Dept. of Zoology) | Iqbal, Z. | Arshad, M.
Study was designed to find Zetamethrin post-exposure haemato-immuno modulations in non-vaccinated broiler chicks. Zetamethrin was administered at the rate of 1.265 plus minus 0.198 mg/kg body weight / day for six weeks. It induced persistent anaemia, but reversible changes in haematological parameters and serum proteins. A significant (P less than 0.05) depletion in haemoglobin level (Hb), total leukocyte count (TLC), mean corpuscular haemoglobin (MCH) and mean corpuscular hemoglobin concentration (MCHC) was recorded after six weeks of intoxication. Whereas, elevated serum protein levels were observed at the same time. Hemoglobin contents and mean cell haemoglobin concentration remained significantly low after six weeks of removal of stress (P less than 0.05). Total serum proteins and total leukocyte contents were found in normal range following 15 days of removal of stress, whereas mean corpuscular haemoglobin was restored to normal level after 15 days of removal of stress.
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