Feasibility Study for a Lab-chip Development for LAL Test
2003
Hwang, S.Y. | Choi, H.J. | Suh, C.W. | Ahn, Y.M. | Kim, Y.S. | Lee, E.K. (Hanyang University, Ansan, Republic of Korea)
LAL (Limulus amebocyte lysate) test to detect and quantity endotoxin is based on gellation reaction between endotoxin and LAL from a blood extract of Limulus Polyphemus. The test is labor intensive requiring dedicated personnel, takes relatively long reaction time (approximately 1 hr), requires relatively large volume of samples and reagents, and its end-point detection method is rather subjective.
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