Different Sources of Ñ°3 Fatty Acids at the Fixed Ratio of p/s Affect Glutathione Dependent Enzymes in Rat Hepatocarcinogenesis
2003
Lee, H.J. | Kim, H.K. | Choi, H.M. (Seoul National University, Seoul, Republic of Korea)
This study is conducted to determine the effects of dietary source of Ñ°3 fatty acids on preneoplastic foci and the glutathione dependent enzymes in rat hepatocarcinogenesis initiated by diethylnitrosamine (DEN). Male Sprague Dawley rats were fed one of three diets containing 10(w/w) fats fixed p/s = -1.0 and Ñ°6/Ñ°3 ratio = -0.4 or 4.0 ; fish oil-corn oil blended (FC), corm oil-beef tallow-fish oil blended (CF), corm oil-beef tallow-perilla oil blended(CP), from gestation period.
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