Spontaneous complex odontoma in a Sprague-Dawley rat
2002
Jang, D.D. (Korea Food and Drug Administration, Seoul (Korea R.)) | Kim, C.K. | Ahn, B. | Kang, J.S. | Nam, K.T. | Kim D.J. | Han, D.U. | Jung, K. | Chung, H.K. | Ha, S.K. | Choi, C. | Cho, W.S. | Kim, J. | Chae, C.
Complex odontoma from a female Sprague-Dawley rat is described histopathologically. Necropsy revealed a hard (bony), white mass (3.0 x 3.0 x 2.1 cm) on the left mandible. Microscopically, the mass consisted of islands or nests of epithelial and mesen-chymal elements that formed abortive tooth structures. In other areas, tooth formation consisted of a pulp cavity lined by layers of odontoblasts, dentin, enamel, and ameloblasts. Concerning all features of normal tooth formation which was differentiated and mineralized yet completely disorganized, the diagnosis of complex odontoma was recommended.
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