Genetic Polymorphism of Glutathione S-transferase P1 and Breast Cancer Risk
Kim, S.U.;Lee, K.M.;Yoo, K.Y.;Noh, D.Y.;Choe, K.J.;Kang, D.H.(Seoul National University College of Medicine, Cancer Research Institute, Seoul, Republic of Korea)E-mail:[email protected] | Park, S.K.(Konkuk University College of Medicine, Chungju, Republic of Korea) | Ahn, S.H.(Ulsan University College of Medicine, Seoul, Republic of Korea) | Hirvonen, Ari(Finnish Institute of Occupational Health, Helsinki, Finland)
To evaluate the potential association between the GSTP1 genotype and the development of breast cancer, a hospital based case-control study was conducted on Korean women. The study population consisted of 171 histologically confirmed incident breast cancer cases and 171 age-matched controls with no present or previous history of cancer. PCR-RFLP was used for the GSTP1 genotyping and statistical evaluations were performed using an unconditional logistic regression model.
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