Effect of fermented milk on the activities of fecal bacterial enzymes of mice
2001
Nara, M. (Tokyo Univ. of Agriculture (Japan)) | Furukawa, N. | Matsuoka, A. | Takahashi, T. | Yamanaka, Y.
The fecal enzymes originating from the injurious bacteria in the intestinal tract, azoreductase and nitroreductase, convert pro-carcinogens to proximal carcinogens. The effect of fermented milk on the activity of fecal enzymes in mice was studied. The fermented milk was prepared using 1% low-fat milk with the starter of Lactobacillus gasseri JCM 1130 and Lactobacillus amylovorus JCM 5811. Mice were fed with diets containing high contents of protein and fat. When administered fermented milk as Lactobacillus strains supplement, the mice exhibited significantly lower levels of azoreductase and nitroreductase activities in the feces as compared with the levels of their activities in the feces of nontreated mice. The number of viable lactic acid bacteria increased in the mice feces for 5 days after the administration of fermented milk, and the same species of lactic acid bacteria from fermented milk was detected in their feces by using random amplified polymorphic DNA (RAPD) method.
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